The 10 Best Heart & Liver Supplements for Cats

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How we created this heart & liver supplement list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best heart & liver supplements for cat.

We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best heart & liver supplements for cats.

Key heart & liver supplement considerations

Dosage

Effectiveness

Form

Ingredients

1

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Rated 4.6 out of 5 stars

1,461

$31.99Chewy Price

($1.07/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.4/5

Great

Effectiveness

4.5/5

Great

Form

4.4/5

Great

Ingredients

4.4/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

Small Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: S-Adenosylmethionine, Silybin A+B

Health Feature

Liver Care

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2

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rated 4.6 out of 5 stars

301

$46.99Chewy Price

($0.27/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.4/5

Great

Effectiveness

4.5/5

Great

Form

4.4/5

Great

Ingredients

4.2/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

Ingredients per capsule: Milk Thistle Extract 100 mg (EMed-MT premium providing 80% Silymarin and 30% silybinin) Inositol 20 mg Choline 20 mg DL-Methionine(pharmaceutical grade) 20 mg Pantothenic Acid (calcium pantothenate) 10 mg Vitamin B-1 (thiamine) 5 mg Vitamin B-2 (riboflavin) 5 mg Vitamin B-6 (pyridoxine) 5 mg Alpha Lipoic Acid 5 mg Vitamin B-12 (cyanocobalamin) 10 mcg Inactive ingredients: Gelatin‚ glycerin‚ silica and water

Food Flavor

Unflavored

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3

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Fera Pets Cardiac Support Salmon Flavor Supplement for Dog & Cat, 120 capsules

Rated 4.6 out of 5 stars

104

$44.95Chewy Price

($0.38/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.4/5

Great

Effectiveness

4.4/5

Great

Form

4.4/5

Great

Ingredients

4.3/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active: L-Carnitine Tartrate 300mg, Taurine 250mg, Coenzyme Q10 50mg, Organic Hawthorn Berry 50mg, Vitamin E (D Alpha Tocopherol) 10IU

Special Diet

Non-GMO, Soy Free, Grain-Free, Gluten Free

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4

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Rated 4.6 out of 5 stars

202

$25.99Chewy Price

($0.35/g)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.3/5

Great

Effectiveness

4.2/5

Great

Form

4.2/5

Great

Ingredients

4.3/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

Ground Milk Thistle (Supports Healthy Liver Function)

Food Flavor

Unflavored

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5

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 60 count

Rated 4.2 out of 5 stars

110

$41.64Chewy Price

($0.70/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

3.7/5

Good

Effectiveness

4.5/5

Great

Form

4.2/5

Great

Ingredients

4.0/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients Per 3 g Soft Chew: Milk Thistle 200 mg, Dandelion Root 75 mg, Vitamin C (Calcium Ascorbate) 50 mg, Thiamine (Vitamin B1) 30 mg, Glutathione 20 mg

Food Flavor

Unflavored

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6

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

VetriScience Cardio Strength Capsules Heart Supplement for Cats & Dogs, 90 count

Rated 4.2 out of 5 stars

261

$30.49Chewy Price

($0.34/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.1/5

Great

Effectiveness

4.4/5

Great

Form

4.1/5

Great

Ingredients

4.0/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: L-Carnitine HCl, L-Taurine, N, N-Dimethylglycine HCl, D-Alpha Tocopheryl Succinate (Vitamin E)

Health Feature

Heart Care

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7

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Rated 4.7 out of 5 stars

157

$23.99Chewy Price

($0.80/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.4/5

Great

Effectiveness

4.3/5

Great

Form

4.4/5

Great

Ingredients

4.4/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

Extra Small Breeds, Small Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

S-Adenosylmethionine

Health Feature

Liver Care

View Item Details

8

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Rated 4.3 out of 5 stars

52

$24.97Chewy Price

($14.69/oz)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.3/5

Great

Effectiveness

4.4/5

Great

Form

4.6/5

Excellent

Ingredients

4.3/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Japanese Knotweed (Polygonum cuspidatum) Root, (Providing 15mg of Resveratrol), Milk Thistle (Seed) Extract, Organic Chlorella (Chlorella vulgaris), Sunflower Lecithin

Special Diet

Non-GMO, Gluten Free, Soy Free

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9

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Rated 4.4 out of 5 stars

35

$37.95Chewy Price

($18.98/fl oz)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.2/5

Great

Effectiveness

4.4/5

Great

Form

4.4/5

Great

Ingredients

4.4/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active: Boldo 4X, Carduus Marianus 4X, Chelidonium Majus 4X, Cynara Scolymus 4X, Kali Muriaticum 12X

Special Diet

Plant Based, Natural

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10

VetriScience Coenzyme Q10 10 mg Capsules Heart Supplement for Cats & Dogs, 100 count

VetriScience Coenzyme Q10 10 mg Capsules Heart Supplement for Cats & Dogs, 100 count

VetriScience Coenzyme Q10 10 mg Capsules Heart Supplement for Cats & Dogs, 100 count

VetriScience Coenzyme Q10 10 mg Capsules Heart Supplement for Cats & Dogs, 100 count

VetriScience Coenzyme Q10 10 mg Capsules Heart Supplement for Cats & Dogs, 100 count

Rated 4.6 out of 5 stars

94

$13.49Chewy Price

($0.14/ea)

Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.5/5

Great

Effectiveness

4.6/5

Excellent

Form

4.3/5

Great

Ingredients

4.3/5

Great

Is this heart & liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Coenzyme Q10., Inactive Ingredients: Cellulose, Gelatin, Maltodextrin, Silicon Dioxide

Food Flavor

Unflavored

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