Optimmune (0.2% Cyclosporine) Ophthalmic Ointment for Dogs, 3.5-g

By Optimmune
Rated 4.3458 out of 5 stars
Prescription Item
$63.99 Chewy Price
In Stock
FREE delivery
Usually arrives in 3-5 days
We'll collect your pet's prescription information at Checkout.

This item requires prescription approval.

Medications ship separately. Delivery times may vary.

About This Item


Optimmune is an eye ointment that contains cyclosporine. It is used for the management of chronic keratoconjunctivitis sicca (KCS or dry eye) and chronic superficial keratitis (CSK). This preservative-free ointment reduces the chances of chemical irritation and secondary infection, and can be stored for 24 months without refrigeration.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Learn More About Optimmune From Our Team of Experts

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ReviewsWrite a Review

Rated 4.3458 out of 5 stars
214 Ratings
Would recommend to a friend

203 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 3 out of 5 stars
By Karen on Nov 22, 2023

Good product, but too much packaging!

My order from Chewy was for prescription eye drops for my dog. The delivery was fine, as was the product, but the packaging was ridiculous. A tiny tube of eye drops was in a box, which was put in a large plastic pill bottle, which was put into a large cardboard box, with packing material. From now on I will get them from my vet, because I hate creating all of this extra packaging for a tiny tube of eye drops. The drops could have been sent in a padded envelope. I love Chewy, but they need to be more environmentally friendly.

Rated 2 out of 5 stars
By Shannon on Nov 23, 2023

Price Keeps Increasing

This medication is very expensive and the price keeps going up. Chewy’s price started reasonably however it’s getting close to what the vet is charging. We’re looking for another online source for pet meds now.

Rated 5 out of 5 stars
By Dilwantie on Nov 6, 2023


but good. Been using this ointment for a few years. Easy to administer as he had bleeding in left eye - but also using in both eyes, Condition is stable. PET is 16- and vision has diminished but this is for his lifetime and no adverse reaction to it.

Rated 5 out of 5 stars
By Judie on Nov 3, 2023

Optimmune Ophthalmic Ointment for Dogs

My dog, Lilly, has an eye condition that requires the above medication. I appreciate how quickly I received my order after placing it. Thank you, Chewy, for making it easy to order from your service.

Rated 5 out of 5 stars
By Susan on Nov 18, 2023

Ointment for dog's eyes

My order was for a special ointment for my dog's autoimune eye infection.and delivered promptly. Recommend as needed. It is expensive but necessary to treat Pannus.

Rated 4 out of 5 stars
By Dog on Aug 24, 2023

Blinking/Squinting Eyes

My dog has keratoconjunctivitis sicca (KCS, dry eye) so he needs this RX medicine twice a day. He is also on Refresh Tears which I have to give 20min apart from one another. The Optimmune makes my dogs eyes blink/squint more after giving him the medicine. He sometimes paws at his eyes and licks his legs. My vet said Optimmune can cause some eyelid spasming and some local irritation, but I think most dogs get used to this. He said to keep using Optimmune since we know it helps to reduce the risk of corneal inflammation and secondary infection in the dogs with KCS.

Rated 5 out of 5 stars
By Mary on Sep 14, 2023

saved money

Savannah has been on Optimmune for 20 months due to an eye injury. It appears she will have to continue indefinitely. This is the second tube I received from Chewy. I am saving $24 each tube. I wish I started 19 months ago. She is also on another medication that is cheaper with Chewy.

Rated 5 out of 5 stars
By Roberta on Oct 9, 2023

Optimunne eye medicine

Prescribed by my vet early 2023 the daily ointment has been very effective for my dog. It is a prescription medication. Chewy Pharmacy is always very quick at getting medications to me

Rated 3 out of 5 stars
By MalteseMom on Sep 5, 2023

Ophthalmic Ointment for dogs

This stuff is great. It gives my dog great relief from her dry eyes BUT it is very expensive for the amount of product that you get. I use, approved by my vet, OTC eye drops that I alternate back and forth.

Rated 2 out of 5 stars
By Jarenie on Nov 12, 2023


The first tube of med was full. This one I had to flatten half of the tube before any meds came out.