Apoquel (oclacitinib) Tablets for Dogs

By Apoquel
Rated 4.6303 out of 5 stars
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$2.70Chewy Price
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About This Item


Apoquel is an oral tablet that works differently than other allergy medications. It goes straight to the source to help relieve itch and inflammation at its core—addressing the underlying cause of irritation and soothing allergic reactions. It starts to relieve those unpleasant symptoms within 4 hours, and effectively controls itching within 24. Apoquel is ideal for both short or long-term treatment and can help to offer relief without many of the side effects associated with steroids.

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Learn More About Apoquel From Our Team of Experts

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This Item – Apoquel (oclacitinib) Tablets for Dogs, 16-mg, 1 tablet
Rated 4.6303 out of 5 stars
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About Apoquel Tablets for Dogs

Relief for Your Itchy Dog

For dogs with allergic itch, relief can’t come soon enough. Apoquel (oclacitinib tablet) provides fast, safe relief from itching—so you and your dog can get back to doing what you love.

Fast Acting

If your dog is scratching, licking or chewing like crazy, you want to provide relief that starts acting quickly. Apoquel starts relieving allergic dog itch within 4 hours and helps control itch within 24 hrs.

Targets Itch at the Source

Apoquel goes right to the source of allergic itch, to help stop itching and relieve associated inflammation in affected canines.

9 Million Dogs and Counting

You can have peace of mind knowing that your dog is in good company—9 million dogs (and counting) have already had their allergic itch treated with Apoquel. Your dog could be next!


Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. See full Prescribing Information.
Prescribing Information


Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.


Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25(6):512-518, e86. doi: 10.1111/vde.12166. Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479-e114. doi: 10.1111/vde.12047.) Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35.5. Cosgrove SB, Wren JA, Cleaver DM, et al. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel®) in client-owned dogs with atopic dermatitis. Vet Dermatol. 2013;24(6):587-e142. Data on file, Unique Patient Count from Launch, 2020, Zoetis Inc.

About Apoquel

Apoquel is a revolutionary medicine for allergic itch in dogs. It targets the issue at its source, to help relieve itch and inflammation in dogs 12 months and older. Apoquel begins providing relief in 4 hours and helps control the itch within 24 hours. It can be used for long-term maintenance therapy or short-term relief and has been used on over 9 million dogs. For itch relief worth barking about, try Apoquel, your allergic dog’s new best friend!
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ReviewsWrite a Review

Rated 4.6303 out of 5 stars
2643 Ratings
Would recommend to a friend

2537 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Tyler on Nov 13, 2023

The last medication my elderly dog will ever take

My 14 y/o Olde English Bulldogge, Zilla, has struggled with skin/stomach/eye/ear/paw issues for a majority of her adult life. After 10s of thousands of dollars spent on pet insurance, vet bills, and medications, it finally feels like I've found a real solution. It's not a cheap solution, but it's cheaper and actually works without going through the yo-yoing of putting her on antibiotics/steroids when things went from bad to worse and then running out and having her go back to being miserable. Apoquel has COMPLETELY resolved ALL of Zilla's skin issues. All of her neck and belly hair has grown back, her ears are no longer swollen/smelly/eminent infection (she can hear again!), and the space between the pads of her paws look like they did when she was a puppy. No more sneezing and her eyes are less red and irritated. The only side effect I've seen, other than all the positive ones, is dry mouth. I don't usually leave reviews but felt driven to share given the life changing effect it's had for my old girl. It's a no-brainer for me despite it's price--given her age and wanting to make the absolute most of her golden years.

Rated 4 out of 5 stars
By Mark on Nov 22, 2023

Beware when ordering, get more than 1.

Ordering is convenient, saving a trip to the vets office. Chewy contacts the vet to approve the script. Price isn't great but I guess it compares favorably to the vets office. Beware, this pill is an everyday pill for dog allergies, I have no idea why Chewy has the default option being to order a single pill. I don't know why that option is there at all. Who would order a single capsule of an everyday pill? Chewy did notice the error and cancelled my single pill order. They sent an email to notify me of the fact but, since I don't check email that often, it made my dog go a few days without her allergy meds.

Rated 5 out of 5 stars
By Courtney on Nov 3, 2023


We adopted a 1 year old Pitbull in August 2023. We’ve had Pitbulls before, but none with the dreaded allergy issues. When we adopted him the first thing I noticed was his green goopy eyes. Especially in the mornings. He eventually developed a constant itch. He started to lose hair in spots (mostly around his neck and shoulders. His chest and his belly were constantly red with bumps. We even changed his food to a sensitive skin and stomach food since he has both and we had no relief. I tried all the usual home remedies (Benadryl, allergy supplements, medicated baths, coconut oil, etc. ) nothing worked. We started Apoquel a month ago and it’s been amazing to see him get relief. We noticed a difference within the first few days. He only takes this once a day, so it does make the price doable. I will admit when the vet recommended this I was hesitant because I looked up the price before even going. I’m so glad I bit the bullet and tried it. Highly recommend!

Rated 5 out of 5 stars
By Alyce on Nov 18, 2023

Helps stop itching

My gunner is 4 years old and has the typical gsd dry and itchy skin throughout winter months. I found this to work very well however it’s definitely pricey. It does stop him from itching and licking throughout the day. I also have a hot spot spray. I have tried salmon oil on his food but he very picky. Beware that it is pill form. I smoosh cheese around it for him to eat it lol

Rated 5 out of 5 stars
By Linda on Nov 6, 2023

They work, at least for us

Was not happy about cost, but since Zoetis still has sole control will have to deal with that and be happy our semi-pug is no longer scratching himself raw. Hard to think of those who do not have the financial resources to make a comfortable decision. Chewy had competitive pricing and totally awesome service. This is my first order for a repeat scheduled order delivery , but expecting the same satisfaction as with other single orders for food, litter, etc over past years.

Rated 5 out of 5 stars
By Cynthia on Nov 9, 2023

This was a godsend

My senior dog had a raw spot on her belly that she kept licking. She was losing fur on her belly in big patches. The vet tried Bravecto first, thinking it might be mites. Then ordered a thyroid test which came back normal. He gave her antibiotics along with an antifungal and Apoquel and it did the trick. Healed her completely and now she just has to take the Apoquel daily for maintenance. She remains allergy free and a very happy senior!

Rated 5 out of 5 stars
By Libde on Oct 25, 2023

Best thing I’ve ever done for my dog!

Both of our basset hounds, have seasonal allergies, regular skin conditions, musky smell, itching, and shedding. I started this med to alleviate some deep fissures on one of my Bassets feet, but in the end, it cured all of her skin conditions. We started our other Bassett on it, and the same thing happened. This is an allergy medicine, and it did its job! However, our dogs also have ortho problems and arthritis. The medicine is also reported to have some auto immune effects, and we found this to be true as well! They are feeling better from allergies and arthritis. I would recommend and will continue to use!

Rated 5 out of 5 stars
By Barbara on Nov 14, 2023

Chewy delivery

Very happy with the speed and fulfillment of my order. I would like to add though that when I order a large bag of dog food, I am disappointed the delivery is left at my gate and not brought to the door. This is not a chewy problem but a delivery problem. When I am home alone it is hard to get such a heavy item to the door which cannot be left out in the Arizona sun until I can get help

Rated 5 out of 5 stars
By Deven on Nov 1, 2023

Super Easy

My dog needs to take Apoquel during the spring and fall seasons for allergies that cause her to scratch really bad. I've tried benadryl and zyrtec which my vet recommended prior to using Apoquel. Unfortunately it seems like this is the only thing that works (pill wise). Using Chewy for prescriptions has made it super easy. I think it took like 4 days for everything to get finalized and the package to my doorstep. Now that the perscription is on file I'm sure reorders will be quick and painless.

Rated 2 out of 5 stars
By David on Oct 18, 2023

Apoquel does not work for our dog.

Apoquel is a very expensive brand drug at almost $3.00 per dose. We found it not to be effective in treating our 8 year old Maltese. We have had to treat her with antibiotics to eliminate allergy sores on her back (particularly around her tail). She constantly chews her feet until they are raw. Our Vet now has resorted to allergy injections every two months. We have been dealing with her allergies for over three years now. We use medicated shampoos and sprays along with antibiotics to treat the sores and allergy injections to reduce paw chewing. Nothing works for long. Have not had positive results with Apoquel.