Simparica Chewable Tablet for Dogs, 2.8-5.5 lbs, (Yellow Box), 6 Chewable Tablets (6-mos. supply)

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$117.32 Autoship Price
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$123.49 Chewy Price
($20.59 /ea)
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Usually arrives in 3-5 days
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About This Item

Details

  • 35-Day Flea and Tick Prevention for Dogs: Simparica is a tasty, once-a-month chewable that protects your dog from fleas and ticks for 35 days, even if the next dose is a few days late.
  • Kills 6 Types of Ticks: Proven to kill Gulf Coast, Brown Dog, Deer, American Dog, Lone Star, and Asian Longhorned ticks.
  • Helps Prevent Lyme Infections: FDA-approved to block infections that may cause Lyme disease by killing deer ticks.
  • Fast-Acting Relief: Starts killing fleas within 3 hours and ticks within 8 hours. Kills adult fleas before they lay eggs to help stop infestations fast.
  • Tasty, Once-a-Month Chewable: Pork-liver flavored for easy dosing. Approved for dogs 6 months and older weighing at least 2.8 lbs, and backed by a 100% satisfaction guarantee on prevention.

Ingredients

Instructions

FAQ

Learn More About Simparica From Our Team of Experts

Protects Dogs From Ticks & Fleas for 35 days

Simparica is tasty pork liver-flavored, veterinarian-recommended monthly chew that protects your dog from fleas and ticks for a full 35 days.[1] It works fast and starts to kill fleas in 3 hours and ticks in 8 hours.[2] Simparica is approved for dogs 6+ months of age, weighing 2.8 lbs or more.

FDA-Approved to Prevent Lyme Infections*

Because it kills deer ticks, Simparica is FDA-approved to block infections that may cause Lyme disease. It kills 6 different types of ticks, including:

  • Gulf Coast Tick
  • Deer Tick
  • American Dog Tick
  • Lone Star Tick
  • Brown Dog Tick
  • Asian Longhorned Tick

Satisfaction Guaranteed

Simparica comes with a 100% satisfaction guarantee on prevention—so you can feel confident choosing fast, reliable protection. It’s a simple way to stay proactive about your dog’s care, with support you can count on.

Protect Your Dog & Earn Rewards From Zoetis

Your 6-or 12-count Simparica purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Rimadyl

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

Simparica is for use only in dogs 6 months of age and older. Simparica, which contains sarolaner, a member of the isoxazoline class, may cause neurologic signs such as tremors, unsteadiness, and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding, or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information at SimparicaPI.com.

*Data on file, Zoetis Services LLC.

References:Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Comparative speed of kill of sarolaner (Simparica®) and afoxolaner (NexGard®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:90Honsberger NA, Six RH, Heinz TJ, et al. Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs. Vet Parasitol. 2016;222:67–72 (AR-04287).

SMP-00748

4.7
Rated 4.7 out of 5 stars
154 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

89% Positive

Effectiveness

84% Positive

Ingredients

82% Positive

Long-Term Benefits

85% Positive

51 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 4 out of 5 stars
By John on Nov 3, 2025

Customer Service Was Exceptional

Helped getting order approved, quick shipment and help finding were the delivery was made. This was the 1st time I ordered a prescription for my dog from Chewy

Helped getting order approved, quick shipment and help finding were the delivery was made. This was the 1st time I ordered a prescription for my dog from Chewy. The next time I do, I expect the process to be much better! Based on support from Customer Service, I would recommend Chewy to others.


Rated 5 out of 5 stars
By Lashaunda on Nov 4, 2025

Small

It was easy to give her she ate it quickly and within days she was totally healed from fleas and ticks! I had tried all the over the counter medication including

It was easy to give her she ate it quickly and within days she was totally healed from fleas and ticks! I had tried all the over the counter medication including top notch over the counter medications none of them worked but this simparica worked the first time!


Rated 5 out of 5 stars
By Michael on Oct 11, 2025

this is the stuff!!

our little Rosie cant use topicals, they leave blisters on her skin, but this stuff works great!!!

our little Rosie cant use topicals, they leave blisters on her skin, but this stuff works great!!!


Rated 5 out of 5 stars
By Betty on Nov 23, 2025

Best flee and tick meds for dogs

This is the only brand we use for our dogs! Would recommend it!!!

This is the only brand we use for our dogs! Would recommend it!!!


Rated 5 out of 5 stars
By Azucena on Sep 22, 2025

Always on time and easy to order

This is the flea treatment my vet has recommended and it's definitely better priced via Chewy

This is the flea treatment my vet has recommended and it's definitely better priced via Chewy


Rated 5 out of 5 stars
By Shelley on Jul 7, 2025

Great product

I always use this product for my little dog and works well. She likes to chew it. I could not get the product from the vet anymore and Chewy carries it. Easy

I always use this product for my little dog and works well. She likes to chew it. I could not get the product from the vet anymore and Chewy carries it. Easy to order and comes very quickly


Rated 5 out of 5 stars
By Maria on Jun 25, 2025

In glad Chewy simplified filling RXs

I like that Chewy now can contact your vet to confirm the Rx. Having to mail in a script was inconvenient which is why I never used their pharmacy. But if they now

I like that Chewy now can contact your vet to confirm the Rx. Having to mail in a script was inconvenient which is why I never used their pharmacy. But if they now contact my vet, I’ll happily buy my pet meds from them.


Rated 4 out of 5 stars
By Cheryl on Oct 21, 2025

Price & the auto send

These are Vet recommended. I don't worry about my girls

These are Vet recommended. I don't worry about my girls


Rated 5 out of 5 stars
By Doris on May 19, 2025

The box

I love that I can get this delivered to my door and Chewy has what I need. He is so little that my vet didn’t carry it there.

I love that I can get this delivered to my door and Chewy has what I need. He is so little that my vet didn’t carry it there.


Rated 5 out of 5 stars
By judy on Jan 14, 2026

Prompt delivery

Prompt delivery

Prompt delivery