Proin Chewable Tablets for Dogs

Prescription Item

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In stock
Strength: 50-mg
  • 25-mg In stock
  • 50-mg In stock
  • 75-mg In stock
Count: 1 tablet
  • 1 tablet In stock

This item requires prescription approval. Details

Medications ship separately. Delivery times may vary. Details

This item cannot be shipped to AR, IA, LA, OR, WV, or MS.

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Proin is a chewable tablet prescribed by your veterinarian to treat and manage urinary incontinence in dogs. It works by helping to tighten the bladder and urethral muscles to prevent urine leaking and accidents. Best of all, it comes in a tablet, so you can feed it to your pet by mouth or disguise it inside a tasty pill pocket.


For the control of urinary incontinence due to urethral sphincter hypotonus in dogs.

Possible Side Effects

Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting this medication.


Proin may cause increased thirst. Provide ample fresh water.

  1. Prescribing Information

See all items by Proin

  • Item Number
  • Common Brand Name(s)


  • Generic Name

    Phenylpropanolamine Hydrochloride

  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Restricted Availability

    AR, IA, LA, OR, WV, MS

  • For Use With


  • Brand

    PRN Pharmacal

  • Product Form

    Chewable Tablet

  • Health Condition


  • Drug Type

    Adrenergic Agent


Active Ingredients: Phenylpropanolamine Hydrochloride.

Inactive Ingredients: Stearic Acid, Soy Protein, Silicon Dioxide, Whey, Garlic, Chicken Liver.

Recommended Dosage

The total recommended dosage for oral administration is 2 mg/kg (0.91 mg/lb) of body weight twice daily. Proin is scored and dosage should be calculated in half-tablet increments.

Storage Instructions

Store at controlled room temperatures 68° - 77°F.


Why Proin?

  • Only FDA approved PPA for the treatment of urinary incontinence due to urethral sphincter hypotonus with proven efficacy.
  • Offers three tablet strengths of half scored, liver-flavored tablets allowing health care providers to tailor the dosage for most dogs.
  • Formulated as a liver-flavored tablet to help make dosing easier.

What are the common clinical signs of urinary incontinence in dogs?

  • Dripping or leaking urine.
  • Excessive licking of the genital area.
  • Red and irritated skin around the genital area.
  • Needing to go more frequently than normal.
  • Wetting the bed or sleeping area.
  • Urinating inappropriately in the house.

Fortunately, while frustrating at first, canine urinary incontinence may be controlled with Proin, a safe and effective FDA-approved chewable tablet that works by increasing urethral sphincter tone to help prevent urinary accidents.

Customer Reviews
2 Reviews 2 Reviews 4.5 out of 5 Stars

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  • It Works!!!

    By on

    We have an almost 1 year old chessie and she can't control her bladder. We've had multiple tests with no real results and finally started with Proin. She now has stopped having accidents in the house except for the very exciting moments like a stranger coming to visit. It's been very helpful. And half the price of the vets office.

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  • Happier Beagle

    By on

    Around the age of 12, my beagle began to have accidents. He would pee while he was walking, seeming to not realize he was doing it at all. Two weeks of Proin, twice a day, and my boy's bladder strength had returned. I'm happy to see that I can have it shipped to my home because my work hours make it difficult to get to the vet for refills and I pay about half the price through Chewy. I just wish Chewy would make it available for auto- ship so I could add it to the food shipments I've already scheduled.

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