Simparica Chewable Tablet for Dogs, 2.8-5.5 lbs, (Yellow Box)
Prescription Item
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Say goodbye to pesky, persistent pests and hello to Simparica. This once-a-month tablet gives you an easy, reliable way to protect your dog from fleas and ticks. It's a tasty tablet that works to shield your pet for a full 35 days, killing fleas before they can lay eggs. It helps to prevent home infestations and tick-borne illnesses. Plus, unlike other medications, Simparica doesn't need to be given with food. Simply feed him one chewable tablet, just like a monthly treat, and give your companion the broad-spectrum protection he deserves.
UsesSimparica kills adult fleas, and is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations from lone star ticks, Gulf Coast ticks, American dog tick, black-legged ticks and brown dog ticks for one month in dogs 6 months of age or older and weighing at least 2.8 lbs.
Possible Side EffectsSide effects that usually are not serious include:
- Vomiting, diarrhea.
- Low energy level.
If any of these signs are severe, worsen, or continue to be a problem, contact your veterinarian.
Side effects that may be serious or indicate a serious problem:
- Vomiting or diarrhea that does not stop.
- Tremors, seizures.
- Difficulty walking (eg, weakness, stumbling).
If you see any of these signs, contact your veterinarian immediately.
Drug & Food InteractionsThere are no known contraindications to the use of Simparica.
Precautions
Simparica is for use only in dogs, 6 months of age and older. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. Simparica has been safely used in dogs treated with commonly prescribed vaccines, parasiticides and other medications. The most frequently reported adverse reactions were vomiting and diarrhea. See full Prescribing Information.
Dosage Chart
Color on Box | Weight Range | Strength | Dosage | Product Page |
---|---|---|---|---|
Yellow | 2.8-5.5 lbs | 5 mg Sarolaner | Administer orally once a month | ✓-Click Here |
Purple | 5.6-11.0 lbs | 10 mg Sarolaner | Administer orally once a month | ✓-Click Here |
Orange | 11.1-22.0 lbs | 20 mg Sarolaner | Administer orally once a month | ✓-Click Here |
Mint | 22.1-44.0 lbs | 40 mg Sarolaner | Administer orally once a month | ✓-Click Here |
Green | 44.1-88.0 lbs | 80 mg Sarolaner | Administer orally once a month | ✓-Click Here |
Brown | 88.1-132.0 lbs | 120 mg Sarolaner | Administer orally once a month | ✓-Click Here |
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Item Number146274
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Common Brand Name(s)Simparica
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Generic NameSarolaner
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For Use WithDogs
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Administration FormOral
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UsagePrevention, Treatment
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BrandZoetis
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Breed SizeExtra Small & Toy Breeds
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Product FormChewable Tablet
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Strength5 mg Sarolaner
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Health ConditionFleas, Ticks
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Drug TypeParasiticide
5 mg Sarolaner, Hydrolyzed Soy Protein, Starch, Corn, Wheat Germ, Anhydrous Dibasic Calcium Phosphate, Corn Syrup, Gelatin.
Simparica is given orally once a month at the recommended minimum dosage of 0.91 mg/lb (2 mg/kg).
Simparica can be offered by hand, in the food, or administered like other tablet medications. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If a dose is missed, administer Simparica and resume a monthly dosing schedule. Simparica should be administered at monthly intervals.
Flea Treatment and Prevention: Treatment with Simparica may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with Simparica can continue the entire year without interruption. To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with an approved flea control product.
Tick Treatment and Control: Treatment with Simparica can begin at any time of the year.
Storage InstructionsStore at or below 86°F.
How Does Simparica Work?
Simparica is a great tasting chewable tablet given orally once a month. It travels in your dog's blood to safely deliver persistent continuous protection against fleas and ticks from day 1 to day 35.
Why protect against fleas and ticks?
Tick-borne diseases represent a widespread and growing public health hazard to dogs (and their human companions), causing debilitating illness and even death. It only takes one tick to spread disease, so continuous protection is critical to help reduce the risk of infection.
Likewise, it only takes a single "pregnant" flea to start an infestation on a dog or in a home. And although fleas are largely perceived as a mere nuisance, they too, can pose health risks to pets and humans.
Customer Reviews

90% Recommend
90% of reviewersrecommend this product
You've Already Reviewed This Item
10 Reviews
10 Reviews
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Just what I needed!
By OPPetlvr on Aug 30, 2020
This is one of the very few products that covers small dogs. This flea and tick treatment is a year round must for our midwest weather! Thankfully Chewy had it! They sent it rapidly, new and in original package!
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SIMPARICA KEEPS MY KIDZ HAPPY & FLEA FREE!!! ;-)
By Dolly on Jul 25, 2020
1 of my kids was allergic 2 a different flea med, so I tried Simparica & i was satisfied with it's results. It keeps the fleas away & my kidz happy ;-). If ur not satisfied with ur current flea med, give Simparica a try.
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Works Great!!!
By Charycebon on Mar 6, 2020
My dog is 13 yrs old and we never had a huge issue with fleas where I lived. There were periods of time when he would go to SC and would be infested with them. All the baths didn't help so I was recommended by his vet to use Comfortis. That was amazing and we didn't have anymore issues until recently. I'm in another state now and I took him to a dog sitter who had him almost two weeks (I was out of the country and couldn't bring him with me). She had several dogs she was sitting at the time including 3 of her own. She told me she gave him a bath, but when I got home that's when I noticed the fleas. I tried to order Comfortis but unfortunately it was declined by my vet because it wasn't in his My dog is 13 yrs old and we never had a huge issue with fleas where I lived. There were periods of time when he would go to SC and would be infested with them. All the baths didn't help so I was recommended by his vet to use Comfortis. That was amazing and we didn't have anymore issues until recently. I'm in another state now and I took him to a dog sitter who had him almost two weeks (I was out of the country and couldn't bring him with me). She had several dogs she was sitting at the time including 3 of her own. She told me she gave him a bath, but when I got home that's when I noticed the fleas. I tried to order Comfortis but unfortunately it was declined by my vet because it wasn't in his weight class. My dog is 2.8 lbs and the lowest dosage they have was 3.3 lbs. They recommended Simparica in its place and I haven't had anymore issues with fleas! … more
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Happy dogs
By Joker on Mar 31, 2020
My vet recommended this product and I really like it. My dogs do well with it and it is easy to hide in their food. They are finicky treat takers so being able to put it in their food has been so easy with this pill. We travel and I love the flea and tick protection with Simparica.
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WORKS GREAT! THE BEST!!
By B3ST on Apr 22, 2020
I been giving my dog Simparica for almost 3 years now and I can not complain. Gets the job done and my dog has not had any problems with fleas! I would highly recommend if your looking for a great flea pill!
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Flea and Tick Medicine
By HappyPets on Dec 4, 2019
Thank you for providing this medicine. Our vet did not carry the small dog dose and we were in need. Your company acquired the prescription and delivered the medicine quickly. We appreciate your quick service and quality products.
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Gets the jobs done
By Disneypup on Aug 3, 2019
Our apartment complex is loaded with flees due to the stray cats. My poor Athena and Sparta were covered in fleas. We could not get them to go away no matter how many flea baths and combs we ran them through. We went to the vet and they were both put on the Simparica. We have not seen 1 flea on either them and it has been 3 months.
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Great for small dog
By Hondo on Oct 23, 2019
I like this product because it is very small for my 5 pound Morkie to eat. The flavor must be good too because she is a picky eater and she ate this right up.
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Worked like a charm!
By Yorkiemom on Feb 26, 2019
Worked immediately! Fleas gone! Dogs and mom are both happy! Will purchase again.
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Flea medicine
By Boston on Oct 18, 2018
Still itching n biting due to fleas not having good luck so far with product