Sentinel Spectrum Chew for Dogs, 25.1-50 lbs, (Yellow Box)

Sentinel Spectrum is indicated for the prevention of heartworm disease. It is also formulated to help prevent and control flea populations, and for the treatment and control of adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies six weeks of age and older and weighing at least two pounds.

The following adverse reactions have been reported in dogs after administration of milbemycin oxime, lufenuron, or praziquantel: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, salivation, and weakness.

There are no known contraindications to the use of Sentinel Spectrum.

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Sentinel Spectrum, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. This medication is not effective against adult D. immitis. Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Do not use in puppies less than six weeks of age. Do not use in dogs or puppies less than two pounds of body weight. The safety of this medication has not been evaluated in dogs used for breeding or in lactating females. Studies have been performed with milbemycin oxime and lufenuron alone. Not for use in humans. Keep this and all drugs out of the reach of children.