Out of Stock EnteDerm Topical Ointment for Dogs & Cats, slide 1 of 1

EnteDerm Topical Ointment for Dogs & Cats

Prescription Item

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Size: 7.5-mL
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EnteDerm is a topical ointment prescribed by veterinarians to help treat pets with bacterial infections or yeast infections found in the ears. This medication is gentle and readily accepted by most pets, relieving stress for you both.


This medication is particularly useful in the treatment of acute and chronic otitis of varied causes, in pets with lesions located on their paws, and in anal gland infections. The preparation is also indicated in the management of dermatologic disorders characterized by inflammation and dry or discharge dermatitis, particularly those caused, complicated or threatened by bacterial or candidal (Candida albicans) infections. It is also of value in other types of dermatitis and as an adjunct in the treatment of dermatitis due to parasitic infestation.

Possible Side Effects

Please contact your veterinarian if the following adverse reactions occur: excessive thirst/excessive dilute urine, vomiting, diarrhea (occasionally bloody) or hearing loss. However, regression of hearing usually occurred following withdrawal of the drug. If hearing dysfunction is noted during treatment, discontinue its use. Cushing’s syndrome has been reported in association with prolonged or repeated steroid therapy in dogs.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting this medication.


In case of allergic reaction, administer epinephrine. In case of human exposure, contact a physician. Do not use in pets who are allergic to the active ingredients in this medication. This is a topical medication—not to be given by mouth. Do not use if your pet’s ear drum is ruptured, if she has deep skin infections, is pregnant or lactating. Wear gloves if you are pregnant.

  1. Prescribing Information

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  • Item Number
  • Common Brand Name(s)
  • For Use With
    Dogs & Cats
  • Generic Name
    Nystatin, Neomycin Sulfate, Thiostrepton, Triamcinolone Acetonide Ointment
  • Administration Form
  • Brand
  • Product Form
  • Health Condition
    Skin Infections, Ear Infections, Atopic Dermatitis (Eczema)
  • Drug Type
    Antibiotic, Antifungal, Anti-inflammatory

Nystatin, Neomycin Sulfate, Thiostrepton and Triamcinolone Acetonide ointment.

Recommended Dosage

The frequency of administration is dependent on the severity of the condition. For mild inflammations, the application may range from once daily to once a week; for severe conditions, this medication may be applied as often as two to three times daily, if necessary. The frequency of treatment may be decreased as improvement occurs. Wear gloves during the administration of the ointment or wash hands immediately after application.

Storage Instructions

Do not store above 86°F. Other sizes, store at room temperature; avoid heat above 104°F.


What is EnteDerm?

This is an ointment that is applied to the skin or ears. It contains antibiotic, antifungal, and corticosteroid which helps to treat bacterial and yeast infections plus inflammation on the skin and in the ears.

What are the benefits of EnteDerm?

Used on the skin.

Very gentle and readily accepted by most pets.

Effective against fungal and bacterial infections in the ear and on the skin.

How is this medication given?

Always follow your veterinarian's exact instructions regarding the amount and frequency of use for EnteDerm.

Be sure to wash your hands before and after each application. Wear gloves if your pet has a contagious condition or if you are pregnant.

The hair around the skin lesion or ears may need to be clipped in order to ensure proper application. If your pet's ears are dirty, clean ears with a non-irritating ear cleanser and dry prior to instilling EnteDerm and massage ears to distribute medication evenly.

Call your veterinarian if you have questions about how to use EnteDerm correctly.

How does this medication work?

The combination of active ingredients work to treat bacterial (Thiostrepton/Neomycin) and yeast infections (Nystatin) on the skin and in the ear(s). Triamcinolone is a corticosteroid that reduces inflammation and helps your pet to feel better.

What results can I expect?

EnteDerm treats acute and chronic ear infections (otitis) as well as superficial skin infections, interdigital cysts, and anal gland infections. Your pet should feel better and symptoms should resolve when EnteDerm is used as directed.

Rating: 4.8 of 5 stars 37 Reviews 37 Reviews 4.9 out of 5 Stars

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97% Recommend

97% of reviewersrecommend this product

Rating: 4.8 of 5 stars 4.9 / 5

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37 Reviews

Showing 1-10 of 37 Reviews

  • 5 out of 5 stars

    Miracle med!

    By Chelsea on Jan 17, 2021

    My German Shephard is constantly licking an area until it is completely raw. I put a little bit of this stuff on each area and within a couple of days, it is much better and closer to healing. This is a great price for this product, compared to what I paid for the first bit from the vet! Highly reccomend!

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  • 5 out of 5 stars

    Economical medicine

    By Ears on Feb 4, 2021

    It is extremely helpful financially to be able to purchase medications for pets if on a budget or have multiple pets. Although the tubes are smaller and I had to purchase a minimum of 3; I received more doses and saved $4!! Thanks!

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  • 5 out of 5 stars

    Great price

    By Christinal on Mar 15, 2021

    The price is great. I needed a refill for my cats and even with shipping, this was 1/3 the price the vet's office charged.

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  • 5 out of 5 stars

    Magic Skin Ointment

    By Janet on Dec 4, 2020

    Entederm was the only thing that soothed the belly skin on my dog which had turned black from licking. He has an autoimmune disease that causes his skin to feel irritated and at one time he had lesions on his groin and around the edge of his lips. Entederm cleared the lesions and stopped him from licking his belly. After about a month of rubbing the ointment on his belly it began to turn pink again and hair grew back. My vet told me the skin would stay black. No true.

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  • 5 out of 5 stars

    Solves the problem

    By WildingsGuardian on Feb 24, 2021

    My cat has had several intermittent flare-ups in one of his ears. EnteDerm cures what ails and he doesn't mind the application! Life saver!

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  • 5 out of 5 stars

    Good product!

    By GoldenLove on Jan 11, 2021

    Im so happy that Chewy sell this product It's a very good product & I have plenty to use for quite awhile. Thanks Chewy!

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  • 5 out of 5 stars

    Results visible next day.

    By Twitterisfortwits on Oct 4, 2020

    My cat has had a fungal infection since July. The vet gave me some other brand which sort of worked. But in September, it suddenly erupted into a deep, open runny sore. By the time I got an appointment it was spreading rapidly. This time I got the good stuff (EnteDerm) and the sores shrank significantly overnight. The vet charged me over $18 for a 7ml tube! I need to get some from Chewy to make sure this problem is cured finally. I can't take much more of this.

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  • 5 out of 5 stars

    Ear and skin inflammations

    By Toots on Dec 1, 2020

    This was prescribed by our vet to treat our recent rescue, a French Bulldog, with severe skin and ear infections. Worked very well with a combo of oral medications.

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  • 5 out of 5 stars

    Entederm is my vet's choice for my dog's ear infections.

    By Mooke on Jan 18, 2021

    Vet recommended Entederm for my dog's ear infections and it works after applying it for 10 days .

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  • 4 out of 5 stars

    Slow at first

    By Feli on Dec 7, 2020

    the process was slow but once the ear medicine arrived I was happy because my puppers would finally be out of pain

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