10 Best Liver Supplements for Cats 2026: According to Reviews | Chewy

The 10 Best Liver Supplements for Cats

How we created this liver supplement list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best liver supplements for cat.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best liver supplements for cats.

Key liver supplement considerations

Dosage

Effectiveness

Form

Ingredients

Our Top Picks

1
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle
Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Nutramax Denamarin with S-Adenosylmethionine & Silybin Tablets Liver Supplement for Small Dogs & Cats, 30 count bottle

Rated 4.6 out of 5 stars
1,920
$33.99 Chewy Price
($1.14/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.3/5
Great

Effectiveness

4.5/5
Great

Form

4.4/5
Great

Ingredients

4.3/5
Great

Is this liver supplement right for my pet?

Breed Size

Small Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: S-Adenosylmethionine, Silybin A+B

Packaging Type

Bottle
View Item Details
2
Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count
Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count
Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count
Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count
Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count
Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rx Vitamins Hepato Support Liver Supplement for Cats & Dogs, 180 count

Rated 4.6 out of 5 stars
379
$46.99 Chewy Price
($0.27/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.4/5
Great

Effectiveness

4.5/5
Great

Form

4.4/5
Great

Ingredients

4.3/5
Great

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

Ingredients per capsule: Milk Thistle Extract 100 mg (EMed-MT premium providing 80% Silymarin and 30% silybinin) Inositol 20 mg Choline 20 mg DL-Methionine(pharmaceutical grade) 20 mg Pantothenic Acid (calcium pantothenate) 10 mg Vitamin B-1 (thiamine) 5 mg Vitamin B-2 (riboflavin) 5 mg Vitamin B-6 (pyridoxine) 5 mg Alpha Lipoic Acid 5 mg Vitamin B-12 (cyanocobalamin) 10 mcg Inactive ingredients: Gelatin‚ glycerin‚ silica and water

Food Flavor

Unflavored
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3
Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar
Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar
Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar
Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar
Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Herbsmith Herbal Blends Milk Thistle Powdered Dog & Cat Supplement, 75g jar

Rated 4.6 out of 5 stars
236
$25.99 Chewy Price
($0.35/g)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.3/5
Great

Effectiveness

4.2/5
Great

Form

4.3/5
Great

Ingredients

4.4/5
Great

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

Ground Milk Thistle (Supports Healthy Liver Function)

Food Flavor

Unflavored
View Item Details
4
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count
VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count

VetClassics Liver Support Soft Chews Dog & Cat Supplement, 120 count

Rated 4.2 out of 5 stars
140
$57.99 Chewy Price
($0.49/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

3.7/5
Good

Effectiveness

4.4/5
Great

Form

4.1/5
Great

Ingredients

3.9/5
Good

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients Per 3 g Soft Chew: Milk Thistle 200 mg, Dandelion Root 75 mg, Vitamin C (Calcium Ascorbate) 50 mg, Thiamine (Vitamin B1) 30 mg, Glutathione 20 mg

Food Flavor

Unflavored
View Item Details
5
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle
Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle

Pet Wellbeing Milk Thistle Bacon Flavored Liquid Liver Supplement for Dogs & Cats, 2-oz bottle

Rated 4.4 out of 5 stars
121
$40.95 Chewy Price
($20.48/oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.6/5
Excellent

Effectiveness

4.5/5
Great

Form

4.3/5
Great

Ingredients

4.5/5
Great

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Organic Milk Thistle Seed (Silybum marianum)., Inactive Ingredients: Deionized Water, Natural Bacon Flavor (Glycerin-Based), Vegetable Glycerin

Food Flavor

Bacon, Liver, Meat
View Item Details
6
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count
Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Nutramax Laboratories Denosyl Liver Health Supplement Stabilized Tablets for Small Dogs & Cats, 30 count

Rated 4.7 out of 5 stars
183
$24.99 Chewy Price
($0.84/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.3/5
Great

Effectiveness

4.2/5
Great

Form

4.3/5
Great

Ingredients

4.3/5
Great

Is this liver supplement right for my pet?

Breed Size

Extra Small Breeds, Small Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

S-Adenosylmethionine

Packaging Type

Box
View Item Details
7
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar
Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar

Fera Pets Liver Support with Milk Thistle & Turmeric Powder for Dogs & Cats, 2.5-oz jar

Rated 4.3 out of 5 stars
66
$29.95 Chewy Price
($11.98/oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.1/5
Great

Effectiveness

4.4/5
Great

Form

4.3/5
Great

Ingredients

4.4/5
Great

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

Adult, All Lifestages

Top Ingredients

Milk Thistle Extract: 150 mg, Turmeric Curcumin C3 Complex®: 75 mg, N-Acetyl-L-Cysteine: 50 mg, Ascorbic Acid: 25 mg, Choline: 25 mg

Food Flavor

Chicken
View Item Details
8
Animal Essentials Milk Thistle Liquid Supplement for Dogs & Cats, 1-fl oz bottle
Animal Essentials Milk Thistle Liquid Supplement for Dogs & Cats, 1-fl oz bottle
Animal Essentials Milk Thistle Liquid Supplement for Dogs & Cats, 1-fl oz bottle

Animal Essentials Milk Thistle Liquid Supplement for Dogs & Cats, 1-fl oz bottle

Rated 4 out of 5 stars
65
$18.36 Chewy Price
($18.36/fl oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

3.8/5
Good

Effectiveness

3.9/5
Good

Form

4.1/5
Great

Ingredients

4.1/5
Great

Is this liver supplement right for my pet?

Top Ingredients

Organic Milk Thistle Seed Extract, Silymarin, Vegetable Glycerin USP, Distilled Water, Grain Alcohol 40% by Volume

Special Diet

Plant Based

Packaging Type

Bottle

Health Feature

Liver Care, Diabetic Support, Immune Support, Recovery
View Item Details
9
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle
Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Prana Pets Liver Function Support Liquid Cat & Dog Supplement, 2-fl oz bottle

Rated 4.4 out of 5 stars
43
$37.95 Chewy Price
($18.98/fl oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.0/5
Great

Effectiveness

4.2/5
Great

Form

4.1/5
Great

Ingredients

4.2/5
Great

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active: Boldo 4X, Carduus Marianus 4X, Chelidonium Majus 4X, Cynara Scolymus 4X, Kali Muriaticum 12X

Special Diet

Plant Based, Natural
View Item Details
10
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar
Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Bark and Whiskers Detox Support Dog & Cat Supplement, 1.7-oz jar

Rated 4.2 out of 5 stars
61
$24.97 Chewy Price
($14.69/oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Dosage

4.6/5
Excellent

Effectiveness

4.2/5
Great

Form

4.2/5
Great

Ingredients

4.6/5
Excellent

Is this liver supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Japanese Knotweed (Polygonum cuspidatum) Root, (Providing 15mg of Resveratrol), Milk Thistle (Seed) Extract, Organic Chlorella (Chlorella vulgaris), Sunflower Lecithin

Special Diet

Non-GMO, Gluten Free, Soy Free
View Item Details
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