10 Best Dog Itch Relief & Hot Spot Treatments 2025: According to Reviews | Chewy

The 10 Best Dog Itch Relief & Hot Spot Treatments

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How we created this dog itch relief & hot spot treatment list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best dog itch relief & hot spot treatment.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best dog itch relief & hot spot treatments.

Key dog itch relief & hot spot treatment considerations

Ease of use

Effectiveness

Ingredients

Long-lasting relief

1
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar

Musher's Secret Paw Protection Natural Dog Wax, 60-g jar

Rated 4.7 out of 5 stars
2,008
$15.99Chewy Price
($0.27/g)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Ingredients

4.6/5
Excellent

Long-lasting relief

4.7/5
Excellent

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

White and Yellow Beeswax, Carnauba, and Candelilla Wax and White and Vegetable Oils with Vitamin E

Health Feature

Itch & Redness Remedy, Paw Care, Hoof Care
2
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle

Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle

Rated 4.7 out of 5 stars
1,077
$16.99Chewy Price
($1.07/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.7/5
Excellent

Effectiveness

4.7/5
Excellent

Ingredients

4.6/5
Excellent

Long-lasting relief

4.4/5
Great

Is this dog itch relief & hot spot treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Purified water, colloidal oatmeal, renewable plant-derived & coconut-based cleansers, organic aloe vera, vitamins A

Health Feature

Itch & Redness Remedy
3
Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin
Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin
Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin
Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin
Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin
Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin

Natural Dog Company Paw Soother Dog Paw Balm, 1-fl oz tin

Rated 4.6 out of 5 stars
291
$15.49Chewy Price
($15.49/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.4/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.3/5
Great

Long-lasting relief

4.5/5
Great

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Organic Mango Butter, Organic Cocoa Butter, Organic Coconut Oil, Organic Hempseed Oil, Organic Jojoba Oil

Health Feature

Paw Care
4
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle

Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle

Rated 4.7 out of 5 stars
463
$21.99Chewy Price
($1.38/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.5/5
Great

Effectiveness

4.6/5
Excellent

Ingredients

4.6/5
Excellent

Long-lasting relief

4.4/5
Great

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Chlorhexidine Gluconate, Ketoconazole, Water, Lauramine Oxide, Polyacrylate-1 Crosspolymer

Health Feature

Anti-Fungal / Anti-Bacterial, Itch & Redness Remedy
5
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube
Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube

Bag Balm Pet Nose, Paw & Hot Spot Moisturizer, 2-fl oz, tube

Rated 4.5 out of 5 stars
1,185
$4.97Chewy Price
($2.49/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.4/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.4/5
Great

Long-lasting relief

4.6/5
Excellent

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Petrolatum, Lanolin, 8-Hydroxyquinoline Sulfate 0.3%, Paraffin Wax

Health Feature

Skin & Coat Health, Paw Care
6
The Blissful Dog Every Dog Nose Butter, 2-fl oz tin
The Blissful Dog Every Dog Nose Butter, 2-fl oz tin
The Blissful Dog Every Dog Nose Butter, 2-fl oz tin
The Blissful Dog Every Dog Nose Butter, 2-fl oz tin
The Blissful Dog Every Dog Nose Butter, 2-fl oz tin

The Blissful Dog Every Dog Nose Butter, 2-fl oz tin

Rated 4.7 out of 5 stars
282
$13.99Chewy Price
($7.00/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.6/5
Excellent

Effectiveness

4.7/5
Excellent

Ingredients

4.6/5
Excellent

Long-lasting relief

4.6/5
Excellent

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Shea Butter, Castor Oil, Olive Oil, Almond Oil, Coconut Oil

Health Feature

Skin & Coat Health
7
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz
Sulfodene 3-Way Ointment for Dogs, 2-oz

Sulfodene 3-Way Ointment for Dogs, 2-oz

Rated 4.5 out of 5 stars
1,480
$9.26Chewy Price
($4.63/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.4/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.3/5
Great

Long-lasting relief

4.4/5
Great

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients : Benzocaine 1.5%, Salicylic Acid 1.6%., Inactive Ingredients: Menthol, Sorbitan Monooleate, Polysorbate 80

Health Feature

First Aid
8
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar
Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar

Pet MD Paw Balm 3-in-1 Nose/Snout & Elbow Moisturizer & Paw Protectors Paw Wax with Shea Butter, Coconut Oil, & Beeswax for Dogs, 2-fl oz jar

Rated 4.6 out of 5 stars
551
$15.49Chewy Price
($7.75/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.6/5
Excellent

Effectiveness

4.5/5
Great

Ingredients

4.5/5
Great

Long-lasting relief

4.6/5
Excellent

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Shea Butter, Olive Oil, Almond Oil, Coconut Oil, Beeswax

Health Feature

Skin & Coat Health
9
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray

Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8-fl oz spray

Rated 4.4 out of 5 stars
1,561
$9.97Chewy Price
($1.25/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.3/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.4/5
Great

Long-lasting relief

4.4/5
Great

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

Small Breeds, Extra Small Breeds, Medium Breeds, Giant Breeds...

Lifestage

All Lifestages, Adult

Top Ingredients

Purified Water, Glycerin, Polysorbate-20, Lidocaine HCI, Allantoin

Health Feature

Itch & Redness Remedy, Skin & Coat Health
10
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count
GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count

GoodGrowlies Allergy Relief & Itch Relief with Omega 3 Skin & Coat with Alaskan Fish Oil Chew Supplement for Dogs, 180 count

Rated 4.4 out of 5 stars
684
$25.91Chewy Price
($0.15/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Ease of use

4.2/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.4/5
Great

Long-lasting relief

4.3/5
Great

Is this dog itch relief & hot spot treatment right for my pet?

Breed Size

All Breeds

Lifestage

Adult, All Lifestages

Top Ingredients

Active Ingredients: Omega-3, Omega-6, EPA, DHA

Special Diet

Natural