Cosequin - dog/general (updated files)

Olive Leaf Extract for Dogs: What You Need to Know

Olive leave extract should only be provided with a vet’s recommendation.
Olive leaf extract contains powerful antioxidants and other biologically active components.

Photo by megaflopp/Istock/Getty Images

Olive leaf extract is made from olive tree leaves. Rich in a compound called oleuropein, olive leaf extract has been studied in people for its ability to modulate inflammation, provide powerful antioxidants, and support healthy blood sugar and blood pressure. The research in dogs, however, is thinner. Because of its ability to interact with multiple body systems, it’s best to use olive leaf extract carefully and after your vet recommends it. 

Here is what the current research shows and whether vets recommend olive leaf extract for dogs.  

Key Takeaways

  • Olive leaf extract comes from olive tree leaves and contains compounds such as oleuropein and hydroxytyrosol.
  • Evidence for its effectiveness in dogs is limited, and most of what is known comes from studies in humans and rodents.
  • Olive leaf extract can interact with medications and may cause unwanted effects, so check with your veterinarian first.

How Does Olive Leaf Extract Work in Dogs?


Olive leaf extract contains a class of chemicals called polyphenols, including oleuropein and hydroxytyrosol. These have been studied for anti-inflammatory and antioxidant activity, as well as other biological effects including antimicrobial and the ability to modulate both blood sugar and blood pressure. 

Studies in humans have shown the extract can be absorbed and metabolized, and rodent and lab studies suggest positive effects on inflammatory and cardiovascular lab values. But these studies don’t necessarily translate to meaningful effects in dogs.  

Benefits of Olive Leaf Extract in Dogs


Based on human and rodent studies, some vets turn to olive leaf extract for varied benefits, including:  

  • Fighting bacteria and viruses that cause infection  
  • Modulating inflammation, which is linked to multiple diseases  
  • Providing a potent dose of antioxidants  
  • Providing additional support in dogs being treated for recurring skin and ear conditions 
  • Supporting healthy blood sugar and blood pressure levels   

It’s important to note, however, that few of these uses have actually been studied in dogs. Most of the claims regarding olive leaf extract are derived from studies in people, rodents, or cell cultures.

Potential Side Effects of Olive Leaf Extract in Dogs


Dog-specific safety data for olive leaf extract is lacking, so the side effects aren’t well-defined. However, anecdotal evidence suggests that olive leaf extract could cause digestive upset including vomiting and diarrhea, muscle pain, and allergic reactions among dogs who cannot tolerate it.  

Because of its biologic activity, olive leaf extract may also interact with medications for dogs with diabetes or high blood pressure. If your dog is pregnant or nursing, or has been diagnosed with diabetes, high blood pressure, kidney or liver disease, or allergies, it’s not recommended to provide olive leaf extract without the recommendation of a vet.  

If you are giving your dog olive leaf and notice any side effects or changes in behavior, stop the supplement right away and contact your vet. 

How to Give Your Dog Olive Leaf Extract


If your veterinarian recommends olive leaf extract, use a product made for dogs and follow your vet’s instructions and the product label. Don’t combine it with other supplements or medications unless your vet recommends doing so. 

What to Do If Your Dog Takes Too Much Olive Leaf Extract


If your dog gets more olive leaf extract than intended, contact your veterinarian, an emergency hospital, or Pet Poison Helpline (855-764-7661) right away. Have the product packaging available so you can relay information about the exact ingredients your dog got. 

If your dog is acting unusually sleepy, vomiting, having diarrhea, or seems a bit off after taking a supplement, don’t wait to see if it passes. Quick advice from a vet is the safest move. 

FAQs About Olive Leaf Extract for Dogs


Is olive leaf extract proven to help dogs? 

No. The strongest published evidence comes from studies performed on humans and rodents, so any use in dogs is based on indirect evidence.  

What is olive leaf extract, exactly? 

Olive leaf extract is a concentrated extract made from olive tree leaves, which contain bioactive compounds like oleuropein and hydroxytyrosol. These compounds have been studied for their anti-inflammatory, antioxidant, and other biological effects. 

Can I give my dog a human olive leaf capsule? 

Dogs shouldn’t receive human supplements without a veterinarian’s okay. Take the product bottle or ingredient list to your vet to see if they think it is appropriate for your dog. 

Should olive leaf extract replace my dog’s medication? 

No. Supplements are not intended to treat, cure, or prevent disease, so they should not be used as a replacement for prescription medications. 

Attributions


This article was created with assistance from AI tools. The content has been reviewed for accuracy and edited by a human. 

References 

  1. 1. Menezes RCR, Peres KK, Costa-Valle MT, et al. Oral administration of oleuropein and olive leaf extract has cardioprotective effects in rodents: A systematic review. Rev Port Cardiol. 2022;41(2):167-175. doi:10.1016/j.repc.2021.05.011. https://pubmed.ncbi.nlm.nih.gov/36062705/
  2. U.S. Food and Drug Administration. FDA 101: Dietary Supplements. Accessed April 14, 2026. https://www.fda.gov/consumers/consumer-updates/fda-101-dietary-supplements
  3. 10 Facts About What Fda Does And Does Not Approve. Accessed April 14, 2026. https://www.fda.gov/consumers/consumer-updates/10-facts-about-what-fda-does-and-does-not-approve
  4. Structure function Claims. Accessed April 14, 2026. https://www.fda.gov/food/nutrition-food-labeling-and-critical-foods/structurefunction-claims
  5. Dietary Supplements. Accessed April 14, 2026. https://www.fda.gov/food/dietary-supplements

Chewy Editors

Chewy Editors

Angela Beal, DVM

Angela Beal, DVM

Angela Beal is a veterinarian in Columbus, Ohio, who loves helping pet owners provide the best possible care for their beloved companions.