As a horse parent, keeping your equine friend’s joints healthy is a number one priority for you, especially if she has osteoarthritis. Surpass Topical Cream for Horses offers you an FDA-approved way to do just that. Formulated in an easy-to-use to cream, the Surpass Topical Cream for Horses works to help ease the pain and inflammation associated with osteoarthritis in your horse’s hocks, knees, fetlocks, and pastern joints. This topical cream for horses doesn't just modify the symptoms of osteoarthritis, it also modifies the disease itself. Surpass penetrates the skin barrier, targeting relief at the site of joint pain and inflammation. Helping to keep your horse’s joints happy and healthy will help keep her feeling fit as a filly.
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SURPASS (1% diclofenac sodium) Topical Anti-Inflammatory Cream is indicated for the control of pain and inflammation associated with osteoarthritis (OA) in tarsal, carpal, metacarpophalangeal, metatarsophalangeal and proximal interphalangeal (hock, knee, fetlock and pastern) joints in horses. Unlike most alternatives, SURPASS is applied only twice daily, a much more effective use of your time and effort. Unlike most alternatives, SURPASS is applied only twice daily, a much more effective use of your time and effort.
Possible Side Effects
Adverse reactions associated with NSAIDs may include: weight loss, colic, diarrhea, or yellowing of the gums, skin, or whites of the eyes (jaundice). Serious adverse reactions associated with this drug class can occur without warning and, in rare situations, result in death. Discontinue the use of SURPASS (1% diclofenac sodium) Topical Anti-Inflammatory Cream and contact your veterinarian immediately if these signs are observed. The majority of patients with drug-related reactions recover when the signs are recognized, drug administration is stopped, and veterinary care, if appropriate, is initiated. Adverse reactions during the safety study included a gastric ulcer in one horse that received 5.6x the recommended dosage, diarrhea and uterine discharge in one horse that received 2.8x the recommended dosage, and weight loss in four of the six horses in the 5.6x dosage group.
Drug & Food Interactions
Pease consult with your veterinarian for any Food and Drug interaction concerns.
Exceeding the recommended dosage or treating multiple joints may increase plasma concentrations of diclofenac. The systemic effects of excess diclofenac doses that exceed the recommended label amount and duration have not been evaluated.
As a class, NSAIDs may be associated with gastrointestinal and renal toxicity. When NSAIDs inhibit prostaglandins that cause inflammation, they may also inhibit prostaglandins that maintain normal homeostatic function. These anti-prostaglandin effects may result in clinically significant disease in patients with underlying or preexisting disease more often than in healthy patients. Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with renal, cardiovascular and/or hepatic dysfunction.
Horses should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. Owners should be advised to observe for signs of potential drug toxicity.
Studies to determine the effect of SURPASS (1% diclofenac sodium) Topical Anti-Inflammatory Cream when administered concomitantly with other drugs have not been conducted. Since many NSAIDs possess the potential to induce gastric ulceration, concomitant use of SURPASS cream with any other anti-inflammatory drugs, such as other NSAIDs and corticosteroids, should be avoided. Drug compatibility should be monitored closely in patients receiving adjunctive therapy.
SURPASS topical cream is contraindicated in animals with known hypersensitivity to diclofenac.
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