Zymox Ear Infection Solution with .5% Hydrocortisone for Dogs & Cats, 1.25-oz bottle
By Zymox
$22.49Chewy Price
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$29.99Chewy Price
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$21.37Autoship Price
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About ZYMOX Enzymes for Healthy Ears and Skin


Antimicrobial and Antifungal Care
ZYMOX empowers pet parents with patented formulations of natural enzymes to help treat chronic infections in dogs, cats and horses. Their products are formulated to be safe to use on any age pet. ZYMOX packs a potent antimicrobial punch that targets the source of infections—bacteria and fungus(including yeast) to provide therapeutic relief, care, protection and prevention, without any antibiotics or harsh chemicals. Proudly made in the USA and endorsed by TICA (The International Cat Association).
Committed to Healthy Ears, Skin and Coat, and Smiles
To ensure overall health from snout to tail on all four-legged pals, Zymox has developed products that are specially formulated for all the areas that commonly need infection relief, like the ears, teeth and gums, and skin and coat.

Ear Care Solutions
Effective, non-toxic solutions with special enzymes and mild cleansers to keep ears clean and fresh, and combat microbes that can cause ear infections.

Oral Care Solutions
Brushless solutions with unique enzymes to dissolve plaque and prevent its buildup, boost natural "good bacteria," and protect against gum disease to keep kitty and doggy smiles healthy.

Skin and Coat Health
Topical sprays and shampoos for dogs, cats and horses that form a powerful protective barrier against minor skin inflammations from bacteria and fungi, while cleaning and conditioning the coat—with some formulas utilizing hydrocortisone.
100% Safe, Gentle and Easy
Because Zymox formulas are made with 100% naturally derived enzymes from dairy, they are safe for anytime use, both for immediate soothing relief and to prevent infections. The powerful enzymes work to eliminate problem single-celled organisms such as bacteria, fungi and yeast, while leaving healthy cells untouched. This means no irritations for your pal!


Enzyme-Based and Antibiotic-Free
Zymox products use a patented, gentle formulation that combines three potent, naturally occurring enzymes—lactoperoxidase, lysozyme and lactoferrin—that are sourced from milk products. These enzymes are proven to work together to eliminate the source of infection on your pet, without any toxins or antibiotics that can irritate or cause antibiotic resistance.
About ZYMOX
Zymox was founded in 1998 by Pamela Bosco, who sought to change the way that people treated and managed ear, oral and skin infections with a safer alternative to antibiotics. Enlisting the help of her brother—a scientist that developed the enzyme technology in Biotene—Bosco formulated a powerful enzyme-based solution to help treat infections in dogs, cats and horses with no toxins, chemicals or antibiotics. Committed to keeping all four-legged pals healthy, they offer USA-made and sourced products to treat, soothe and protect against bacterial and fungal infections gently and 100% naturally.
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Customer Rating | |||||
Price | $22.49Chewy Price | $23.79Chewy Price | $29.99Chewy Price | $15.99Chewy Price | $22.49Chewy Price |
Autoship | $21.37Chewy Price | $22.60Chewy Price | $28.49Chewy Price | — | $21.37Chewy Price |
Top Ingredients | N/A | Active Ingredients: Hydrocortisone 1%., Inactive Ingredients: Benzyl Alcohol, Dextrose... | Benzyl Alcohol, Beta-Glucanase, Cellulase... | Deionized Water, Isopropyl Alcohol, Polysorbate 20... | Active: Sd-Alcohol 40-2, 10%; Lactic Acid, 1.76%; Benzoic Acid... |
Breed Size | N/A | N/A | N/A | Small Breeds, Medium Breeds, Large Breeds | N/A |
Health Feature | Ear Care | Ear Care | Ear Care | Ear Care | Ear Care |
Lifestage | Adult | Adult | Adult | Adult | Adult |
19 Customer Questions
What is the difference between this and the one that has 1% hydrocortisone?
Answer by • Feb 04, 2018
This Solution contains 0.5% Hydrocortisone. The Zymox Plus Advanced Formula 1% Hydrocortisone Otic Dog & Cat Ear Solution has a higher level of hydrocortisone for more serious cases.
Can i use it once a week after treatment to maintain ?
Answer by • Oct 17, 2019
Zymox Ear Solution is intended to eradicate a broad range of infections ranging from mild to severe, but many veterinarians have also found Zymox Ear Solution to be effective in maintenance of the ears, especially during the allergy season.
Is this safe to use inside of a dog’s ear?
Answer by • Feb 11, 2019
This was meant to be applied liberally to un-cleaned ear, filling ear canal.
I have german shepards who are shaking their heads and itching even small red bumps. Is this somethingI could use on them? They stay inside most of the time except to go the bathroom. Help
Answer by • Sep 06, 2017
This Solution is designed to be highly effective for aiding in the treatment of bacterial, fungal and yeast infections including Staphylococcus, Pseudomonas, Proteus and Malassezia. We encourage speaking with your Veterinarian to assist with a diagnosis, for the safest opinion.