Zymox Enzymatic Topical Spray with Hydrocortisone 0.5% for Dogs & Cats, 2-oz bottle

By Zymox
Rated 4.6957 out of 5 stars
Slide 1 of 8
Zymox Enzymatic Topical Spray with Hydrocortisone 0.5% for Dogs & Cats, 2-oz bottle slide 1 of 8
Slide 1 of 8
Zymox Enzymatic Topical Spray with Hydrocortisone 0.5% for Dogs & Cats, 2-oz bottle slide 1 of 8
$13.99Chewy Price
$17.99Chewy Price
$13.29Autoship Price
Autoship (Save an extra 5%)
Choose Autoship at checkout for regular deliveries.

Why Autoship?

  • FREE access to chat with licensed vets 7 days a week.
  • Save 5% on all future Autoship orders.
  • No fees, no commitments - cancel Autoship anytime.

In Stock
FREE 1-3 day shipping over $49

Frequently Bought Together

Frequently Bought Together
Rated 4.6957 out of 5 stars
$13.99Chewy Price
Frequently Bought Together
Rated 4.6423 out of 5 stars
$14.99Chewy Price
Frequently Bought Together
Rated 4.8577 out of 5 stars
$22.49Chewy Price
Total Price: $0.00

About This Item

  • Gentle, enzymatic approach to first aid care for wounds, cuts, hot spots and even mild skin infections. It's so gentle, it's even suitable for kittens and puppies!
  • Contains hydrocortisone for inflammation and itch relief.
  • No pre-cleaning or scrubbing of the area before use.
  • LP3 Enzyme System reacts with the infectious pus and debris to form its antimicrobial properties.
  • Made in the USA.
Play Video: Learn More About Zymox From Our Team of Experts
Learn More About Zymox From Our Team of Experts

Compare Similar Items

Customer Rating
Rated 4.6957 out of 5 stars
Rated 4.3636 out of 5 stars
Rated 3 out of 5 stars
Rated 4.25 out of 5 stars
Rated 4.5759 out of 5 stars
$13.99Chewy Price
$12.99Chewy Price
$17.99Chewy Price
$12.00Chewy Price
$14.99Chewy Price
$13.29Chewy Price
$12.34Chewy Price
$17.09Chewy Price
$11.40Chewy Price
$14.24Chewy Price
Top IngredientsHydrocortisone 0.5%, Aloe Vera, Benzoic Acid...Glycerin, Purified Water, Propylene Glycol...Active: Hydrocortisone 1%, Pramoxine Hydrochloride 0.5%, Inactive: Propylene Glycol...Colloidal Silver, Boric Acid, Witch Hazel...Active Ingredients: Hydrocortisone 1.0%., Inactive Ingredients: Aloe Vera, Benzoic Acid...
Breed SizeN/AN/ASmall Breeds, Medium Breeds, Large BreedsSmall Breeds, Medium Breeds, Large BreedsN/A
Health FeatureSkin & Coat Health, Itch & Redness RemedySkin & Coat HealthAllergy ReliefN/AItch & Redness Remedy, Skin & Coat Health

Questions & Answers

6 Customer Questions

can this product be used for ear infections on my dog?
Answer by ChewyJun 16, 2018
This product is formulated for wounds, cuts, hot spots and even mild skin infections, however, it is not recommended to be used for ear infections.

Will this make my cat sick if they lick the affected area after applying this product?
Answer by ChewyAug 11, 2018
While licking this spray wont cause sickness, you should prevent the pet from licking to allow it to dry.

Is this safe to use on a female dogs private areas?
Answer by ChewyDec 12, 2019
We recommend testing a small area to ensure your pet doesn't have an adverse reaction. This spray does contain alcohol, the Zymox Enzymatic Topical Cream with Hydrocortisone 0.5% for Dogs & Cats may be more suitable.

Can this be used long term on a cat with environmental allergies?
Answer by ChewyMay 13, 2020
It is recommended to use topical spray once daily up to 7 days. If condition persists or worsens for more than 7 days, stop use and consult a veterinarian.

ReviewsWrite a Review

Rated 4.6957 out of 5 stars
46 Reviews
Would recommend to a friend

46 Customer Reviews

Rated 3 out of 5 stars
By Bellamax on Oct 8, 2021

Turns white fur yellow! Unsure if it works.

After using this as directed a couple of times on my small terrier mix, I noticed her fur turned yellow where applied. I am not sure if it is actually working but will monitor a hot spot closely.

Rated 1 out of 5 stars
By GoodKarmaCats on Aug 14, 2021

Wish I knew how the actual product works.

Unfortunately, this product arrived in a plastic bag which is virtually unopenable due to having leaked during transit. While I appreciate that it was put in a plastic bag, the sensible thing to do would be to tighten the lid to minimise the likelihood that it would leak. I rescue cats who often have itchy, raw spots from flea bites and I was really hopeful this product would work for them.

Rated 5 out of 5 stars
By Pixie on Jun 2, 2021

WOW! What a great product!

My furbaby, Taffie, Has been on medication for her skin issues for several years now. I stopped using the medication and ordered this product. I am amazed - after using for a few days, the issues have all but gone away - her skin is healthier than it's been in a long time. Awesome product!

Rated 5 out of 5 stars
By Cindy on Mar 29, 2021

This product actually worked!

My miniature schnauzer seems to suffer from a troublesome spot on her neck every time I get her groomed. She starts scratching that one particular spot causing it to bleed sometimes. I tried another product in the past, but it did not work. After reading the reviews for Zymox I thought I'd give it a try. Within a day, she didn't scratch as much; and after about two days, the Zymox definitely was effective in helping eliminate the problem.

Rated 5 out of 5 stars
By LizC on Mar 4, 2021

Live this product!

I definitely recommend this product! My cat's scratching this winter was getting so bad his while back was scabbed up and he was miserable! The mixture of this and putting salmon oil in his food has his whole back cleared up in a week!!!

Rated 5 out of 5 stars
By Yummy on Mar 29, 2021

Good Stuff

Good Stuff. You will not be disappointed - see an improvement in about 4 days. Good stuff. it does have a steroid in it, so make sure applying to the correct type of need

Rated 5 out of 5 stars
By DeeDee on Mar 4, 2021

ear spray for dogs

This works great on my basset's ears. When he starts shaking his head a lot we spray this in his ears. It helps him immediately.

Rated 5 out of 5 stars
By Chelle on Mar 27, 2021

Itchy paws dog

Excellent for tuckers paw. Was red and irritated. Healed quickly

Rated 5 out of 5 stars
By Zymox on Aug 28, 2020

Zymox is really great stuff !

The underside of our rat terrier had been itchy and red for a long time. She would scratch it a lot and it never seemed to get better. We used regular hydrocortisone cream and that helped some, but it would never heal completely and it would be red and itchy again in a few days. After we started using Zymox Enzymatic Topical Spray, the results were immediate. We only had to use Zymox for 4 or 5 days, with one later application. The skin on her belly has now cleared up and is soft to the touch and does not itch. She no longer scratches. We think Zymox is great!

Rated 5 out of 5 stars
By KellyG on Aug 19, 2020

immediate relief

Our boxer has skin allergies that escalate so quickly that they get blistered, infected and ooze. It's terrible and so itchy and painful for him. We use this (in combination with Zymox shampoo & conditioner and skin ointment) and he literally feels IMMEDIATE relief. I spray AM & PM for a few days when it flares up and he quits licking (which means they can heal!!!) He hates the spray, but it's worth it for the relief he feels. It smells pleasant and isn't overwhelming.