PancrePlus Tablets for Dogs & Cats, 425-mg, 1 tablet

Prescription Item

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PancrePlus is prescribed as a digestive aid and replacement therapy for pets whose digestion of proteins, carbohydrates and fats are affected by exocrine pancreatic insufficiency (EPI).


For use as a digestive aid in replacement therapy where digestion of protein, carbohydrate and fat is inadequate due to exocrine pancreatic insufficiency.

Possible Side Effects

Some pets may exhibit reactions, such as allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), diarrhea or loose stool. If you observe any of these side effects, contact your veterinarian as soon as possible.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting this medication.


Discontinue use in animals with symptoms of sensitivity.

This product has recently undergone a packaging and formulation change by the manufacturer but maintains the same safety and efficacy.

Also available in a powder.

  1. Prescribing Information

See all items by PancrePlus

  • Item Number
  • Common Brand Name(s)
    PancrePlus, PanaKare Plus
  • Generic Name
    Pancreatic Enzyme Concentrate
  • Dosage Measure
    Use according to your veterinarian's instructions.
  • For Use With
    Dogs & Cats
  • Brand
    Vet One
  • Product Form
  • Health Condition
    Pancreatic Insufficiency Disorder (PID)
  • Drug Type

Lipase, Protease, Amylase

Recommended Dosage

Dogs: 2/3 tablets per meal. Cats: 1/2 - 1 tablet per meal. The dose is administered before each meal. Estimate dose according to the severity of the condition and weight of the animal.

Storage Instructions

Store tightly closed container in a dry place at room temperature.


What is PancrePlus?

PancrePlus is used as a digestive aid in replacement therapy where digestion of protein, carbohydrates and fat is inadequate due to exocrine pancreatic insufficiency.

What are the benefits of PancrePlus?

  • Enzyme replacement therapy to improve quality of life for pets with deficient exocrine pancreatic secretions.
  • Can be used for dogs and cats.
  • FDA approved.

How is this medication given?

For dogs, mix 3/4 to 1 teaspoon with each meal. For cats, mix 1/4 to 3/4 teaspoon with each meal. Mix well with moistened food (canned or dry) and leave at room temperature for 15-20 minutes prior to feeding. Give this medication exactly as directed by your veterinarian.

How does this medication work?

PancrePlus contains pancreatic enzymes which help to digest fat, protein and sugars. It is mixed with food prior to each meal.

What results can I expect?

Improves quality of life for pet's suffering with deficient exocrine pancreatic secretions.


Customer Reviews

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  • 5 out of 5 stars

    Exocrine Pancreatic Insufficiency

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    This enzyme has worked very well for my German Shepherd. He was starving, and now is of good weight.

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