Lactulose (Generic) Oral Solution, slide 1 of 1

Lactulose (Generic) Oral Solution, 10 g/15-mL, 16-oz

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Lactulose is a liquid medication prescribed to soften stools and manage the uncomfortable symptoms of constipation. It can also be used to help support animals who suffer from liver problems. Because it comes in a liquid form, it's easy to administer—simply add it to regular meals or give directly. Customers may receive this drug under the names Enulose, Cephulac, Kristalose.


Lactulose is used as a stool softener to help treat constipation. It has also been used in the treatment of liver disease to help prevent ammonia from building up in the blood.

Possible Side Effects

Diarrhea, loss of appetite, flatulence (increased gas), and cramping have been reported. Gastrointestinal side effects can subside with time. Other side effects may occur. An allergic reaction to Lactulose is possible. Your pet may experience swelling, listlessness, and shock if this occurs. If your pet appears sick in any way after receiving Lactulose, contact your veterinarian immediately. Let your veterinarian know if your pet produces less than 2-3 soft stools per day.

Drug & Food Interactions

Let your veterinarian know about any other medications or supplements your pet is taking before starting Lactulose. Some antibiotics, oral antacids, and other laxatives may interact with Lactulose. Other drug interactions are possible.


This medication should not be used in pets who are hypersensitive to Lactulose. Lactulose may also alter insulin requirements in diabetic pets.

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer.

  1. Prescribing Information

See all items by Lactulose

  • Item Number
  • Generic Name
  • Common Brand Name(s)
    Enulose, Cephulac, Kristalose
  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
    Digestive Issues, Liver Disease
  • Drug Type

Lactulose, Lactose, Sodium Hydroxide, Purified Water.

Recommended Dosage

Use this medication as directed by your veterinarian. If you forget a dose, give it as soon as possible but do not give two doses at the same time.

Storage Instructions

Store at controlled room temperatures of 59° - 86°F. Avoid excessive heat.


What is Lactulose?

This is an oral medication that is used to help manage constipation in cats and dogs. It can also be used to help support pets who suffer from liver problems.

What are the benefits of Lactulose?

  • Liquid formulation allows for easy administration.
  • Softens stools to help ease constipation.
  • Can assist in the management of feline megacolon.
  • Helps reduce chances of hepatic encephalopathy in pets with liver disease.

How is this medication given?

Give this medication by mouth exactly as directed by your veterinarian.

Lactulose is a liquid medication so It may be easiest to deliver it to your pet using a syringe. Some animals may not like the taste of Lactulose (especially cats).

If you are not sure how to give this medication properly, contact your veterinarian for further instructions.

How does this medication work?

Lactulose is the active ingredient that helps to draw water into the stool which helps to increase volume and works to make each stool softer and easier to pass. Lactulose can also prevent the absorption of ammonia from the gut so it can be helpful in the management of liver disease.

What results can I expect?

Lactulose is effective in softening the stools in pets who suffer from constipation. Pets using this medication should pass 2-3 soft stools per day.

Symptoms can return if medication is discontinued.

Rating: 4.2 of 5 stars 8 Reviews 8 Reviews 4.2 out of 5 Stars

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Rating: 4.2 of 5 stars 4.2 / 5

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8 Reviews

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  • 5 out of 5 stars

    Works very well!

    By on

    My boy will have to take this apparently forever for a mega colon issue. Am so thrilled he will take it in his food. Originally I was measuring in a syringe which was a mess getting the right amount, then pulling apart the syringe, washing it all... and the syringes don't last. Tested how many drops it would take to get the required dosage by measuring the cc's vs drops in teaspoon. Now instead of all that syringe agony I just use the original dropper type bottle from the vet and put the correct number of drops right into the food. No mess and no trouble seeing how much through the dark bottle. Hope this helps!

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  • 5 out of 5 stars

    Great Product

    By on

    Our cat Zoey was diagnosed with mega colon and our vet put her on 2 ML twice a day for life. I fill a tiny Rubbermaid container and fill the syringe from that. Giving Zoey a syringe twice a day didn't go well. I put it on her soft food twice a day. She loves it. We love our pets!

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  • 1 out of 5 stars

    Never worked and cats hate it

    By on Top 500 Contributor

    I paid $80 at vet for this and my cat still had 2 surgeries for blocked colon. Benefiber or mirilax works better. I had this from vet for 3 cats past few years, it never worked.

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  • 5 out of 5 stars

    You can use a tiny spoon to dispense this stuff

    By on

    I give my cats 1 or 2 doses per day and they don't get constipated - it's excellent. Instead of fiddling with a dropper, use a tiny baby spoon (smaller than a teaspoon). Measure 1 ML dose into the spoon, which will fill one tiny spoon. A spoon is easier to clean, just pour slowly from the bottle, then wipe the bottle so it doesn't get sticky.

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  • 5 out of 5 stars

    Such a price difference

    By on Top 25 Contributor

    This really helps my older guy and is tons cheaper on Chewy. Only thing that would make it better would be to change the top to allow for syringe. Otherwise the syringe gets all sticky and can get on the cats fur which is a mess

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  • 4 out of 5 stars

    "Elvis" approves.

    By on

    my little 4lb chihuhua "Elvis" was diagnosed with portysystemic shunt (unfortunatley surgery is $$$$) so he needed this medication along with prescription food...he very much likes the flavor of this and i haven't had any problems with him taking as directed...

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  • 4 out of 5 stars

    Great solution for regular subscription

    By on

    My cat will require daily lactulose for life. Getting her on a mail order prescription is a great time saver for me. One gripe about this brand is that it does not have a stopper or guide (not sure what it's called) for use with a needless syringe, so you have to dip the syringe into a dark bottle to get the medicine. Creates mess and possible contamination.

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  • 5 out of 5 stars

    great value

    By on

    My kitty also must take this for life. To the lady above who wishes it came with a rubber top for filling the syringe - any drug store has a plastic insert you can purchase.

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