Zymox Topical Cream Inflammation Relief Hydrocortisone 1.0% for Dogs & Cats
By Zymox
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About ZYMOX Enzymes for Healthy Ears and Skin


Antimicrobial and Antifungal Care
ZYMOX empowers pet parents with patented formulations of natural enzymes to help treat chronic infections in dogs, cats and horses. Their products are formulated to be safe to use on any age pet. ZYMOX packs a potent antimicrobial punch that targets the source of infections—bacteria and fungus(including yeast) to provide therapeutic relief, care, protection and prevention, without any antibiotics or harsh chemicals. Proudly made in the USA and endorsed by TICA (The International Cat Association).
Committed to Healthy Ears, Skin and Coat, and Smiles
To ensure overall health from snout to tail on all four-legged pals, Zymox has developed products that are specially formulated for all the areas that commonly need infection relief, like the ears, teeth and gums, and skin and coat.

Ear Care Solutions
Effective, non-toxic solutions with special enzymes and mild cleansers to keep ears clean and fresh, and combat microbes that can cause ear infections.

Oral Care Solutions
Brushless solutions with unique enzymes to dissolve plaque and prevent its buildup, boost natural "good bacteria," and protect against gum disease to keep kitty and doggy smiles healthy.

Skin and Coat Health
Topical sprays and shampoos for dogs, cats and horses that form a powerful protective barrier against minor skin inflammations from bacteria and fungi, while cleaning and conditioning the coat—with some formulas utilizing hydrocortisone.
100% Safe, Gentle and Easy
Because Zymox formulas are made with 100% naturally derived enzymes from dairy, they are safe for anytime use, both for immediate soothing relief and to prevent infections. The powerful enzymes work to eliminate problem single-celled organisms such as bacteria, fungi and yeast, while leaving healthy cells untouched. This means no irritations for your pal!


Enzyme-Based and Antibiotic-Free
Zymox products use a patented, gentle formulation that combines three potent, naturally occurring enzymes—lactoperoxidase, lysozyme and lactoferrin—that are sourced from milk products. These enzymes are proven to work together to eliminate the source of infection on your pet, without any toxins or antibiotics that can irritate or cause antibiotic resistance.
About ZYMOX
Zymox was founded in 1998 by Pamela Bosco, who sought to change the way that people treated and managed ear, oral and skin infections with a safer alternative to antibiotics. Enlisting the help of her brother—a scientist that developed the enzyme technology in Biotene—Bosco formulated a powerful enzyme-based solution to help treat infections in dogs, cats and horses with no toxins, chemicals or antibiotics. Committed to keeping all four-legged pals healthy, they offer USA-made and sourced products to treat, soothe and protect against bacterial and fungal infections gently and 100% naturally.

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21 Customer Questions
My dog has been biting and licking underneath his tail near the anal area - is this safe to use to provide some relief?
Answer by • May 19, 2018
This Topical Cream can be used to treat the external anal area.
Can it be applied to my dog's paws?
Answer by • Dec 19, 2018
This product can be used on your dog's paws for itch relief.
Will this particular product help with mange or hair loss?
Answer by • Apr 20, 2018
This product isn't intended to treat mange or reverse hair loss. We recommend consulting a veterinary professional for the best for of treatment.
Can you use this cream longer than 2 weeks?
Answer by • Sep 16, 2020
The manufacturer recommends applying this topical cream to the affected area once daily or as needed for one to two weeks. If you'd like to use it for more than two weeks we recommend consulting your veterinarian for the best course of action.














