Ondansetron (Generic) Tablets, slide 1 of 1

Ondansetron (Generic) Tablets

Prescription Item

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Strength: 8-mg
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Count: 1 tablet

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Ondansetron is an antiemetic drug used to treat or prevent severe vomiting in dogs and cats. While the FDA has approved it only for use in humans, veterinarians may prescribe it in certain situations. It is usually well tolerated by pets and can be given with or without food. Ask your veterinarian if ondansetron is right treatment for your pet.


Ondansetron is an antiemetic used for severe vomiting in dogs and cats. Ondansetron can be particularly effective for treating chemotherapy-associated vomiting.

Possible Side Effects

Ondansetron appears to be well tolerated in animals.

Drug & Food Interactions

Ondansetron is contraindicated in patients hypersensitive to it or other agents in this class. Ondansetron may mask ileus or gastric distention; it should not be used in place of nasogastric suction.


Use with caution in patients with hepatic dysfunction, as absorption may be increased because of reduced first-pass metabolism, and half-life may be prolonged; dosage adjustment may be warranted in severe hepatic impairment.

  1. Prescribing Information

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  • Item Number
  • Generic Name
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  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
  • Drug Type


Recommended Dosage

Consult with your veterinarian on recommended dosage

Storage Instructions

Store between 36 and 86 F


How is this medication useful?

Ondansetron is used to treat and/or prevent severe vomiting in dogs and cats. The FDA (U.S. Food & Drug Administration) has approved this drug for use in humans, but it is not officially approved for use in animals. The FDA allows veterinarians to prescribe products containing this drug in different species or for other conditions in certain situations. You and your veterinarian can discuss why this drug is the most appropriate choice.

How long until I will know if this medication is working, and how long will the effects of this medication last?

This medication should help your pet feel better within 1 to 2 hours. Your animal's clinical signs should improve after that time. The effects of this medication are short-lived, meaning they will stop working within 24 hours, although the benefits may be prolonged if your pet has decreased kidney and/or liver function.

Rating: 4.3 of 5 stars 6 Reviews 6 Reviews 4.3 out of 5 Stars

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83% Recommend

83% of reviewersrecommend this product

Rating: 4.3 of 5 stars 4.3 / 5

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6 Reviews

Showing 6 Reviews

  • 5 out of 5 stars

    Cheap, small, effective

    By Lizzie on Mar 8, 2021

    These are the mini ondansetron tablets. Very easy for cats to swallow. As of March 2021 this is the cheapest price for the medication with shipping.

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  • 1 out of 5 stars

    Not working

    By JustMe on Nov 4, 2020

    These are having no effect on the (presumed nausea and) vomiting caused by my 16 y.o. cat's Stage 3 kidney failure; so, unfortunately, any time I can get him to eat, he still regurgitates everything, and violently so.

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  • 5 out of 5 stars

    Chewy is reliable and really the best!

    By Chewy on Oct 22, 2020

    Always get my orders fast. They are always accurate and they provide the best customer service out of any company I've used! Thanks for making things easier Chewy!

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  • 5 out of 5 stars

    Best Serviced

    By Pumpkin on Jun 29, 2020

    The turnaround time for this order was especially quick Chewy is always very dependable for food supplies and the many products I have ordered over the yearsThank you Chewy

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  • 5 out of 5 stars

    Good stuff!

    By generic on Jul 29, 2020

    Despite having to mail a script in, I received the medication quickly. It works very well for fiona.

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  • 5 out of 5 stars

    Prescription Meds

    By Betsy on Mar 16, 2020

    Chewy is an awesome company! Love them! Quick response with contacting Vet for Rx for my puppy!

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