Sentinel Spectrum Chew for Dogs, 2-8 lbs, (Orange Box)
By Sentinel Spectrum

- In Stock
- In Stock
Shipping for Prescription Medications
Our pharmacy prepares and ships prescription medications separately to ensure proper handling.
Most prescriptions are delivered within 3-5 days.Frequently Bought Together
About This Item
Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Sentinel Spectrum is a monthly oral preventive prescription that protects your pet against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. Best of all, this medication may also help protect your pal against heartworm disease and intestinal worms, all in a tasty, flavored chewable tablet.
Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.
Specifications
Item Number | 146440 |
---|---|
Common Brand Name(s) | Sentinel |
Generic Name | Milbemycin Oxime, Lufenuron, Praziquantel |
For Use With | Dogs |
Administration Form | Oral |
Breed Size | Extra Small & Toy Breeds |
Product Form | Chew |
Strength | 2.3 mg Milbemycin Oxime, 46 mg Lufenuron and 22.8 mg Praziquantel |
Health Condition | Heartworms, Hookworms, Roundworms, Whipworms, Tapeworms, Fleas |
Drug Type | Parasiticide |
Uses
Sentinel Spectrum is indicated for the prevention of heartworm disease. It is also formulated to help prevent and control flea populations, and for the treatment and control of adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies six weeks of age and older and weighing at least two pounds.
Possible Side Effects
The following adverse reactions have been reported in dogs after administration of milbemycin oxime, lufenuron, or praziquantel: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, salivation, and weakness.
Drug & Food Interactions
There are no known contraindications to the use of Sentinel Spectrum.
Precautions
Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Sentinel Spectrum, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. This medication is not effective against adult D. immitis. Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Do not use in puppies less than six weeks of age. Do not use in dogs or puppies less than two pounds of body weight. The safety of this medication has not been evaluated in dogs used for breeding or in lactating females. Studies have been performed with milbemycin oxime and lufenuron alone. Not for use in humans. Keep this and all drugs out of the reach of children.
Ingredients
2.3 mg Milbemycin Oxime, 46 mg Lufenuron and 22.8 mg Praziquantel.
Recommended Dosage
Sentinel Spectrum should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, 4.55 mg/lb (10 mg/kg) lufenuron, and 2.28 mg/lb (5 mg/kg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes.
The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the doses have been lost, redosing is recommended.
Heartworm Prevention: Sentinel Spectrum should be administered at monthly intervals beginning within 1 month of the dog’s first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog’s last seasonal exposure. Sentinel Spectrum may be administered year-round without interruption. When switching from another heartworm preventative product to Sentinel Spectrum, the first dose of Sentinel Spectrum should be given within a month of the last dose of the former product.
Flea Treatment & Prevention: Treatment with Sentinel Spectrum may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with Sentinel Spectrum should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product, as necessary.
Intestinal Nematode & Cestode treatment and control: Dogs may be exposed to and can become infected with roundworms, whipworms, hookworms, and tapeworms throughout the year, regardless of season or climate. Clients should be advised of appropriate measures to prevent reinfection of their dog with intestinal parasites. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.
Storage Instructions
Store in a dry place at controlled room temperature between 59° - 77°F.
How are Sentinel Spectrum and Sentinel Flavor Tabs different from other heartworm medications?
Not all heartworm medicines provide the same spectrum of parasite protection. Sentinel Flavor Tabs are chewable tablets that protect dogs against fleas, heartworms, roundworms, hookworms, and whipworms. Sentinel Spectrum is a soft, beef and bacon flavored chew that adds tapeworm protection to offer the broadest coverage available.
My dog weighs more than 100 pounds. Are Sentinel Specturm or Sentinel Flavor Tabs a good option for him?
Yes. Talk to your veterinarian about the appropriate dose for your pet.
My dog is a toy breed. Are Sentinel Specturm or Sentinel Flavor Tabs okay for his small size?
Yes. Both Sentinel Specturm and Sentinel Flavor Tabs offer a size that can be given to small dogs. Sentinel Spectrum has a size available for dogs weighing from 2–8 lbs and Sentinel Flavor Tabs has a size available for dogs weighing from 2–10 lbs.
I see a few fleas on my dog. Is the medication working?
You may see an occasional “hitchhiker” adult flea that your dog has picked up at the dog park or in the yard or other infested environments where 95% of the flea population lives in the form of eggs, maggot-like larvae, and pupae. Sentinel Specturm and Sentinel Flavor Tabs put an end to fleas before they become adults. You may need an adulticide, such as Effitix Topical Solution for Dogs, to treat occasional adult fleas.
Can I give either Sentinel Spectrum or Sentinel Flavor Tabs to my cat?
No, both Sentinel Spectrum and Sentinel Flavor Tabs are only approved for use in dogs.

Dosage Chart
Color on Box | Weight Range | Strength | Dosage | Product Page |
---|---|---|---|---|
Orange | 2-8 lbs | 2.3 mg Milbemycin Oxime, 46 mg Lufenuron & 22.8 mg Praziquantel | Administer orally once a month | ✓-Click Here |
Green | 8.1-25 lbs | 5.75 mg Milbemycin Oxime, 115 mg Lufenuron & 57 mg Praziquantel | Administer orally once a month | ✓-Click Here |
Yellow | 25.1-50 lbs | 11.5 mg Milbemycin Oxime, 230 mg Lufenuron & 114 mg Praziquantel | Administer orally once a month | ✓-Click Here |
Blue | 50.1-100 lbs | 23 mg Milbemycin Oxime, 460 mg Lufenuron & 228 mg Praziquantel | Administer orally once a month | ✓-Click Here |
Pet Lovers Also Bought
- Sentinel Spectrum Chew for Dogs, 8.1-25 lbs, (Green Box), 6 Chews (6-mos. supply)Rated 4.5905 out of 5 stars105$52.99Chewy PriceChoose OptionsAdded to Cart
- Sentinel Spectrum Chew for Dogs, 50.1-100 lbs, (Blue Box), 6 Chews (6-mos. supply)Rated 4.177 out of 5 stars113$77.49Chewy PriceChoose OptionsAdded to Cart
- Bravecto Chew for Dogs, 4.4-9.9 lbs, (Yellow Box), 1 Chew (12-wks. supply)Rated 4.7087 out of 5 stars103$59.99Chewy PriceChoose OptionsAdded to Cart
- NexGard Chew for Dogs, 4-10 lbs, (Orange Box), 3 Chews (3-mos. supply)Rated 4.6713 out of 5 stars216$68.99Chewy Price$65.54Autoship PriceAutoshipChoose OptionsAdded to Cart
- Sentinel Spectrum Chew for Dogs, 25.1-50 lbs, (Yellow Box), 6 Chews (6-mos. supply)Rated 4.625 out of 5 stars56$64.49Chewy PriceChoose OptionsAdded to Cart
- Simparica Chewable Tablet for Dogs, 5.6-11 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply)Rated 4.6944 out of 5 stars72$97.73Chewy Price$92.84Autoship PriceAutoshipChoose OptionsAdded to Cart
- Bravecto Chew for Dogs, 9.9-22 lbs, (Orange Box), 1 Chew (12-wks. supply)Rated 4.7252 out of 5 stars353$61.99Chewy PriceChoose OptionsAdded to Cart
- NexGard Chew for Dogs, 60.1-121 lbs, (Red Box), 6 Chews (6-mos. supply)Rated 4.7114 out of 5 stars790$125.99Chewy Price$119.69Autoship PriceAutoship
Bundle Heartgard Plus with NexGard and Save 15% Off at Checkout With Code: HGNG15
Choose OptionsAdded to Cart - Apoquel Tablets for Dogs, 3.6-mg, 1 tabletRated 4.6913 out of 5 stars2,057$2.53Chewy Price$2.40Autoship PriceAutoship
Save 50% on First Autoship With Code: HEALTH50
Choose OptionsAdded to Cart - Sentinel Tablet for Dogs, 2-10 lbs, (Brown Box), 6 Tablets (6-mos. supply)Rated 4.7879 out of 5 stars66$47.99Chewy Price$49.00List PriceChoose OptionsAdded to Cart
ReviewsWrite a Review
27 Customer Reviews
Very Pleased
Our Fur Son ITTY-BITTY only 6 lb (A MORKIE) we started him on Sentinel at his second vet appointment he's been on it ever since and he will be 1 on the 27th of this month I think Sentinel is awesome it works extremely well although he doesn't go outside at all unless he's unless it's appointments and when he does he's constantly his stroller therefore he doesn't be around dogs so I don't have to worry about the flea part but this does work apparently well against fleas as well he does not like it by itself so we literally always have to crush it up in little pieces to camouflage it with his wet food what they said I definitely recommend this product this will be my second 6 month supply
So easy to use!
This product is so easy to use and works very well. Much better than the topical flea medicine. My 3lb. Yorkie gobbles them up each month without having to "hid" it in cheese!
One of the better ones
Great for small dogs that mostly stay at home. A bit hard for them to chew. Not a great flavor!!
As expected
Was a little worried about ordering his medication online that it might be close to expiration date or expired. But dates were fine abc it was genuine product.
Excellent Service
Chewy takes responsibility to obtain Rx from the vet and then ships. Great service especially when your vet is not relatively close. Keeps you informed of the status of your order. Great customer service.
Good product
I think Sentinel is a good product at a good price
Thanks for great product
Great product and was shipped immediately and received within a few days
Great product
Was recommended by my dog’s Vet Been easy to be eaten by my Pixie
Convenient!
We have used Sentinel Spectrum for 4 years now for my Pomeranians and Frenchie. Very convenient and I haven't noticed any side effects. The only down side is the price has jumped up almost double but still worth the price. I love Chewy they are so helpful when filling my dogs Rx
Husbands a chemist and looked into all sides effects before buying this.
Just started using it and no side effects for out small girls. We used bravecto as directed by our Vet and the puppies weren’t looking good for a few days and had diarrhea also one had some aggression. It looks like it’s calming the demodex eye mites one has. We tried bravecto and they’ve come back again. So hopefully keeping up with this will do the trick.