VetriScience GlycoFlex Plus Joint Support Bite-Sized Dog Chews
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The GlycoFlex Plus joint supplement for dogs provides clinically proven nutritional joint support for working dog breeds, competitive dogs, and senior dogs. This advanced joint support supplement is suitable for dogs of any age, and is clinically proven to increase hind leg strength up to 41% in just four weeks. Glyco Flex Plus maintains comfort and mobility in dogs, and includes more active ingredients than other leading brands for maximum nutritional absorption and effectiveness.
Key Benefits- Clinically proven supplement containing glucosamine, chondroitin, MSM, antioxidants, plus perna mussel for medium and large dogs
- Up to 41% increase in hind leg strength in just 4 weeks
- Delicious duck-flavored chew is recommended for dogs of all ages needing advanced joint support
- Powerful combination of ingredients helps cushion joints, promote cartilage building and alleviate discomfort caused by normal daily activities
- National Animal Supplement Council (NASC) seal of approval so you know you’re buying a product developed to quality standards
Safe use in pregnant animals or animals intended for breeding has not been proven. If lameness worsens, discontinue use and contact your veterinarian.
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Item Number90404
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LifestageAdult, Senior, Puppy
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Breed SizeSmall Breeds, Medium Breeds, Large Breeds, Extra Small & Toy Breeds, Giant Breeds, All Breeds
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Food FormSupplement
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Product FormSoft Chew
Active Ingredients: Glucosamine Hci (Shrimp and Crab), Perna Canaliculus (Glycoomega Brand Green-Lipped Mussel), Chondroitin Sulfate (Porcine), N,N-Dimetylglycine Hci (D mg), Dl-Alpha Tocopheryl Acetate (Vitamin E), Ascorbic Acid (Vitamin C), Manganese (Mn Proteinate), Grape Seed (Vitis Vinifera) Extract, L-Glutathione, Selenium (Na Selenite).
Inactive Ingredients: Arabic Gum, Brewers Yeast, Calcium Sulfate, Canola Oil, Citric Acid, Citrus Pectin, Duck Flavor, Glycerin, Maltodextrin, Mixed Tocopherols, Propionic Acid, Rosemary Extract, Silicon Dioxide, Sodium Alginate, Sorbic Acid, Soy Lecithin, Vegetable Oil, Water.
Weight | Directions for use (4-6 weeks) | Maintenance (after initial period) |
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31 lbs-60 lbs | 2 chews/day | 1 chew/day |
61 lbs-100 lbs | 4 chews/day | 2 chews/day |
101 lbs | 5 chews/day | 3 chews/day |
If giving more than 1 soft chew daily, divide between AM and PM.
Why should I include vitamins & supplements in my pet’s diet?
Most commercial pet foods include baseline vitamins and nutrients, but some may not have the adequate amount to suit your pet’s exact health needs. Like in humans, vitamins and supplements can help support your pet’s long-term health, regulating everything from digestion to muscle growth. Consult your veterinarian to determine the best vitamins and supplements for your furry friend.
How often should I give this supplement to my pet?
It is recommended to give the suggested dosage based off your pet’s weight. Please refer to the Feeding Instructions tab and consult with your veterinarian for more information.
Is this supplement safe to use with the medication my pet is currently taking?
If your pet has a medical condition and is taking other medication, we recommend consulting with your veterinarian to ensure that this supplement is safe to use.
My pet is allergic to certain ingredients, will this product be safe to use?
For a complete list of ingredients, click on the 'Nutritional Info' tab, next to the 'Description' tab, just under the product photos. If you are unsure about the safety of this product for your pet, we recommend consulting with your veterinarian.
Does this product come in other product forms?
For a complete assortment of products by the manufacturer of this supplement, click on the link next to the item name at the top of the page. You can also find an assortment of supplements across all product forms on our page.

Clinically Proven Joint Support
GlycoFlex gives your dog comprehensive joint support for mobility, flexibility and everyday comfort in the form of a delicious treat that she'll actually want to eat. Available in both tablets and bite-sized chews, GlycoFlex is recommended by veterinarians to provide joint support at every stage of your pet's life.


Formulated to Support a Lifetime of Healthy Joints
GlycoFlex 1 s a great proactive joint supplement for growing and active dogs.
GlycoFlex 2 has higher levels of glucosamine and is recommended for adult or maturing dogs.
GlycoFlex 3 is an extra-strength formula for dogs in need of maximum joint support.
GlycoFlex Classic is an introductory hip and joint health supplement that supports proper joint and connective tissue growth and function in dogs of all ages.
GlycoFlex Plus provides advanced support to help cushion joints, promote cartilage building and alleviate discomfort caused by normal daily activities.
Time-Tested Ingredients
GlycoFlex uses time-tested active ingredients to provide support for joint mobility, flexibility and overall comfort. Perna canaliculus, or green-lipped mussel, is found in every formula to help maintain healthy connective tissue. Glucosamine helps build healthy cartilage, and MSM is included as a necessary ingredient for forming connective tissue in the joints.

About VetriScience
As the makers of GlycoFlex and an extensive line of pet supplements, VetriScience Laboratories is a leader in the pet health industry. For over 40 years, VetriScience has led the way by providing exceptional and innovative supplements created for the health and well-being of companion animals. They are committed to using only pure and highly researched ingredients to produce quality products that are safe and effective.

Customer Reviews
90% Recommend
90% of reviewersrecommend this product
You've Already Reviewed This Item
108 Reviews
Showing 1-10 of 108 Reviews
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So far, so good
By Candy on Nov 18, 2020
My dog loves these chews and so far, she's doing well on them. It hasn't been a full month yet, so it may me too soon to truly tell if this product really works. She is still quite mobile, but vet says she does have arthritis in her hind legs. I'm praying GlycoFlex will be a keeper. I do wish it didn't have maltodextrin as one of the ingredients. It's pretty high on the glycemic index.
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Seem to work well but stink
By sarah on Dec 24, 2020
I bought 2 packs of these this one for my large dog and one for my small dog. These ones have a terrible smell and make my dogs breath horrible. The small dog ones don't stink, they seem to work well but the smell is awful.
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Amazing Supplement
By Mykidshavepaws on Jan 9, 2021
This product has been wonderful for my dog with torn ACL's. We have these chews as recommended and she has become more active. She is also showing more of a puppy like behavior. Highly recommended.
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Stinky Chews
By MamaLu on Dec 30, 2020
I had to buy these joint support chews because my regular chews were out of stock. While my dogs do eat them, I can hardly stand the smell of them when I open the package!
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Halo Approved
By TPayne on Sep 12, 2020
Our Irish wolfhound is a senior at 8.5 years old, and will eventually need more assistance with her hind end. We're trying the GlycoflexPlus due to its claims of increasing mobility. I was concerned about the potential for an off-putting smell, but it isn't nearly as bad as the PillPocket duck & pea. Halo co.es from the other room when she hwars the bag, so far it's 2 paws up from her. Currently giving 4 stars until longer duration to see improvement.
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First Impression
By DVan on Aug 18, 2020
I've only been using the product for about a week, so I can't review the effectiveness as of yet, but my first impression is I just can't get past the smell of this product. My dog will eat anything, so that's not an issue, but if you have a finicky eater this may be a problem for you. I would definitely say spend the extra money to get one of their products in a different flavor because the duck flavor smells absolutely awful. I'm just hoping that I see some results and it's worth it!
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She thinks it is a treat!
By Nara108 on Jul 6, 2020
My older chocolate lab loves these. She gets a few other supplements with her kibble and she always eats this first. Of course, she is a lab! But they have helps her with her Arthritis and she is walking up the stairs better. So I am happy if she is happy.
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Great as a treat but rough on belly
By Erika on Jul 24, 2020
Gave my 6 yr old golden lab these to improve his hind legs. He enjoyed eating them but after a week, they upset his belly and gave him colitis. They didn’t effect my 2 yr chocolate though.
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Arthritis pain lessened
By Glycoflex on Sep 2, 2020
Has seemed to help our 8yr old lab's movement and she loves it. Four a day and she's friskier and seems happy.
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Very good supplement
By Msladybuggg on Sep 9, 2020
Gave these to my senior arthritic husky, they seemed to help her move about a little smoother.