Frontline Shield Flea & Tick Treatment for Extra Large Dogs, 81 - 120 lbs, 6 doses (6-Month Protection)

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About This Item

Details

  • Helps kill ticks, stable flies, chewing lice and adult fleas, flea eggs and larvae.
  • Topical solution helps to repel ticks that may transmit Lyme disease and mosquitoes that may transmit heartworm disease.
  • Helps prevent reinfestation by stopping all flea life stages from developing.
  • Each dose is formulated to protect your dog for a full 30 days.
  • The treatment is easy to apply and is waterproof 24 hours after application.

Ingredients

Instructions

Size

FAQ

Learn More About Frontline Shield From Our Team of Experts

One-Spot Topical Application

Frontline Shield for Dogs is a topical solution that's available without a prescription. From a leading name in flea and tick protection, Frontline Shield is waterproof after 24 hours. 1 dose = 30 days of protection.

Flea, Tick, and Mosquito Facts

  • Fleas and ticks are a year-round threat.
  • They can be brought inside by people or dogs.
  • Fleas, ticks, and mosquitos can transmit harmful parasites and diseases.
  • Just one mosquito bite can spread heartworm disease, causing lifelong damage.

Proven 3-In-1 Protection

Frontline Shield has three active ingredients (permethrin, pyriproxyfen, and fipronil) that kiII fleas and ticks, inhibit egg and larval development of fleas, and repel ticks that may transmit Lyme disease and mosquitoes that may transmit heartworm disease.

How to Apply

Follow these simple steps for a correct and effective application:

  1.  Cut the tip of the pipette with a pair of scissors.
  2.  Part hair and apply on shoulder blades, completely emptying the pipette.
  3.  Leave the protection to spread through your dog's coat.

About Frontline Shield

Frontline Shield for Dogs is a 3-in-1 topical solution that kiIIs fleas and ticks, plus repels ticks that transmit Lyme disease and mosquitoes that transmit heartworm disease. Each dose lasts for 30 days, delivering the lasting protection your dog needs.

Shop Frontline Shield

Questions & Answers

5 Customer Questions


what ticks does this product kill

Answer by ChewyMar 08, 2021
This treatment is formulated to kill and repel all ticks.

my lab has fleas, how quickly will he get relief

Answer by ChewyJun 29, 2021
Starting 2 days after application, this treatment can start killing fleas in 5 minutes and ticks in 1 hour.

does this repel flies?

Answer by ChewyNov 12, 2021
This treatment Helps kill ticks, stable flies, chewing lice and adult fleas, flea eggs and larvae. The topical solution helps to repel ticks that may transmit Lyme disease and mosquitoes that may transmit heartworm disease. Helps prevent reinfestation by stopping all flea life stages from developing.

Does this topical treatment need a prescription?

Answer by ChewyAug 22, 2021
This treatment does not require a prescription.

4.3
Rated 4.3 out of 5 stars
150 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

80% Positive

Effectiveness

80% Positive

Ingredients

78% Positive

Long-Term Benefits

81% Positive

54 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 3 out of 5 stars
By Lori on Nov 30, 2025

Not much changed.

I didn't feel like this did much better than the Nexguard my doing is on. It was really sticky on her as well. She has nice soft fur and this made it feel dirty

I didn't feel like this did much better than the Nexguard my doing is on. It was really sticky on her as well. She has nice soft fur and this made it feel dirty.


Rated 1 out of 5 stars
By Denise on Sep 12, 2025

Did not work on him.

He still has fleas after two doses given to him. I was careful about using it correctly so I know it wasn't that I didn't put it on him right. It just did not work!

He still has fleas after two doses given to him. I was careful about using it correctly so I know it wasn't that I didn't put it on him right. It just did not work! I guess I'm got to find what does.


Rated 5 out of 5 stars
By Heather on Jan 5, 2026

Great product

Works great for my dogs,gives them no issues. Easy to apply.

Works great for my dogs,gives them no issues. Easy to apply.


Rated 1 out of 5 stars
By RescueMom on Nov 24, 2025

Dried their skin

All of my dogs were Left with extemely dry skin. One lost fur. Proceed with caution!

All of my dogs were Left with extemely dry skin. One lost fur. Proceed with caution!


Rated 5 out of 5 stars
By Rebecca on Aug 31, 2025

Frontline Shield Flea and Tick Treatment

The instructions were great. It was to apply. There were stickers to put on my calendar when I apply the flea and tick treatment.

The instructions were great. It was to apply. There were stickers to put on my calendar when I apply the flea and tick treatment.


Rated 3 out of 5 stars
By Daphne on Nov 13, 2025

Does great for fleas?

Using it from his neck down to his tail leaves his fur a mess

Using it from his neck down to his tail leaves his fur a mess


Rated 5 out of 5 stars
By ted on Sep 17, 2025

Frontline Shield

This product seems to be working well. We will keep our fingers crossed.

This product seems to be working well. We will keep our fingers crossed.


Rated 5 out of 5 stars
By Shelby on Jun 19, 2025

Works great!

We live in a more wooded area and this stuff works great! We only ever see 1 or 2 stray fleas. We have been using this for 2 years now and its our go to product

We live in a more wooded area and this stuff works great! We only ever see 1 or 2 stray fleas. We have been using this for 2 years now and its our go to product.


Rated 5 out of 5 stars
By Hmin on Jun 14, 2025

Good for Goats.

I have a goat that is allergic to ticks. Her skin melt when bit. I put this on all summer . You have to have the right weight for each goat.

I have a goat that is allergic to ticks. Her skin melt when bit. I put this on all summer . You have to have the right weight for each goat.


Rated 5 out of 5 stars
By Joe on Jun 24, 2025

Packaging was very appealing

The capsules I think are safe & sealed then just cut the tip off and apply.

The capsules I think are safe & sealed then just cut the tip off and apply.