Fluoxetine (Generic) Capsules, 40-mg, 120 capsules

Have a Chewy account?
Sign in to quickly add pet health details.
$16.38 First Time Autoship Price
this order
Save 35% (up to $20) today when you set up Autoship. 

$23.94 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Never miss a dose with easy refills
  • Skip, change, or cancel anytime
$25.20 Chewy Price
($0.21 /ea)
Promo, Save 20% on first Rx order with code RX20
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

In Stock
FREE delivery on first-time orders over $35
Usually arrives in 3-5 days
Prescription approval made easy
We’ll reach out to your vet clinic.

No interest if paid in full in 6 months on PayPal purchases of $149+. .

Medications ship separately. Delivery times may vary.

About This Item

Details

  • Supports calm behavior in dogs and cats: Helps manage dog separation anxiety in conjunction with a behavior modification plan. Other behavioral disorder uses for dogs and cats like aggression are prescribed by your veterinarian.
  • Proven effectiveness: Improvement may be seen in the first week, but may take 4 to 8 weeks or longer to reach full effect to determine if the medication is working.
  • Helps improve quality of life: Pets may feel more relaxed at home or during changes in routine while on this medication.

Ingredients

Instructions

FAQ

Learn More About Fluoxetine From Our Team of Experts

Also available in [tablets] (https://www.chewy.com/dp/173520).

4.8
Rated 4.8 out of 5 stars
2118 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

91% Positive

Effectiveness

90% Positive

Ingredients

89% Positive

Long-Term Benefits

91% Positive

676 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Clare on Jan 28, 2026

Great pricing & medication

I am a veterinarian who often prescribes Fluoxetine for anxiety cases. I constantly send clients to Chewy as it is such a good deal and way cheaper than what my

I am a veterinarian who often prescribes Fluoxetine for anxiety cases. I constantly send clients to Chewy as it is such a good deal and way cheaper than what my clinic sells. I get 20mg for one dog and compounded 26mg for my other via Chewy, and it always arrives very quickly.


Rated 5 out of 5 stars
By Susan on Jan 23, 2026

Chewy has no problem getting the prescriptions approved unlike others

It is nice just to put the order in and not have to worry about, get 15 emails saying "we are trying to contact your vet" and having to make phone calls to get it

It is nice just to put the order in and not have to worry about, get 15 emails saying "we are trying to contact your vet" and having to make phone calls to get it done. Chewy always takes care of it without issue. Thank you


Rated 4 out of 5 stars
By Carol on Nov 28, 2025

It doesn't make much difference

Cuore is still as hyper--and as spiteful--as he's always been. Today, because I'm packing my house to leave on Monday, and he didn't appreciate being gated in the

Cuore is still as hyper--and as spiteful--as he's always been. Today, because I'm packing my house to leave on Monday, and he didn't appreciate being gated in the kitchen, he expressed his displasure by urinating and pooping from one end of the room to the other (when he'd done both, on our morning walk,and it was only two hours later--he's 4 years old, and completely house-trained). I'm at my wits' end, with this dog. I've had a variety of breeds, across my lifetime, and have never seen one with a skull as thick as his is!


Rated 4 out of 5 stars
By Helena on Jan 27, 2026

Takes a while to get in their system

Prozac is an actual antidepressant. It works on animals as well. If your dog does not take a capsule, you can always open the capsule and it into wet. Food works

Prozac is an actual antidepressant. It works on animals as well. If your dog does not take a capsule, you can always open the capsule and it into wet. Food works well once it’s in the dog system.


Rated 5 out of 5 stars
By Linda on Dec 25, 2025

A game changer

Molly has separation anxiety and runs on high speed all day! Since she has been on medication it has been life changing for her( and for her mom and dad,) Thank

Molly has separation anxiety and runs on high speed all day! Since she has been on medication it has been life changing for her( and for her mom and dad,) Thank you Chewy!


Rated 5 out of 5 stars
By Colleen on Nov 30, 2025

Best treatment for pups that are afraid of the world

My Boo developed severe noise and stranger based fear at the age if 3. She was terrified of everything and was self harming, chewing on her foot. Once we went on

My Boo developed severe noise and stranger based fear at the age if 3. She was terrified of everything and was self harming, chewing on her foot. Once we went on this (paired with Gabapentin) she stopped shaking all the time and learned to relax again. She passed away in July but she was given 4 years or calm with the help of this medication. If you have a baby that is scared of the world and shaking, crying all the time ask their vet about this medication to help them.


Rated 5 out of 5 stars
By Renee on Dec 10, 2025

VALUE/EASE OF ORDERING

Using the CHEWY Pharmacy has been a really good choice and I'm extremely happy that we made the change to CHEWY Pharmacy! The convience of getting prescriptions

Using the CHEWY Pharmacy has been a really good choice and I'm extremely happy that we made the change to CHEWY Pharmacy! The convience of getting prescriptions filled and delivered is AMAZING and the price savings is HUGE!


Rated 5 out of 5 stars
By Carole on Dec 3, 2025

Reasonable price

Archer is a recently adopted young Pitbull who is extremely reactive. Both his foster mom and his trainer recommended he be on this calming medication. Chewy had

Archer is a recently adopted young Pitbull who is extremely reactive. Both his foster mom and his trainer recommended he be on this calming medication. Chewy had the best price.


Rated 5 out of 5 stars
By John on Dec 23, 2025

Price was great

It really helped relieve Diesel’s separation anxiety when we have to leave him alone. No digging couch, bed covers or door-jams as he has done in the past.

It really helped relieve Diesel’s separation anxiety when we have to leave him alone. No digging couch, bed covers or door-jams as he has done in the past.


Rated 3 out of 5 stars
By Laura on Nov 22, 2025

Did not work for my reactive pet

My two and a half year old Aussiedor has overwhelmingly reactive behaviors. We tried generic Prozac this spring-summer, and it could not cut the edge off for him

My two and a half year old Aussiedor has overwhelmingly reactive behaviors. We tried generic Prozac this spring-summer, and it could not cut the edge off for him. A stress coat is a big deal for my Booker dog.