Vet's Best Flea & Tick Spot Treatment for Dogs, Over 40 lbs, 4 Doses (4-mos. supply)

By Vet's Best
Rated 3.5 out of 5 stars
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Vet's Best Flea & Tick Spot Treatment for Dogs, Over 40 lbs, 4 Doses (4-mos. supply) slide 1 of 6
$9.84Chewy Price
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About This Item

  • Kills and repels fleas and ticks by contact for up to one month for large dogs over 40 lbs and who are 12 weeks or older.
  • The supplied dropper applicator makes this solution easy to apply. Simply squeeze the specified amount between your pet's shoulder blades and at the base of the tail.
  • This natural formula is crafted with a unique blend of certified natural oils, including clove, thyme and cinnamon oils.
  • Formulated for dogs and puppies 12 weeks or older when used as directed.
  • Manufactured in the USA with quality domestic and internatially sourced ingredients.
Play Video: Learn More About Vet's Best From Our Team of Experts
Learn More About Vet's Best From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

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Top IngredientsClove Oil 7.5%, Thyme Oil 2.5%, Cinnamon Oil 2.5%...Permethrin: 45%, S-Methoprene: 3%, Other Ingredients: 52%.Clove Oil 7.5%, Thyme Oil 2.5%, Cinnamon Oil 2.5%...Permethrin: 45%, S-Methoprene: 3%, Other Ingredients: 52%.
LifestageAdultAdultAdultAdult, PuppyAdult, Puppy
Breed SizeLarge BreedsLarge Breeds, Giant BreedsExtra Small Breeds, Small BreedsExtra Small Breeds, Small BreedsMedium Breeds

Questions & Answers

3 Customer Questions

Is it waterproof
Answer by ChewyAug 08, 2021
This treatment is waterproof however, you should always wait at least 24 hours before bathing or swimming.

Does this help prevent mosquitos in addition to fleas and ticks?
Answer by ChewyAug 15, 2022
This only repels and kills fleas and ticks.

will this work on dogs 180 pounds
Answer by ChewyMay 09, 2022
This flea and tick treatment is suitable for dogs over 40 pounds. It is suitable for dogs over 100 pounds.

ReviewsWrite a Review

Rated 3.5 out of 5 stars
14 Reviews
Would recommend to a friend

14 Customer Reviews

Rated 3 out of 5 stars
By VetsBest on Aug 13, 2022

Vets Best Spot On

I will have to apply to my dogs in the 2 week period it did not last a full month it smells pleasant and I can use it with the flea away so I do not have to give the dogs flea away everyday just once a week or 1/2 the dose of flea away twice a week along with the vets best spot on

Rated 1 out of 5 stars
By jenb on Aug 12, 2022


The product came with one empty vial it leaked to all through our package I'm in the process of contacting chewy... Besides that I love that the product is more on the natural side and I love the scent

Rated 5 out of 5 stars
By Kelly on May 11, 2022

It actually works!

We're in prime tick season in New Hampshire and they're bad this year, and I'm impressed. No engorged ticks on our dogs, will only find some in the ear area on our bigger dog or crawling off them and honestly with how bad the ticks are here that's normal no matter what we use. The smell is strong so I'd recommend having them outside for an hour or so right after putting it on, but the smell is definitely worth it knowing my dogs aren't getting Lyme disease or tapeworms from fleas. I love that there's a more natural alternative that works!

Rated 5 out of 5 stars
By Blessed on Jul 21, 2022

Wonderful product

Love the natural flea med. My four legged baby feels wonderful and smells great.

Rated 4 out of 5 stars
By Nyflyboy on Nov 30, 2021

Not perfect, but a lot safer then using toxic chemicals...

I've used Vets Best for 2 yrs on my English Setters and it seems to work well against fleas, but ticks are a different story. We have a plague of ticks in rural NY and they are at their worst in early spring and fall. I can't even walk my girls down the road, without a tick latching on. Vet's Best spot treatment, spray and shampoo, when combined are a good deterrent against them. Yes, the smell is strong for a day or two, so I put the spot on prior to our 2 mile walk and it's dry by the time we're back home. You should do a tick check after your dog is outside, to remove any possible hitch hikers from getting into your home. They'll drop off once they smell the spot on. I got away from the toxic chemicles, because one Setter was having constant seizures. Now she hasn't had any. If your dog has white fur, expect to see a slight yellowish color where it's applied. It's no big deal, it fades in time. Though it's a little more work, I'll never use commercial drops, oral meds or collars on my dogs again.

Rated 2 out of 5 stars
By SBee on Apr 14, 2022

Messy flea and tick

My dogs cost is white I put on as directed his coat turned bright yellow

Rated 2 out of 5 stars
By Chrissy on Dec 10, 2021


I love vets best smells great leaves my pets soft but this is supposed to work for a month with each dose. It worked for two days and my dogs are infested again. Looks like I have to get frontline. I will not be getting this product from this brand again.

Rated 2 out of 5 stars
By Scout on Nov 13, 2021

Doesn’t really work

We had a bad case of fleas and decided to try this along with a bunch of other things to get rid of them. This didn’t really work. The first application seamed to work for maybe two weeks then we reapplied after three weeks and not only did it do nothing for the fleas the second time but we also found a tick on her just a few days after the second application

Rated 5 out of 5 stars
By Stanky111 on Sep 27, 2021

Good smell and hopeful

We only use this product once but it smells like fall (cloves) and we are hopeful that it will prevent fleas and ticks maybe mosquitoes too if we are lucky. This is a much safer alternative to the topical chemicals or even worse the seizure enduring ingestible. It didn’t seem to bother my dogs coat nearly as much as the chemical topical normally does.

Rated 5 out of 5 stars
By Monica on Jul 2, 2021

Great product

We had used Frontline on my dog for years until he developed a seizure disorder. We combed through everything we were putting on or in him, and eventually decided to switch off of the harsh chemicals of topical flea & tick meds onto this more natural product. We have been using this for over 2 years and his seizures have nearly disappeared. I don't believe it is a coincidence from switching topical medications, there are many scientific papers out there backing this as well. A great, healthy option and we haven't had any issues with fleas/ticks!