Dorzolamide HCL (Generic) Ophthalmic Solution 2%, slide 1 of 1

Dorzolamide HCL (Generic) Ophthalmic Solution 2%, 10-mL

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Dorzolamide is used as a treatment for glaucoma, and is often prescribed by veterinarians for use with dogs and cats. This drug contains a carbonic anhydrase inhibitor which decreases intraocular pressure, a characteristic of many types of glaucoma.


Dorzolamide HCl Ophthalmic Solution is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Possible Side Effects

The most frequently reported adverse reactions associated with Dorzolamide HCl Ophthalmic Solution were ocular burning, stinging, or discomfort immediately following ocular administration (approximately one-third of patients). Approximately one-quarter of patients noted a bitter taste following administration. Superficial punctate keratitis occurred in 10 to 15% of patients and signs and symptoms of ocular allergic reaction in approximately 10%.

Drug & Food Interactions

There is a potential for an additive effect on the known systemic effects of carbonic anhydrase inhibition in patients receiving an oral carbonic anhydrase inhibitor and Dorzolamide HCl Ophthalmic Solution. The concomitant administration of Dorzolamide HCl Ophthalmic Solution and oral carbonic anhydrase inhibitors is not recommended.

Although acid-base and electrolyte disturbances were not reported in the clinical trials with Dorzolamide HCl Ophthalmic Solution, these disturbances have been reported with oral carbonic anhydrase inhibitors and have, in some instances, resulted in drug interactions (e.g., toxicity associatedwith high-dose salicylate therapy). Therefore, the potential for such drug interactions should be considered in patients receiving Dorzolamide HCl Ophthalmic Solution.


Dorzolamide HCl Ophthalmic Solution contains dorzolamide, a sulfonamide; and although administered topically, it is absorbed systemically. Therefore, the same types of adverse reactions that are attributable to sulfonamides may occur with topical administration of Dorzolamide HCl Ophthalmic Solution.

This drug is FDA-approved for human use. However, it is common practice for veterinarians to prescribe such drugs for use in dogs and cats.

NOTE: For Generic Medications, picture displayed may not depict actual product. Generic medications may vary from one order to the next by size, color and shape depending on manufacturer.

  1. Prescribing Information

See all items by Dorzolamide

  • Item Number
  • Generic Name
    Dorzolamide Hydrochloride
  • Common Brand Name(s)
  • For Use With
    Dogs & Cats
  • Administration Form
  • Product Form
  • Health Condition
  • Drug Type

Active Ingredients: Dorzolamide Hydrochloride Inactive Ingredients: Hydroxyethyl cellulose; mannitol; trisodium citratedlhydrate; sodium hydroxide; water; benzalko niumchloride.

Recommended Dosage

The dose is one drop of Dorzolamide HCl Ophthalmic Solution in the affected eye(s) three times daily. Dorzolamide HCl Ophthalmic Solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure.

Storage Instructions

Store at 68°F - 77°F. Protect from light.


What is Dorzolamide HCL?

Dorzolamide HCL can be prescribed by your veterinarian to assist in the reduction of pressure in the eye due to high blood pressure or glaucoma.

What to do if medicine is applied more than the recommended amount?

Flush the eye with water and call your veterinarian.

How should I store Dorzolamide HCL?

Store at room temperature and protect from light, moisture, and heat.

Rating: 4.5 of 5 stars 7 Reviews 7 Reviews 4.6 out of 5 Stars

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Rating: 4.5 of 5 stars 4.6 / 5

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  • 5 out of 5 stars

    These seem to work well

    By Johnfili on Nov 11, 2020

    My dog has glaucoma and was in pain from the eye pressure. These seem to relieve the pressure and ease her pain.

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  • 5 out of 5 stars

    Fast Delivery

    By Betty on Jul 24, 2020

    I was very pleased that I could get this prescription from Chewy. I was also pleased with the fast delivery. I will see if I can get Sophie’s other prescriptions through Chewy.

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  • 5 out of 5 stars

    Convenience and peace of mind

    By SonyaG on Apr 19, 2020

    I have a 3 pound yorkie rescue. He is around 6 years old. Along with a myriad of other health issues, he developed glaucoma in his left eye. We thought the eye might have to be removed. Fortunately, our wonderful vet tried medication first. These drops go in his right eye to hopefully prevent it from having glaucoma symptoms. Being able to rely on Chewy for his prescription food and now medicines has been a lifesaver. This little guy needs lots of help and love. Chewy is reliable and reasonably priced. Delivery is top notch.

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  • 5 out of 5 stars

    Best Price on a Necessary Perscription

    By Seniordogs on Feb 8, 2020

    My cocker has used this for years. She had to have one eye removed because we were unable to control the eye pressure so it is important for control of pressure in the remaining eye. I have gotten this product from several sources including my pharmacy for humans. The product is the same at all of the sources but Chewy is much less expensive when I have had to pay as much as twice as much at other places. Plus Chewy is dependable and pleasant to work with if there is a problem with any of my orders..lots of gold stars for customer service! Fortunately, we haven't had a problem with leaking.

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  • 5 out of 5 stars

    Awesome Awesome

    By Bella on Apr 25, 2020

    There are the best web-site for domestic animals needs and the cheapest!!!!!

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  • 5 out of 5 stars

    Wonderful drops

    By Janet on May 3, 2020

    Merchandise arrived on time. Wonderful customer service!

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  • 2 out of 5 stars

    Horrible Packaging

    By lindzg on Nov 14, 2019

    The product is great. BUT the last two I've purchased (mind you at a very high price) have leaked terribly. I literally feel like I'm wasting money. It oozes out the top and leaks!!!

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