DOUXO S3 CALM Soothing Itchy, Hydrated Skin Dog & Cat Shampoo, 6.7-oz bottle -

Douxo S3 CALM Soothing Itchy, Hydrated Skin Dog & Cat Shampoo

By Douxo S3
Rated 3.8947 out of 5 stars

New Customers Only: Spend 49+ Get $20 off + Free Shipping with code: NEWCHEWY

See Details for instructions to redeem.
$19.99Chewy Price
$21.99Chewy Price
$18.99Autoship Price
Autoship (Save an extra 5%)

Why Autoship?

  • Save 5% on all future Autoship orders
  • Set your schedule based on your pet's needs
  • No fees, no commitments - skip, change or cancel anytime.

In Stock
FREE 1-3 day shipping over $49

About This Item


  • Shampoo for dogs and cats that helps soothe irritated skin.
  • Helps restore the balance of protective microbes.
  • Contains ophytrium, a natural ingredient that helps strengthen the skin barrier.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

See More



Questions & Answers

3 Customer Questions

is the shampoo gentle on the eyes
Answer by ChewyFeb 26, 2022
Avoid contact with eyes. If eye contact occurs, rinse thoroughly and consult your veterinarian. If skin irritation occurs or increases, discontinue use and consult with your veterinarian. Wash hands after using.

What are the ingredients?
Answer by ChewyAug 02, 2021
For a complete list of ingredients you may select the "Ingredients" tab next to the "Description" tab on the product page.

How often can I use this? Is twice a week too often?
Answer by ChewyMar 15, 2023
DOUXO S3 CALM shampoo and mousse are meant to be used together in a clinically proven and consumer-friendly protocol. Use one pump of shampoo for every 4 pounds of body weight. Double the dosage for long and/or thick fur. Wet with cool water from the neck down. First, gently massage shampoo onto the problem area. Repeat on the entire body and leave on for 5-10 minutes before rinsing. Repeat if necessary. Refer to the chart below for usage directions:

ReviewsWrite a Review

Rated 3.8947 out of 5 stars
38 Ratings
Would recommend to a friend

38 Customer Reviews

Rated 5 out of 5 stars
By Dana on Mar 23, 2023

Excellent product

Worked well on my dog she is sensitive to many shampoos. This one worked. My vet game me their product of this brand of foam for my dog she was swollen her skin and itching from other brands the foam helped and also this shampoo. Smells good and made my dog hair soft.

Rated 2 out of 5 stars
By FranksNBeans on Apr 27, 2023

Fragile Spout

When I went to take the tap off the spout, I broke off and its now really hard to pump any soap out.

Rated 3 out of 5 stars
By Gailgirl on Jan 17, 2023

Might be working

My dog has food allergies so my vet recommended this shampoo as well as CADI Immunotherapy shots and a Dermaquin supplement. The scratching stopped within 24 hours of the shot but will probably need to be repeated every 4-6 weeks.

Rated 2 out of 5 stars
By settergal on Sep 30, 2022

new formula?

I have used this product in the past years with good results helping my fur-kids itchy skin. In fact it came recommended by my vet clinic. I didn't see great results shampooing, maybe 1 1/2 days of calm before turning into a flaky mess & itching. i can only assume the ophytrium (which is a new ingredient for me) may have been the trigger. I sadly switched to a different product. I think the original shampoo & emulsifying sprays by douxo were better products.

Rated 5 out of 5 stars
By Maui on Dec 26, 2022

We love it

We've used this shampoo for our English bulldog for about 2 years and it is great for her sensitive skin !

Rated 5 out of 5 stars
By sportzmaster87 on Sep 8, 2022

Great for Allergies!

I love this product!!! My dog has constant itchy and flaky skin so I use this on her every other week and it works great! Her itching is better, her coat is super soft and moisturized, and her flakiness is much better! I love that they added coconut oil to this!!! It adds a wonderful fresh scent and helps soothe her skin. LOVE THIS STUFF. I do wish it wasn't so expensive though.....

Rated 5 out of 5 stars
By Tiff on Sep 26, 2022

Stopped the itching

I love this brand of shampoos for skin issues. Used this on my pup for a few days in a row who was having some skin allergies for a couple weeks due to high pollen count and it stopped the itching and her scratching scabs cleared up.

Rated 5 out of 5 stars
By mebyewin on May 23, 2022

Nice Shampoo

This Shampoo is very nice, although it did require more pumps to use on my little 12 lbs Bichon then recommended. I was hoping this Shampoo would fix her itchy problem, but it hasn't. I believe her skin problem is just allergies. So back to the drawing board.

Rated 5 out of 5 stars
By Rose on Apr 14, 2022

Dog shampoo

This product seems to have worked for her dry skin. My groomer used it on her last visit and she doesn’t seem to have dry flakes at this time. My only negative is my dog is a lab and she’s 97# and this bottle is so small for 25 dollars! I, hoping I can get two visits out of it. With the cost of grooming and then this soap it’s expensive.

Rated 5 out of 5 stars
By Cody on Jun 11, 2022

Dog Shampoo

This works well on our doggie who is very old and has itching problems. The relief doesn't last very long but every little bit helps.