Zymox Topical Cream with Hydrocortisone 0.5% for Dogs & Cats, 1-fl oz bottle

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At a Glance

  • Skin & Coat Health
  • All Lifestages
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$15.99 Chewy Price
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$20.79 List Price
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About This Item

Details

  • Natural bio-active enzymes to aid in the treatment of skin infections, hot spots and wounds
  • Effective for topical use against: gram positive and gram negative bacteria; fungus and yeast; and resistant, difficult microorganisms including MRSA, ringworm and some viruses
  • 0.5% hydrocortisone helps relieve itch, discomfort and inflammation
  • Safe, gentle and non-toxic so it’s great for puppies and kittens all the way to adulthood
  • Made in the USA.

Ingredient Information

Instructions

Learn More About Zymox From Our Team of Experts

Frequently bought together

Questions & Answers

13 Customer Questions

My dog has a yeast infection would this help it? I have been giving her a bath with her prescribed shampoo but it’s not doing anything.

Answer by Chewy • Jan 20, 2018
This product is a natural bio-active enzymes to aid in the treatment of skin infections, hot spots and wounds. This topical effectively for topical use against: gram positive and gram negative bacteria; fungus and yeast; and resistant, difficult microorganisms including MRSA, ringworm and some viruses.

Can this be used for cat chin acne?

Answer by Chewy • Jun 05, 2019
This topical cream is not intended to help with cat chin acne.

Does it sting or burn when applied to problem areas ?

Answer by Chewy • Aug 19, 2020
This cream is safe, gentle, and non-toxic and is for topical use only.

Does the application have to be covered to keep the dog from licking it?

Answer by Chewy • Aug 21, 2023
This cream is non-toxic and worry-free if licked.
Reviews
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4.6
Rated 4.6 out of 5 stars
169 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

89% Positive

Effectiveness

88% Positive

Ingredients

92% Positive

Long-Term Benefits

88% Positive

77 Customer Reviews

Rated 5 out of 5 stars
By Melissa on Sep 25, 2025

Buy this one!

We live in florida so my poor pupper gets more than her fair share of mosquito bites on walks and then proceeded to scratch and bite at them. I swear after the first

We live in florida so my poor pupper gets more than her fair share of mosquito bites on walks and then proceeded to scratch and bite at them. I swear after the first application she was already getting so much itch relief and now after a few days her skin is almost 100% and she has fully stopped biting and scratching her skin! BUY THIS ONE

Rated 5 out of 5 stars
By Samantha on Aug 11, 2025

Itch Skin

i got this in hopes my poor Lola would feel better. she had almost like a hot spot on her back, it was red and irritated. she was missing hair and you could tell

i got this in hopes my poor Lola would feel better. she had almost like a hot spot on her back, it was red and irritated. she was missing hair and you could tell it bothered her. to save a trip to the vet, i got this. just by day one i could see it working. im not going to lie, i skipped a few days before i would add some again but still. after 2 days the redness was gone and she had scabs, which meant it was healing. i added more and now its gone! all her hair is back and she isnt constantly licking the area.

Rated 1 out of 5 stars
By Ashton on Oct 7, 2025

Don’t work

Got this for my dog for a place she had on her stomach and it actually ended up making it worse and the vet had to give us a prescription for antibiotics to help

Got this for my dog for a place she had on her stomach and it actually ended up making it worse and the vet had to give us a prescription for antibiotics to help it heal up because the ointment made it worse

Rated 5 out of 5 stars
By Chet on Jul 11, 2025

Works extremely well and fast

My pup had some sort of dermtitis from either moisture or allergies under the axilla . It was incredibly itchy and red bumps with slight drainage. My go-to is usually

My pup had some sort of dermtitis from either moisture or allergies under the axilla . It was incredibly itchy and red bumps with slight drainage. My go-to is usually silver honey and while it did work and cut down the inflammation, it would wear off by days end. I applied it 3 times a dayfor 2 weeks and it just coming back. Purchased this out of despiration before going to a prescription genone spray or animax ointment. The redness and raised skin was gone in 3 days with twice a day application. A little goes a long way. I will forever keep this in my dogs medicine cabinet for now on.

Rated 5 out of 5 stars
By Sara on Oct 12, 2025

Good Topical Cream

I really like this brand. It helped with my dog’s allergies and dryness.

I really like this brand. It helped with my dog’s allergies and dryness.

Rated 5 out of 5 stars
By Gail on Jul 20, 2025

Easy to apply and quickly absorbed on area applications to.

My small dog got immediate relief from the itchy, scaling redness on her legs neck and under arms. With daily use she is quite comfortable and itch free.

My small dog got immediate relief from the itchy, scaling redness on her legs neck and under arms. With daily use she is quite comfortable and itch free.

Rated 5 out of 5 stars
By Bethany on Aug 25, 2025

That it helped with my dogs ears. It was not that hard to put on

This is a great product, and the fact that my dog is feeling better helps a lot.

This is a great product, and the fact that my dog is feeling better helps a lot.

Rated 3 out of 5 stars
By Theresa on Aug 9, 2025

Worked fairly well. Easy to apply.

It seemed to give our dogs some relief from irritation on paws.

It seemed to give our dogs some relief from irritation on paws.

Rated 2 out of 5 stars
By Annette on Aug 26, 2025

It didn’t work as I would hope

I wanted it to help her paws from chewing on them.

I wanted it to help her paws from chewing on them.

Rated 5 out of 5 stars
By My on Dec 18, 2024

Does What It Says!

I was skeptical that this would work when nothing else except prescription medication and tons of Benadryl would work for my pooch who's had environmental allergies/contact

I was skeptical that this would work when nothing else except prescription medication and tons of Benadryl would work for my pooch who's had environmental allergies/contact dermatitis for all of her precious 8 years of life. What did I have to lose by trying this after seeing the ratings and reading the the good and bad reviews? Absolutely nothing. Glad I took that chance! Not only have I not had to put her back on prescription meds, she's also not taking Benadryl as frequently as she used to! She knows it's helping, because she doesn't run from me when I go to put it on her. The only thing she sort of dislikes is having to wear her plush cone for about 30 minutes to keep her from licking it off. She doesn't even mind that so much anymore since she knows she won't have the itchies when I take the cone off.