Keterolac is a non-steroidal anti-inflammatory drug (NSAID) used to treat swelling, also called inflammation, of the eye. While it’s FDA-approved only for use in humans, veterinarians are allowed to prescribe it to animals in certain situations. It should provide relief within one to two hours. It’s usually given two to four times a day. You and your veterinarian should discuss whether keterolac is appropriate for your pet and how you should administer it.
In veterinary patients, ketorolac is indicated for controlling anterior segment inflammation (eg, conjunctivitis, keratitis, anterior uveitis) and for providing analgesia following surgical removal of cataracts.
Possible Side Effects
Adverse effects reported in animals include transient stinging and burning on instillation, corneal edema, iritis, ocular inflammation, ocular irritation, superficial keratitis, and superficial ocular infections.
Drug & Food Interactions
Ketorolac is contraindicated in patients with a history of hypersensitivity to it or any component of the formulation. Potential for cross-sensitivity to acetylsalicylic acid, phenylacetic acid derivatives, and other NSAIDs exists. There have been reports of bronchospasm or exacerbation of asthma associated with the use of ketorolac tromethamine ophthalmic solution in patients that have either a known hypersensitivity to aspirin or NSAIDs, or a past medical history of asthma. Therefore, caution should be used when treating individuals that have previously exhibited sensitivities to these drugs.
Topical NSAIDs may result in corneal epithelial breakdown, and corneal thinning, erosion, or ulceration. Topical NSAIDs may slow or delay corneal wound healing.
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