Apoquel (oclacitinib) Tablets for Dogs

By Apoquel
Rated 4.621 out of 5 stars
Prescription Item


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$2.70Chewy Price
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About This Item


Apoquel is an oral tablet that works differently than other allergy medications. It goes straight to the source to help relieve itch and inflammation at its core—addressing the underlying cause of irritation and soothing allergic reactions. It starts to relieve those unpleasant symptoms within 4 hours, and effectively controls itching within 24. Apoquel is ideal for both short or long-term treatment and can help to offer relief without many of the side effects associated with steroids.

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Play Video: Learn More About Apoquel From Our Team of Experts
Learn More About Apoquel From Our Team of Experts

About Apoquel Tablets for Dogs

Relief for Your Itchy Dog

For dogs with allergic itch, relief can’t come soon enough. Apoquel (oclacitinib tablet) provides fast, safe relief from itching—so you and your dog can get back to doing what you love.

Fast Acting

If your dog is scratching, licking or chewing like crazy, you want to provide relief that starts acting quickly. Apoquel starts relieving allergic dog itch within 4 hours and helps control itch within 24 hrs.

Targets Itch at the Source

Apoquel goes right to the source of allergic itch, to help stop itching and relieve associated inflammation in affected canines.

9 Million Dogs and Counting

You can have peace of mind knowing that your dog is in good company—9 million dogs (and counting) have already had their allergic itch treated with Apoquel. Your dog could be next!


Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. See full Prescribing Information.
Prescribing Information


Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.


Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25(6):512-518, e86. doi: 10.1111/vde.12166. Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479-e114. doi: 10.1111/vde.12047.) Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35.5. Cosgrove SB, Wren JA, Cleaver DM, et al. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel®) in client-owned dogs with atopic dermatitis. Vet Dermatol. 2013;24(6):587-e142. Data on file, Unique Patient Count from Launch, 2020, Zoetis Inc.

About Apoquel

Apoquel is a revolutionary medicine for allergic itch in dogs. It targets the issue at its source, to help relieve itch and inflammation in dogs 12 months and older. Apoquel begins providing relief in 4 hours and helps control the itch within 24 hours. It can be used for long-term maintenance therapy or short-term relief and has been used on over 9 million dogs. For itch relief worth barking about, try Apoquel, your allergic dog’s new best friend!
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ReviewsWrite a Review

Rated 4.621 out of 5 stars
2388 Ratings
Would recommend to a friend

2375 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Pokey1 on Aug 30, 2023

No More Excessive Itching!

My German Shepard has environmental and seasonal allergies. Mr. Loki Pokes is a rescue, and when I brought him home in the summer 2022, he was in bad condition. He was itching his skin off and had scabs and scars, but no fleas. It was so bad he couldn't get a drink of water without stopping to scratch a few times. After trying baths, changing his diet, and every home remedy on the internet, his veterinarian put him on Apoquel. We haven't looked back. At first, he needed it every day. Now, he only takes it when needed - when spring comes and usually the day of, and after mowing the lawn. I suspect he will need it during the fall for a while as well. This drug is wonderful. He is not the same dog. It has totally given him a better quality of life, and for that, we are both grateful.

Rated 3 out of 5 stars
By NeverReceived on Aug 23, 2023

This product works great for my dog. minimizes her chewing/itching within a couple days of using daily. I usually get it from my local vet, but tried Chewy because it’s cheaper. Unfortunately, my very first order was stolen shortly after delivery while I was at work. The process to get it replaced looked to be more complex than I hoped for. Will not be ordering medication online again. Not worth watching my dog go weeks with discomfort while I figure out how to get a replacement. Would prefer it to be mailed USPS. * I will note, others must know this product works, since it has been the only item stolen off my front porch.

Rated 4 out of 5 stars
By AJJ13 on Sep 7, 2023
Top 50 Contributor

Worked for 1 dog, not the other

We have one dog with major skin issues and she has been on Apoquel for many years now. We attempted to stop using it and taper her off, but boy did her skin problems return! So thankful it works wonders for her. We have another dog with a grass allergy that just chews her feet. Apoquel did nothing for her. Regardless, we would definitely recommend trying it at least. It is great when it works and it makes for a happy dog!

Rated 5 out of 5 stars
By Riley on Sep 16, 2023

The only thing that works for seasonal allergies

My corgi riley has seasonal allergies that flare from august and lasts a couple months. she gets hot spots on her paws and armpit area. steroids and cytopoint did not work but apoquel did. It's pricey but i only get enough for 2 months then she's fine. this treatment combined with a medicated fungal spray should be all you need.

Rated 5 out of 5 stars
By MK on Sep 11, 2023

Game Changer

This really helped my french bulldog who has been suffering from all sorts of allergies since he was a puppy. Within a week the skin bumps went away, he had way less nasal and eye drainage, and he wasn’t licking and biting at his paws. I still combine this with a daily Zyrtec and an HP diet dog food. But I’m so glad he finally has relief!

Rated 5 out of 5 stars
By Tory on Aug 27, 2023

Working wonders for my dog!

My Labradoodle is seven years old and although she isn’t a puppy anymore, she still has a lot of life in her. This last nine months or so she has been having a harder time getting up on the couch or the bed after a good day of play. When it started becoming more frequent, the vet suggested I try apoquel. She is doing so much better now! It’s nice to know that she can have a day of fun and not have to suffer for it later.

Rated 4 out of 5 stars
By Kel on Aug 31, 2023

Great service

I had some issues with the vet and the pharmacy staff and helped me resolve it quickly! The only reason I gave 4 stars is because one of the techs called me the next day to tell me it had been rejected. it apparently was in a bin and she did not check the computer before calling me! I work night she so she woke me up with incorrect information. Grrrr

Rated 3 out of 5 stars
By great on Sep 16, 2023

worked great but..

This product worked great for my dogs allergies BUT after doing more research on this drug, I quickly stopped the auto-ship. Please do your own research about what it does to your dogs body / immune system. Like I said worked great but is not a long time fix whatsoever.

Rated 4 out of 5 stars
By Andrew on Sep 12, 2023

Itch-Free Journey

I've had a fantastic experience with this product for my dog. It's been remarkably effective in reducing her itching and chewing within just a few days of daily use. Typically, I purchase it directly from my local vet, but I decided to give Chewy a try due to the lower price.

Rated 5 out of 5 stars
By Bigpaws1 on Sep 7, 2023

Excellent for Skin Allergies

We use this product for hotspots and anytime our Saint Bernard starts scratching. You can stop & start this drug without side effects. We were using Prednisone but it is not a drug you can just stop and start your dog has to slowly come off it.