PANCREPLUS Powder for Dogs & Cats, 12-oz -

PancrePlus Powder for Dogs & Cats

By PancrePlus
Rated 2.8116 out of 5 stars
Prescription Item
Size: 12-oz
Size: 12-oz

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$289.77Chewy Price
$275.28Autoship Price
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Medications ship separately. Delivery times may vary.

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About This Item


PancrePlus is prescribed as a digestive aid and replacement therapy for those who have exocrine pancreatic insufficiency (EPI). EPI makes it hard or impossible for the body to digest proteins, carbohydrates and fats because the pancreas isn't producing the enzymes it should. This powder should be added to regular meals to aid in normal digestion.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Play Video: Learn More About PancrePlus From Our Team of Experts
Learn More About PancrePlus From Our Team of Experts

ReviewsWrite a Review

Rated 2.8116 out of 5 stars
69 Ratings
Would recommend to a friend

69 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Mamey on Apr 4, 2023

Too costly and granular

The sudden price increase was astronomical! So I switched to another enzyme product with Chewy at almost 1/3 the cost. Also, my cat was not eating her food with these enzymes so she lost weight. I figured out she did not like the consistency of this product with the larger granules. The new enzyme powder is pulverized more to a finer powder and she is eating again!

Rated 4 out of 5 stars
By luckydog1 on Apr 21, 2023

Amazing but pricey

Only trustworthy brand recommended by my vet and it 100% works for my dog! She was diagnosed with EPI. However, due to the high cost I have to alternate between this one and another brand that is cheaper. The high price is the only reason why I give it 4 stars instead of 5.

Rated 2 out of 5 stars
By Celisse on Feb 15, 2023

Lifesaving, Chronic Med TRIPLES in Price

My dog was diagnosed with EPI in October of 2020. In addition to the instability of the pandemic at the time, spending thousands to determine the true cause of my dog's illness, and then food changes the cost of this medicine has almost tripled in the last 2.5 years. In October of 2020, it was $110. Now it's almost $300. This medicine is necessary for my dog to live and it's disgusting a company would increase the price so drastically with zero explanation. I've asked my vet for an alternative and he stated he was hesitant because this medicine was the most effective. I will be reaching out to the company directly.

Rated 5 out of 5 stars
By MELO4721XI on Apr 30, 2023

Customer Service, I'm so grateful!

Thank you, Customer Service, for all the help in getting PancrePlus to us, so quickly! A bad situation got turned around, Hunter is doing really well, now.

Rated 5 out of 5 stars
By Tikka3320 on Apr 20, 2023

EpI Medicine

Can't believe the price increase, I have a German Shepard that does SAR, I have to pay this just to keep her healthy so she can rescue people.

Rated 1 out of 5 stars
By Jessica on Jan 30, 2023

Excessive price increase

Like so many others, I must look for an alternative to this medication/supplement that my German Shepherd needs for the rest of his life. We started using this in November of 2022 and paid $181.79 for the 12 oz. Now the price is $289.77 in January of 2023. I found an alternative on Chewy but do not know if it will work as well. I also reached out to the company: Neogen Corporation and inquired about their reasoning for such an excessive increase. I would encourage all of you dealing with this increase to send them an email so they are aware of the impact. If possible I will update if/when they respond.

Rated 1 out of 5 stars
By Rescuerof250 on Jan 18, 2023

costs are robbery

Yes this is the staple, “go to” product but the significant jump in price without any warning has left me, as a rescuer, scrambling to keep my rescued shepherd alive. He is a success story because of this product, and now it is priced outside of our budget. I’ve personally taken this dog from an ill 45 lbs to a healthy and happy 80 lbs, but is it fair to keep him up on this expensive product that has skyrocketed in costs overnight at the expensive of nine other rescued animals that need my financial support? This price jump has left me in a moral dilemma. I love this dog and he deserved to live a healthy life. There should be caps by the government on human and animal prescription products not to exceed more than a 15% price increase per year. That is humane.

Rated 1 out of 5 stars
By Christina on Jan 30, 2023

Outrageous price increase!

I have had this on autoship for years for my EPI dog. The product has worked great, but the price just continues to rise! This last proce increase was just outrageous! Almost $100 more than the last time I ordered! This is necessary for some animals to digest and absorb the nutrients from their food. It's a necessity, but not many people can pay the insane price for it. I have been a faithful customer and spend hundreds of dollars with chewy every month, but I will be searching elsewhere for another enzyme with a realistic price.

Rated 1 out of 5 stars
By HeavenlyDawn on Feb 17, 2023

Price Increase is Outrageous

I had to find another brand that wasn’t so expensive. So sad the company that makes this powder is taking advantage of its customers. I found a different brand and was able to buy 2 12 oz bottles for the price of this one bottle . On a side note I love chewys and know this is not their fault because the price for this brand is the same on multiple different websites.

Rated 1 out of 5 stars
By Jacks on Feb 24, 2023

Chewy is toooo high

I just called my vet to see what they charge for a 12 oz bottle and they told me 172.00. It looks like Chewy is making quite a profit. I paid 172.00 the last tiime I ordered this with Chewy and now they are 289.00.