Comfort Zone Calming Pheromone Diffuser Refill for Cats, 30-day, 6 count

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At a Glance

  • Calming
  • All Lifestages

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About This Item

Details

  • These refills are compatible with Comfort Zone diffusers (sold separately) and the diffuser is reusable for up to 12 months when you replace the refill monthly.
  • The pheromones help create a calm environment that encourages positive behaviors for your furbaby.
  • This is a drug- and fragrance-free solution so you can feel good about helping your cat feel good.
  • This product meets Intertek electrical safety and certified to UL standards.
  • Comfort Zone has provided care with cat calming pheromones for over 20 years, making it a trusted choice for pet parents.

Ingredient Information

Instructions

Learn More About Comfort Zone From Our Team of Experts

About Comfort Zone Cat Calming Diffuser

Curb Stress in Your Cat

Just like people, cats behave differently when stressed. Comfort Zone products help relax your cat to curb stress-related, disruptive behavior so your cat can feel and behave her best.

24/7 Behavioral Support

Place one Comfort Zone Calming Diffuser in each of your cat’s favorite rooms for a happier, calmer cat.

Promotes Positive Behavior

The trusted, drug-free mist in the Comfort Zone Calming Diffuser helps reduce stress and promote positive behavior in your cat. Use it to help your cat adapt to life changes like a new baby, new pet, house guests, routine shifts and more.

How it Works

The Comfort Zone calming mist dispensed by the diffuser contains pheromones that mimic a cat’s natural feline facial pheromones (FFP). These are the same pheromones your cat would leave behind when head bunting you or rubbing her face on the furniture, and they signal to your cat that a place or object is safe and familiar. Using the diffuser can help make new objects or places feel more comfortable—just like one big kitty face rub spread across the entire room!

How to Use

Always use the diffuser properly and with the vents facing up. Leave four feet of space around the diffuser and avoid plugging it under shelves, behind furniture or near vents and windows for best results. Replace the refill approximately every 30 days or earlier if you notice it is empty.

Vet Recommended

Provides behavioral support for cats 10 months and older when used as directed.

Improved Behavior

The diffuser helps reduce stress and promote positive behaviors, with noticeable improvement in as little as two weeks.

Pheromone Technology

Comfort Zone makes a full line of pheromone products to help your cat feel better.

Promotes Relaxation

The calming mist signals a feeling a safety to your cat, lowering stress levels and promoting relaxation.

About Comfort Zone

Comfort Zone is dedicated to helping cats feel safe, calm and happy using signals they naturally understand. They make a wide range of products designed to promote positive behaviors and lower stress in cats. Their drug-free calming solutions can be used in and around the home or on the go. Take Comfort Zone anywhere your kitty needs to feel relaxed, safe and stress-free!

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Frequently bought together

Questions & Answers

11 Customer Questions

Can this be used at the same time as the multi-cat version?

Is there a difference between the multi cat one and the regular calming one?

Will this work with a Feliway diffuser?

Answer by Chewy • Jul 20, 2021
Comfort Zone refills are not designed for use with other diffusers. We recommend using the refills with only the Comfort Zone diffusers.

Will the refills still fit the older designed diffusers?

Answer by Chewy • Aug 06, 2019
These refills are compatible with the new and previous Comfort Zone Diffuser designs.
Reviews
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4.5
Rated 4.5 out of 5 stars
396 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Coverage Area

84% Positive

Duration

83% Positive

Ease of Use

88% Positive

Effectiveness

84% Positive

191 Customer Reviews

Rated 5 out of 5 stars
By Barbara on Jan 12, 2026

The diffusers really work

My husband has Demineta. We have pets and they are attached to my husband, they now come to him and want to be petted all the time. Our son has a dog, and the dog

My husband has Demineta. We have pets and they are attached to my husband, they now come to him and want to be petted all the time. Our son has a dog, and the dog will sleep with my husband in his recliner all the time. I would recommend the diffusers.

Rated 4 out of 5 stars
By Allison on Jan 27, 2026

Cats anxiety seems to be at least somewhat improved.

She seems to have calmed down and may have stopped or at least decreased her peeing. She hasn’t peed on furniture which is what she was doing.

She seems to have calmed down and may have stopped or at least decreased her peeing. She hasn’t peed on furniture which is what she was doing.

Rated 5 out of 5 stars
By Deming on Nov 23, 2025

Incredible

Was very skeptical, but within a day there was a noticeable change in everyone. I have 3 cats. One was becoming aggressive, one was very stressed, but soon there

Was very skeptical, but within a day there was a noticeable change in everyone. I have 3 cats. One was becoming aggressive, one was very stressed, but soon there was calm. They were getting along.

Rated 5 out of 5 stars
By Linda on Jan 21, 2026

Simon is able to stay calm in the house longer with the pheromone difuser.

He is too good at catching birds so this helps to preserve the wildlife in my area.

He is too good at catching birds so this helps to preserve the wildlife in my area.

Rated 3 out of 5 stars
By Lynn on Jan 3, 2026

Bully!

I'm hoping Nimbus will stop being a bully, but haven't found the best spot to locate the diffuser

I'm hoping Nimbus will stop being a bully, but haven't found the best spot to locate the diffuser

Rated 2 out of 5 stars
By brenda on Jan 7, 2026

I was hoping this would settle disputes

I can’t tell this did a thing. I am still relying on the dog to break up cat disputes

I can’t tell this did a thing. I am still relying on the dog to break up cat disputes

Rated 5 out of 5 stars
By Sandra on Jan 19, 2026

It has helped.

It seems that this has really helped the cat and she is doing better.

It seems that this has really helped the cat and she is doing better.

Rated 3 out of 5 stars
By Angela on Aug 8, 2025

works but kind of messy/dangerous

The phermones work to help calm my skitdish cat but the plug itself gets really hot and the oil gets all over the wall around the outlet and the plug itself. Theres

The phermones work to help calm my skitdish cat but the plug itself gets really hot and the oil gets all over the wall around the outlet and the plug itself. Theres no indicator for when it runs out of oil and it'll start overheating if it's dry and still trying to work. I ended up discontinuing use of it after realizing how dangerous it is. I just use the spary bottles, it's more work but it's safer.

Rated 1 out of 5 stars
By Kate on Aug 22, 2025

Hoping too much!!

Our two cats have routines to avoid one another. One is a night owl, the other is a morning robin. There are two turns where they pass each other that are so tense

Our two cats have routines to avoid one another. One is a night owl, the other is a morning robin. There are two turns where they pass each other that are so tense I hold my breath. I tried this product twice and it didn't have any impact. It might work for you, some see results. It didn't work for us.

Rated 5 out of 5 stars
By Heather on Aug 3, 2025

May have worked.

This product is easy to use and recommended by my vet. I've moved apartments twice in the last 2 years and used this product to reduce his stress. He's transitioned

This product is easy to use and recommended by my vet. I've moved apartments twice in the last 2 years and used this product to reduce his stress. He's transitioned with no issues both times. Either the product works very well or my cat just has no issues moving, idk. I will order refills if I move again.