Cyproheptadine HCl (Generic) Tablets, 4-mg, 1 tablet

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About This Item

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Cyproheptadine HCI is an antihistamine prescribed to help relieve symptoms caused by seasonal, food and plant allergies, including mild and uncomplicated allergic skin reactions, such as hives or swollen tissue. This medication may also be used to help treat asthma. Customers may receive this drug under the name Periactin.We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer.

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4.5
Rated 4.5 out of 5 stars
35 Ratings
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Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

87% Positive

Effectiveness

96% Positive

Ingredients

96% Positive

Long-Term Benefits

88% Positive

15 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Andrea on Jan 11, 2026

Helps my cat

Mr. Tommy is diabetic and takes a pill for cancer treatment. This medication has helped him with his lack of appetite.

Mr. Tommy is diabetic and takes a pill for cancer treatment. This medication has helped him with his lack of appetite.

Rated 1 out of 5 stars
By Janet on Sep 15, 2025

Bitter to him

He takes all of his different meds goumd, mixed with a bisque, and dosing syringe...happily. not so much when I tried to add cyproheptadine. I could not risk

He takes all of his different meds goumd, mixed with a bisque, and dosing syringe...happily. not so much when I tried to add cyproheptadine. I could not risk developing an advertising to our dosing routine!

Rated 3 out of 5 stars
By Bonnie on Dec 1, 2025

Prescribed by my vet.

Didn’t seem to help Bones much and caused increased appetite/weight gain!

Didn’t seem to help Bones much and caused increased appetite/weight gain!

Rated 5 out of 5 stars
By Giorgnsimonsmom on May 12, 2025

Cyproheptadine HCL 4-mg tablet

I've used both cypro and mirtazapine before, and I definitely prefer cypro because the effects are only in the system for one day and in my experience, not as hard

I've used both cypro and mirtazapine before, and I definitely prefer cypro because the effects are only in the system for one day and in my experience, not as hard on the cats mood...meaning: when I've had cats on mirtazapine they were became aggressive, but not mean just yeowling, pacing, nervous like...and the medication is prescribed to last up to 72 hours sometimes. With cypro, you give it once a day, and it's out of their system by that night. It may or may not have an immediate effect, meaning it may impact your cat's appetite almost immediately, or it may be a more gradual effect that lasts throughout the day... my cats have had a more smooth experience, that being said,cyproheptadine is an antihistamine so your cat may nap some. I much prefer this to transdermal mirtazapine and its side effects.

Rated 5 out of 5 stars
By Tammey on Mar 24, 2025

Just what the doctor ordered

This antihistamine works quickly and very effectively to stimulate appetites. My ailing senior kitty with kidney issues really responds to this within about 15 minutes

This antihistamine works quickly and very effectively to stimulate appetites. My ailing senior kitty with kidney issues really responds to this within about 15 minutes - actually better than Mirataz, so it's certainly worth a try for an inappetent kitty

Rated 5 out of 5 stars
By Joanne on Jul 16, 2025

Delivery

Chewy is finally getting back to fast delivery. Good job!

Chewy is finally getting back to fast delivery. Good job!

Rated 5 out of 5 stars
By Robert on Jan 30, 2025

Great Price, It Works

It's generic -- it works. Cat responds and eats after about a half hour.

It's generic -- it works. Cat responds and eats after about a half hour.

Rated 5 out of 5 stars
By Sandra on Sep 15, 2024

Appetite Stimulant

I have tried many types of appetite stimulants to try to get my cat eating. This is the only one (1/2 tablet) when combined with Mirtazapine 2ML that has my cat

I have tried many types of appetite stimulants to try to get my cat eating. This is the only one (1/2 tablet) when combined with Mirtazapine 2ML that has my cat starting to eat on his own. I will have to up the dose at the end of the month to try to get him to eat more and more often on his own.

Rated 5 out of 5 stars
By Tracy13 on Nov 7, 2024
Top 25 Contributor

Good product

We bought this for our cat's chronic snotty nose and it really seemed to help. It was much cheaper than the vets office.

We bought this for our cat's chronic snotty nose and it really seemed to help. It was much cheaper than the vets office.

Rated 4 out of 5 stars
By diane on Apr 15, 2024

it's a prescription

What's not to like? It's the correct medicine that my vet prescribed. Okay, one thing not to like. I took a star off because it was shipped in a box that could

What's not to like? It's the correct medicine that my vet prescribed. Okay, one thing not to like. I took a star off because it was shipped in a box that could have fit dozens of items that size and there were only two. Minus one star for environmental irresponsibility. As for recommendation, ask your vet.