Nature's Miracle Cat Urine Destroyer Plus Enzymatic Formula Stain Remover, 32-fl oz bottle

Skip image gallery
Slide 1 of 11

$8.27 First Time Autoship Price
this order
Save 35% today when you set up Autoship. 
$12.08 Autoship Price
(-5%) future orders
  • Keep saving 5% on every order
  • Get deliveries on your schedule
  • Skip, change, or cancel anytime
$12.72 Chewy Price
($0.40 /fl oz)
Save $2.27 (-15%)
$14.99 List Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME
Promo, Buy select item, get free Earth Rated potty pad with code ERPADFREE
In Stock
FREE 1-3 day delivery on first-time orders over $35
Free 365-day returns

No interest if paid in full in 6 months on PayPal purchases of $149+. .

About This Item

At a Glance

  • Made in USA
  • All Lifestages

Details

  • Works to break down and remove cat urine stains on contact.
  • Easy to use—simply soak the affected area, allow to work for 15 minutes, then blot with a clean cloth.
  • The enzymatic formula keeps working as long as any bio-based mess is present.
  • Nature’s Miracle bottles are designed with 25% post-consumer recycled material.
  • Safe for use around your pets and home when used and stored as directed.

Instructions

Learn More About Nature's Miracle From Our Team of Experts

About Nature's Miracle Stain and Odor Solutions

Trust the Miracle

Nature’s Miracle pet stain and odor removers have been a trusted choice for pet mess cleanup for over 40 years. When your pets make not-so-cute messes, you can always rely on Nature’s Miracle products to get the job done.

Solutions for the Toughest Pet Messes

Nature’s Miracle stain and odor formulas help you tackle tough pet messes like urine, feces, vomit and drool. From spot-cleaning everyday messes to eliminating stubborn stains, these solutions help you keep your home clean.

Break Down Stains on Contact

Nature’s Miracle cleaning formulas start to work the moment they come in contact with pet messes. With several targeted cleanup solutions available, you’ll find it easy to choose just the right product for your needs.

Not All Pet Messes Are the Same

Solutions for Dogs

Nature’s Miracle products for dogs are specially formulated to handle your dog’s messes. Choose from a variety of formulas tailor made to handle any canine stain or odor removal jobs that come your way.

Solutions for Cats

Cat messes and odors present their own unique challenges, and Nature’s Miracle products for cats are specially formulated to tackle them. From Urine Destroyer to enzymatic Stain & Odor Remover formulas, these products are made to get the job done.

Targeted Solutions for Life With Pets

Original Stain & Odor

The original, must-have formula made for cleaning up everyday pet messes.

Simply Nature’s Miracle

Made with 86% plant-based surfactants and essential oils for fragrance, you can feel good about using these in your home.

Urine Destroyer

These targeted formulas are made to destroy severe urine stains and odors and get rid of yellow, sticky residue.

Advanced Eliminators

Use these advanced bio-enzymatic and antibacterial formulas to eliminate the most severe pet messes.

Sprays and Gallon Sizes

Choose from a range of convenient sprays to have on hand for targeted cleanup on a variety of surfaces. The easy-to-store gallon jugs are great for refills and perfect for multi-pet homes, too.

Easy Pour

Get the right amount of solution right where you need it with this easy-pour bottle and spout.

Aerosol Foam

Penetrating aerosol foam gets deep down into carpet fibers to power out severe pet messes.

About Nature's Miracle

Cat messes and odors present their own unique challenges, and Nature’s Miracle litter box products for cats are specially formulated to tackle them. Make life with your cat a little more pleasant with these trusted litter box solutions!

Shop Nature's Miracle

Frequently bought together

Questions & Answers

25 Customer Questions

Can this be used with a bissel upright cleaner

Answer by HRHFishAreFish • Dec 30, 2023
I've done it several times, but I watered it down quite a bit in the reservoir (more water than miracle!). I also rinse steam cleaned the carpet with plain water afterwards. Full strength and I think the fresh scent would be overwhelming. Works great for apartment turnovers with cat odors and on other difficult odors as well, such as carrion.

Is this tested on animals

Answer by Chewy • May 20, 2020
Natures Miracle Cat Enzymatic Urine Destroyer is not certified as cruelty-free.

Can you use this to mop an entire floor safely? Does it need to be diluted?

Answer by Chewy • Jul 07, 2022
You’ll want to mop up any excess mess first. Then mop the floor with product full-strength. Do not dilute.

Can you spray this on blankets or clothing And then wash in the washing machine

Answer by Chewy • Sep 10, 2019
It is recommended to use the Nature's Miracle Laundry Boost in your washing machine. Other formula's, like the Urine Destroyer, can be used for pre-treating clothes. Just be sure to do a color-fastness tests on anything your washing before use.
Reviews
Write a Review
4.4
Rated 4.4 out of 5 stars
1107 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

87% Positive

Effectiveness

84% Positive

Safety

81% Positive

Stain Type

80% Positive

392 Customer Reviews

Rated 1 out of 5 stars
By J on Jan 30, 2026

Extremely Toxic

This gives me a severe toxic headache from the overpowering smell within minutes of spraying. This cannot be healthy for small animals to breathe. I am truly shocked

This gives me a severe toxic headache from the overpowering smell within minutes of spraying. This cannot be healthy for small animals to breathe. I am truly shocked at the 5 star reviews. Even with a fan on it’s terrible. Do not buy this product for health reasons and I’m pretty sure the headache is from the toxins crossing the brain barrier.

Rated 4 out of 5 stars
By CATHERINE on Jan 28, 2026

Worked well

Tessa peed in her carrier on the way to her vet appointment, and it soaked the fabric seat of my car. This product almost took the odor away. It was fine in the

Tessa peed in her carrier on the way to her vet appointment, and it soaked the fabric seat of my car. This product almost took the odor away. It was fine in the winter, but when the car was closed up in the summer the smell was detectable. This 2nd winter we've been able to use the seat warmer with no problem.

Rated 5 out of 5 stars
By Lilith on Dec 18, 2025

For URINE even better than the RED bottle!

I've used Nature's miracle products for years for my cats. Always found that the RED bottle of the Advanced enzymatic cleaner *just for cats* is the best cleaner

I've used Nature's miracle products for years for my cats. Always found that the RED bottle of the Advanced enzymatic cleaner *just for cats* is the best cleaner in the universe. It was able to remove the stain of an entire glass of red wine spilled on a white couch (ask me how I know). However, my youngest male cat developed FLUTD and has been spraying all over the house. He especially likes to mark window treatments and rugs that cannot be removed or washed, but only spot cleaned. I've tried everything, and yes he's fixed. My trusted red bottle didn't fully remove the odor, and it felt like it was covering the urine marks rather than cleaning them. Male cat spraying is far more pungent than regular pee. On a whim, I decided to try this Nature's Miracle Urine Destroyer plus for cats and OMG what a game changer! I need to use a lot less of this compared to the red bottle to feel like the marked spots are getting clean. And as promised, it gets rid of that sticky residue that the other bottle can't quite eliminate. The scent of this one is also way more pleasant. Before I used to feel like I traded the pee stink for that strong Nature's Miracle smell. Not the case with this one. It smells lightly floral like fresh laundry. For all other kinds of messes, from vomit and blood to red wine on white couches, I still think the Red bottle (aka advanced enzymatic for cats) is the most effective. But to remove urine stains and odors from fabrics, such as rugs, pillows, and curtains, this one takes the crown.

Rated 5 out of 5 stars
By Charlene on Jan 23, 2026

It works

The new kids have had litter box issues that are finally getting better, but there’s still accidents that need to be cleaned up, and this eliminates the urine smell

The new kids have had litter box issues that are finally getting better, but there’s still accidents that need to be cleaned up, and this eliminates the urine smell from the floor and also cleans. Figured the gallon bottle would save me money over getting the spray bottle each time.

Rated 5 out of 5 stars
By MEGHAN on Jan 20, 2026

It works!

This is the only product I have used that actually kills the smell. Follow directions and wow! It does not deter my cat from returning to the carpet spot, but helps

This is the only product I have used that actually kills the smell. Follow directions and wow! It does not deter my cat from returning to the carpet spot, but helps in the ongoing battle of wills.

Rated 5 out of 5 stars
By Cliff on Dec 16, 2025

Excellent stuff

It works. I haven't needed it in years, but I've got kittens again, so I need to clean up messes. This stuff is the most ut, as Judy Jetson said. No stains on the

It works. I haven't needed it in years, but I've got kittens again, so I need to clean up messes. This stuff is the most ut, as Judy Jetson said. No stains on the carpet.

Rated 3 out of 5 stars
By CatLady48 on Oct 20, 2025

Smells good

I think that it works better than most enzymatic cleaners, but unfortunately my cats continued to spray areas that I have used this in. It smells good though and

I think that it works better than most enzymatic cleaners, but unfortunately my cats continued to spray areas that I have used this in. It smells good though and seems like it really cleans the area because with a black light I do not see the pee smudges anymore. Doesn't work as well in fabric though. It stills smells like pee so I had to throw some things away.

Rated 5 out of 5 stars
By Elizabeth on Sep 29, 2025

Marked spot!

Urine on previously marked spot by other cat. There’s a part of my carpet in the corner where a previous cat urinated on it. Recently one of my boys smelled it and

Urine on previously marked spot by other cat. There’s a part of my carpet in the corner where a previous cat urinated on it. Recently one of my boys smelled it and felt the need to also urinate in it. While yes, the spot was previously cleaned however for some reason, my current cat still smelled it and peed in the area. I spray this in the same area after cleaning the carpet again and my cat hasn’t urinated in the area again.

Rated 5 out of 5 stars
By Petmom7 on Oct 4, 2025

Great product!

I have 5 cats and one of my males tends to mark the walls when he is upset. This product has been fantastic. I have pine wood walls in my family room area so that

I have 5 cats and one of my males tends to mark the walls when he is upset. This product has been fantastic. I have pine wood walls in my family room area so that absorbs the urine and this actually takes all the urine smell away and it is fresh and clean after. Also use if one of the kitties gets a bit of urine outside the box. I highly recommend this product,

Rated 1 out of 5 stars
By Sarah on Nov 10, 2025

Not good

Doesn’t work at all. Made our cat spray more after we sprayed. And the smell makes you want to gag-way better smelling with the cat spray but not much better. To

Doesn’t work at all. Made our cat spray more after we sprayed. And the smell makes you want to gag-way better smelling with the cat spray but not much better. To potent and doesn’t work at all.