Credelio Chewable Tablet for Dogs, 6.1-12 lbs

Prescription Item

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Count: 1 count
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Credelio is a chewable tablet prescribed to provide monthly protection against ticks and fleas and may also be used for the treatment of flea infestations. Credelio is suitable for dogs and puppies 8 weeks of age and older, weighing at least 6.1 pounds. This medication starts working in just four hours and provides 100% monthly efficacy against fleas and more than 97% monthly efficacy against ticks. Plus, since this medication comes in a chewable tablet form, you can easily disguise it in your dog’s favorite food.


Credelio kills adult fleas and is indicated for the treatment of flea infestations and the treatment and control of tick infestations for one month in dogs and puppies 8 weeks of age and older, and weighing 4.4 pounds or greater.

Possible Side Effects

No serious side effects have been reported.

Drug & Food Interactions

No adverse reactions were observed from the concomitant use of Credelio with other medications. 


The safe use of Credelio in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures.

  1. Prescribing Information

See all items by Credelio

  • Item Number
  • Common Brand Name(s)
  • Dosage Measure
    Credelio is given orally once a month, at the minimum dosage of 9 mg/lb.
  • Generic Name
  • For Use With
    Dogs - 8 weeks or older
  • Brand
  • Breed Size
    Extra Small & Toy Breeds, Small Breeds
  • Product Form
    Chewable Tablet
  • Health Condition
    Fleas, Ticks
  • Drug Type


Recommended Dosage

Credelio is given orally once a month, as directed by your veterinarian.

Storage Instructions

Store at temperatures between 59° - 77°F.


What is lotilaner, the active ingredient in Credelio?

Lotilaner is a member of the isoxazoline class of parasiticides. It has acaracidal and insecticidal activity, and acts as an inhibitor of gamma-aminobutyric acid (GABA)–gated chloride channels (GABACls).

Can Credelio be given to dogs with food allergies?

Credelio tablets are made with a beef flavoring containing pork liver and soy but no actual beef. Tablets also contain barley, wheat and lactose. Consult your veterinarian before using in dogs with food allergies to pork, soy, barley, wheat or lactose.

What is the acceptability/ palatability of Credelio

In a field trial, the acceptability of credelio was tested at 10 different locations across the u.s. 94% of dogs accepted Credelio from the hand, in the bowl or with food. The remaining 6% accepted Credelio when placed in the mouth. There were no reports of unsuccessful dosing.

The positive control in the u.s. field trial was Nexgard® (afoxolaner). Acceptability results were very similar, with only 4% reaching the “placed in mouth” stage. Also, Nexgard had no reports of unsuccessful dosing.

What is the shelf life of Credelio?

Please reference the individual packaging of Credelio for the expiration date.

How long does a Credelio tablet remain stable outside the blister pack?

No stability testing has been performed on tablets once they have been removed from the blister pack. We do not recommend taking the tablets out of the blister pack for storage in another container. Credelio tablets should only be taken out of the blister pack at the time of dosing.

Is Credelio gluten-free?

Yes, Credelio is considered gluten-free.


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  • 5 out of 5 stars

    Excellent customer service for this product!

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    My dog is very sensitive to flea/tick and heartworm medications and I was worried about changing her current flea/tick medication to Credelio. She has had two doses so far and has tolerated both very well. The Chewy folks were very helpful in contacting my vet for the prescription, and I received the product in just two days. YAY CHEWY!!!!!!!!!!

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