Spironolactone (Generic) Tablets, slide 1 of 1

Spironolactone (Generic) Tablets

Prescription Item

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Strength: 25-mg
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Count: 1 tablet
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Spironolactone is a prescription diuretic used to treat congestive heart failure and fluid accumulation in the abdomen. It works to lessen tissue fluids without a corresponding loss of potassium. This easy to administer uncoated tablet may be hidden in a pill pocket as a treat. Customers may receive this drug under the name Aldactone.

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Used to manage symptoms associated with hypertension (high blood pressure), heart failure, dilated cardiomyopathy, kidney disease and other types of heart diseases.

Possible Side Effects

Please contact your veterinarian immediately if you notice any of the following reactions: dehydration with excessive thirst and decreased urine production or electrolyte imbalances (e.g., high potassium and low sodium), often with weakness, stumbling, lack of energy, vomiting or diarrhea.

Other side effects, like an allergic reaction, are also possible. Contact your vet at once if your pet is acting ill in any way after taking this medication.

Drug & Food Interactions

Notify your vet of any other medications, including vitamins and supplements, your pet is taking while receiving Spironolactone. Aspirin may decrease the effects of Spironolactone. Interactions are possible when Spironolactone tablets are used along with vasodilators (drugs that open blood vessels) or non-steroidal anti-inflammatory drugs.

The dosage of diuretic medication, such as furosemide (diuretic) may need to be altered when it is given with Spironolactone tablets. Other drug interactions may occur.


Spironolactone will cause your pet to urinate more often. Your pet may have more accidents. Your pet needs to eat and drink well while taking this medication or the risk of side effects increases. Contact your veterinarian if your pet is not eating or drinking well, or is vomiting, has diarrhea or becomes lethargic. Do not discontinue the medication unless directed.

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer. Please note product may arrive in a Chewy Pharmacy vial.

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  1. Prescribing Information

See all items by Spironolactone

  • Item Number
  • Generic Name
  • Common Brand Name(s)
  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
    High Blood Pressure
  • Drug Type


Recommended Dosage

Use as directed by your veterinarian.

Storage Instructions

Store at or below 77°F. .


What is Spironolactone Tablets?

A diuretic used to treat congestive heart failure and fluid accumulation in the abdomen (ascites).

What are the benefits of Spironolactone Tablets?

  • Often effective when other diuretic treatments don't work.
  • Does not cause potassium loss .
  • Easy to administer .

How is this medication given?

Spironolactone is given orally. Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.

Food may increase the absorption of Spironolactone. Consult your veterinarian about giving this medication with food.

This medication should only be given to the pet for whom it was prescribed. This medication is given by mouth and can be given with or without food. Never stop giving Spironolactone Tablets suddenly unless your veterinarian instructs you to. Always speak to your veterinarian if you have questions about how to give this medication.

How does this medication work?

Spironolactone Tablets increases the excretion of water by the kidneys.

What results can I expect?

Spironolactone will not cure a disease, but will help manage the symptoms. It may take several days for the spironolactone to have its maximum effect. The drug must consistently be given according to your veterinarian's directions to have the full effect.

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