Ketorolac Tromethamine (Generic) Ophthalmic Solution 0.5%, 10-mL bottle

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Keterolac is a non-steroidal anti-inflammatory drug (NSAID) used to treat swelling, also called inflammation, of the eye. While it’s FDA-approved only for use in humans, veterinarians are allowed to prescribe it to animals in certain situations. It should provide relief within one to two hours. It’s usually given two to four times a day. You and your veterinarian should discuss whether keterolac is appropriate for your pet and how you should administer it.


In veterinary patients, ketorolac is indicated for controlling anterior segment inflammation (eg, conjunctivitis, keratitis, anterior uveitis) and for providing analgesia following surgical removal of cataracts.

Possible Side Effects

Adverse effects reported in animals include transient stinging and burning on instillation, corneal edema, iritis, ocular inflammation, ocular irritation, superficial keratitis, and superficial ocular infections.

Drug & Food Interactions

Ketorolac is contraindicated in patients with a history of hypersensitivity to it or any component of the formulation. Potential for cross-sensitivity to acetylsalicylic acid, phenylacetic acid derivatives, and other NSAIDs exists. There have been reports of bronchospasm or exacerbation of asthma associated with the use of ketorolac tromethamine ophthalmic solution in patients that have either a known hypersensitivity to aspirin or NSAIDs, or a past medical history of asthma. Therefore, caution should be used when treating individuals that have previously exhibited sensitivities to these drugs.


Topical NSAIDs may result in corneal epithelial breakdown, and corneal thinning, erosion, or ulceration. Topical NSAIDs may slow or delay corneal wound healing.

  1. Prescribing Information

See all items by Ketorolac

  • Item Number
  • Generic Name
    Ketorolac Tromethamine
  • Common Brand Name(s)
    Acular, Acuvail
  • For Use With
  • Administration Form
  • Product Form
  • Health Condition
    Pain, Eye Infections
  • Drug Type
    Analgesic, Anti-inflammatory

Ophthalmic solution containing 5 mg/mL ketorolac tromethamine.

Recommended Dosage

Consult with your veterinarian on recommended dosage

Storage Instructions

Store at 68°F to 77°F


How is this medication useful?

Ketorolac is used to treat inflammation of the eye (eg, after cataract surgery). It is also used to treat itchy eyes caused by allergies. It works by inhibiting substances called prostaglandins that cause inflammation. The FDA (U.S. Food & Drug Administration) has approved this drug for use in humans but not in animals. The FDA allows veterinarians to prescribe products containing this drug in different species or for other conditions in certain situations. You and your veterinarian can discuss why this drug is the most appropriate choice.

How long until I will know if this medication is working, and how long will the effects of this medication last?

This medication should help your pet feel better within 1 to 2 hours. Your pet's clinical signs should improve after that time. The effects of this medication are moderate in duration, meaning they may last for a few days.

If my pet gets too much of this medication (an overdose), what should I do?

If you witness or suspect an overdose, contact your veterinarian or an animal poison control center for further advice. Animal poison control centers that are open 24 hours a day include: Pet Poison HELPLINE (855-764-7661) and ASPCA Animal Poison Control Center (888-426-4435); a consultation fee is charged for these services.

Rating: 5.0 of 5 stars 3 Reviews 3 Reviews 5 out of 5 Stars

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  • 5 out of 5 stars

    Prescription eyedrops

    By Windsor on Mar 30, 2021

    I had confidence in ordering the prescription from CHEWY. It wasn't the cheapest online however getting the correct pharmaceutical was most important.

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  • 5 out of 5 stars

    I was waiting for this product to be available thru Chewy

    By Barngirl on Jan 7, 2021

    When my pup was diagnosed with cataracts and PRA the Vet prescribed Ketorolac. It wasn't available at the time but I was curious about what the price would be. I can find it cheaper at a local pharmacy. The convenience of Chewy doesn't outweigh the cost for me. I'll keep looking back tho to see if it changes once it isn't considered a "new" product.

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  • 5 out of 5 stars

    Grateful for Chewy

    By Lizzy on Jan 6, 2021

    I’m so happy chewy had this! I tried to get this for my pup at a regular pharmacy and it cost 70 bucks, and they no longer offer discounts for pets. Thank goodness for Chewy!!!

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