Zymox Topical Dog & Cat Enzymatic Skin Cream, 1-oz tube

By Zymox
Rated 4.3125 out of 5 stars
$11.79 (-26%)Chewy Price
$15.99Chewy Price

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About This Item


  • Provides gentle, soothing relief from skin irritations like itchy skin, hot spots, dermatitis and more.
  • Soothing ointment helps manage painful skin issues without using harsh chemicals or alcohol.
  • No pre-cleaning is required, making applications less painful.
  • Paw-fect for dogs and cats of all ages, ZYMOX Topical Cream is made with gentle ingredients that are safe if licked after application.
  • Veterinarian-strength pet formula is ideal for skin irritations to the face, paws and body folds.

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Play Video: Learn More About Zymox From Our Team of Experts
Learn More About Zymox From Our Team of Experts

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This Item – Zymox Topical Dog & Cat Enzymatic Skin Cream, 1-oz tube
Rated 4.3125 out of 5 stars
$11.79Chewy Price

Buy 2, Get 3rd Free- Mix & Match

Total Price: $39.43

About ZYMOX Enzymes for Healthy Ears and Skin

Antimicrobial and Antifungal Care

ZYMOX empowers pet parents with patented formulations of natural enzymes to help treat chronic infections in dogs, cats and horses. Their products are formulated to be safe to use on any age pet. ZYMOX packs a potent antimicrobial punch that targets the source of infections—bacteria and fungus(including yeast) to provide therapeutic relief, care, protection and prevention, without any antibiotics or harsh chemicals. Proudly made in the USA and endorsed by TICA (The International Cat Association).

Committed to Healthy Ears, Skin and Coat, and Smiles

To ensure overall health from snout to tail on all four-legged pals, Zymox has developed products that are specially formulated for all the areas that commonly need infection relief, like the ears, teeth and gums, and skin and coat.

Ear Care Solutions

Effective, non-toxic solutions with special enzymes and mild cleansers to keep ears clean and fresh, and combat microbes that can cause ear infections.

Oral Care Solutions

Brushless solutions with unique enzymes to dissolve plaque and prevent its buildup, boost natural "good bacteria," and protect against gum disease to keep kitty and doggy smiles healthy.

Skin and Coat Health

Topical sprays and shampoos for dogs, cats and horses that form a powerful protective barrier against minor skin inflammations from bacteria and fungi, while cleaning and conditioning the coat—with some formulas utilizing hydrocortisone.

100% Safe, Gentle and Easy

Because Zymox formulas are made with 100% naturally derived enzymes from dairy, they are safe for anytime use, both for immediate soothing relief and to prevent infections. The powerful enzymes work to eliminate problem single-celled organisms such as bacteria, fungi and yeast, while leaving healthy cells untouched. This means no irritations for your pal!

Enzyme-Based and Antibiotic-Free

Zymox products use a patented, gentle formulation that combines three potent, naturally occurring enzymes—lactoperoxidase, lysozyme and lactoferrin—that are sourced from milk products. These enzymes are proven to work together to eliminate the source of infection on your pet, without any toxins or antibiotics that can irritate or cause antibiotic resistance.


Zymox was founded in 1998 by Pamela Bosco, who sought to change the way that people treated and managed ear, oral and skin infections with a safer alternative to antibiotics. Enlisting the help of her brother—a scientist that developed the enzyme technology in Biotene—Bosco formulated a powerful enzyme-based solution to help treat infections in dogs, cats and horses with no toxins, chemicals or antibiotics. Committed to keeping all four-legged pals healthy, they offer USA-made and sourced products to treat, soothe and protect against bacterial and fungal infections gently and 100% naturally.

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Top IngredientsAloe Vera, Benzyl Alcohol, Dextrose...Purified Water, Nano-Enhanced Minerals, Witch Hazel Extract...Shea Butter, Almond Oil, Coconut Oil...
Health FeatureSkin & Coat HealthSkin & Coat HealthSkin & Coat HealthEar CareSkin & Coat Health
Breed SizeSmall Breeds, Medium Breeds, Large Breeds

Questions & Answers

16 Customer Questions

Can this be used in or on cats ears?
Answer by ChewyJul 01, 2021
It is recommended to avoid contact with eyes or mucous membranes. Do not apply to large areas of the body. We recommend speaking to your vet to see if this would be suitable for your pet's current treatment plan.

Can this be used in a dogs ears for yeast infection?
Answer by ChewyDec 22, 2017
The Enzymatic Skin Cream isn't recommended to use in the ears, you would want to use the Zymox Otic.

can it be used on warts
Answer by ChewyApr 16, 2022
This cream can help relieve red, inflamed skin and is effective against bacteria, fungus and yeast.

is there an cortisone or steriods in this
Answer by ChewyJul 31, 2021
This cream is hydrocortisone-free and is recommended for those animals sensitive to corticosteroids. For a complete list of ingredients, click the “Ingredients” tab on the product page.

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Rated 4.3125 out of 5 stars