Zymox Enzymatic Topical Spray with Hydrocortisone 0.5% for Dogs & Cats, 2-fl oz bottle

$10.72 First Time Autoship Price
this order
Save 35% (up to $20) on your first Autoship order. 

$16.49 Autoship Price
future orders
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$16.49 Chewy Price
($8.25 /fl oz)
Save $1.50 (-8%)
$17.99 List Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
Promo, Buy 3, Get 4th Free- Mix & Match

In Stock
FREE 1-3 day delivery on first-time orders over $35
Free 365-day returns

About This Item

Details

  • Gentle, enzymatic approach to first aid care for wounds, cuts, hot spots and even mild skin infections. It's so gentle, it's even suitable for kittens and puppies!
  • Contains hydrocortisone for inflammation and itch relief.
  • No pre-cleaning or scrubbing of the area before use.
  • LP3 Enzyme System reacts with the infectious pus and debris to form its antimicrobial properties.
  • Made in the USA.

Ingredients

Instructions

Learn More About Zymox From Our Team of Experts

Compare Similar Items

Zymox
Enzymatic Topical Spray with Hydrocortisone 0.5% for Dogs & Cats, 2-fl oz bottle
Zymox
Enzymatic Topical Spray with Hydrocortisone 0.5% for Dogs & Cats, 2-fl oz bottle
$16.49 Chewy Price
($8.25/fl oz)
Rated 4.6 out of 5 stars
200Reviews
Made In           
United States
United States
United States
Sourced From           
United States
United States
Ingredients           
Hydrocortisone 0.5%, Aloe Vera, Benzoic Acid, Benzyl Alcohol, Dipropylene Glycol, Glucose Oxidase, Glycerin, Isopropyl Myristate, Lactoferrin,
Active Ingredients: Hydrocortisone 1.0%., Inactive Ingredients: Aloe Vera, Benzoic Acid, Benzyl Alcohol, Dipropylene Glycol, Glucose Oxidase,
Active: Hydrocortisone 1%, Pramoxine Hydrochloride 0.5%, Inactive: Propylene Glycol, Water, SD Alcohol 40B, Glycerin, PEG-75 Lanolin, Hydrolyzed Oats,
Chlorhexidine Gluconate, Phospholipid Complex, PCMX, SDA 40, Polyoxyethylene Sorbitan Monolaurate, Purified Water.
Purified water, maltodextrin, vitamin E, bittering agent, sodium stearoyl glutamine, botanical fragrance of green apple, preservative.
Purified Water, Renewable Plant & Coconut-Derived Conditioner & Detangler, Colloidal Oatmeal, Vitamin E, Organic Aloe Vera, Panthenol, Botanical
Active Ingredients: Pramoxine Hydrochloride 1%, Inactive Ingredients: Purified Water, Oat Flour, Herbal Fragrance, Methylchlororisothiazolinone &
Purified Water, Renewable Plant & Coconut-Derived Conditioner & Detangler, Colloidal Oatmeal, Vitamin E, Organic Aloe Vera, Panthenol, Lavender Oil,
Purified Water, Renewable Plant & Coconut-Derived Conditioner & Detangler, Colloidal Oatmeal, Vitamin E, Organic Aloe Vera, Panthenol, Rosemary Oil,
Pramoxine Hydrochloride 1%.
Propylene Glycol Usp, Hydrocortisone Usp, Germaben Ii.
Water, Colloidal Oatmeal, Glycerin, Hydrolyzed Wheat Protein, Alpha Hydroxy, Ethanol Alcohol, Vitamin E, Vitamin B5, Beta Hydroxy, Emulsifier,
Health Feature           
Itch & Redness Remedy, Skin & Coat Health
Itch & Redness Remedy, Skin & Coat Health
Allergy Relief
Itch & Redness Remedy, Skin & Coat Health
Itch & Redness Remedy
Skin & Coat Health
Itch & Redness Remedy
Skin & Coat Health
Odor Control
Itch & Redness Remedy, Skin & Coat Health
Itch & Redness Remedy
Itch & Redness Remedy, Allergy Relief
Grooming Feature           

Questions & Answers

7 Customer Questions


Can I use this on dogs paws? Inbetween pads she licks constantly so it red


Will this make my cat sick if they lick the affected area after applying this product?

Answer by ChewyAug 11, 2018
While licking this spray wont cause sickness, you should prevent the pet from licking to allow it to dry.

can this product be used for ear infections on my dog?

Answer by ChewyJun 16, 2018
This product is formulated for wounds, cuts, hot spots and even mild skin infections, however, it is not recommended to be used for ear infections.

Can this be used long term on a cat with environmental allergies?

Answer by ChewyMay 13, 2020
It is recommended to use topical spray once daily up to 7 days. If condition persists or worsens for more than 7 days, stop use and consult a veterinarian.

4.6
Rated 4.6 out of 5 stars
200 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Durability

75% Positive

Ease of Use

92% Positive

Effectiveness

85% Positive

Safety

83% Positive

88 Customer Reviews



Rated 5 out of 5 stars
By Elizabeth on Oct 5, 2025

The best allergy/hot spot medicine

I have short-haired border collie who has seasonal allergies. Hot spots, dry skin, lots of scratching. This is the ONLY product I have ever used that stops all his

I have short-haired border collie who has seasonal allergies. Hot spots, dry skin, lots of scratching. This is the ONLY product I have ever used that stops all his symptoms. We do use salmon oil in his food daily, as well, but that doesn't stop symptoms on its own. It's a small bottle but you don't need much. I've re-ordered twice.


Rated 5 out of 5 stars
By Joan on Oct 10, 2025

Soothing for occasional irritation of outer ear.

Our GSD occasionally experiences reddening of the outer ear, possibly due to seasonal environmental sensitivities. This hydrocortisone is soothing and reduces the

Our GSD occasionally experiences reddening of the outer ear, possibly due to seasonal environmental sensitivities. This hydrocortisone is soothing and reduces the apparent inflammation.


Rated 5 out of 5 stars
By Bonnie on Sep 3, 2025

Great Product!

This spray stopped my dogs incessant scratching on his neck! It soothed whatever was itching, hurting or stinging him on his neck! After a few sprays the first day,

This spray stopped my dogs incessant scratching on his neck! It soothed whatever was itching, hurting or stinging him on his neck! After a few sprays the first day, I hardly had to spray him again. I'm happy to keep ZYMOX on hand in case the itching ever comes back!


Rated 5 out of 5 stars
By KC on Jul 27, 2025

It was working

It was working great until she got wise and for some reason she can smell the ointment and runs and hides. She is so difficult. It takes both my husband and myself

It was working great until she got wise and for some reason she can smell the ointment and runs and hides. She is so difficult. It takes both my husband and myself to apply it now


Rated 5 out of 5 stars
By Svetlana on Aug 10, 2025

Works very good on my cat!

I love Chewy very much! Always fast delivery, the best customer service!! Highly recommending their service!!! TY!!!

I love Chewy very much! Always fast delivery, the best customer service!! Highly recommending their service!!! TY!!!


Rated 5 out of 5 stars
By Sherrie on Jul 28, 2025

That it's a spray.

He doesn't mind being "wetted" with this. It's really helped with 'hot spots' and allergies.

He doesn't mind being "wetted" with this. It's really helped with 'hot spots' and allergies.


Rated 4 out of 5 stars
By Jessica on May 13, 2025

Great but pricey

It works well but I wish it was sold in a larger container! Also, the container tends to leak (it’s happened twice during shipping now).

It works well but I wish it was sold in a larger container! Also, the container tends to leak (it’s happened twice during shipping now).


Rated 5 out of 5 stars
By Danna on Oct 14, 2025

Great results!

Great for hot spots and itching!

Great for hot spots and itching!


Rated 5 out of 5 stars
By Laurie on Jul 23, 2025

Stopped the itch

This worked well tostop the itch and it healed right up.

This worked well tostop the itch and it healed right up.


Rated 5 out of 5 stars
By Letita on Jun 8, 2025

Recommend it

I love the price. It immediately stopped the scratching.

I love the price. It immediately stopped the scratching.