URSODIOL (Generic) Tablets, 250-mg, 30 tablets - Chewy.com

Ursodiol (Generic) Tablets, 250-mg

By Ursodiol
Rated 4.3636 out of 5 stars
Prescription Item

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$41.10Chewy Price
$39.04Autoship Price
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About This Item


Ursodiol is a prescription medication given to treat certain diseases of the liver and gallbladder, including chronic hepatitis. It may also be used to help remove gallstones that contain cholesterol. It is an uncoated tablets and customers may receive this drug under the names Actigall, Urso.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Play Video: Learn More About Ursodiol From Our Team of Experts
Learn More About Ursodiol From Our Team of Experts

ReviewsWrite a Review

Rated 4.3636 out of 5 stars
11 Ratings
Would recommend to a friend

11 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Bobb on Apr 21, 2023

Not bitter

This medicine has been prescribed for life. I was worried that the pill would be bitter and I was going to be fighting with our dog. That’s not the case. I sandwich her pill with soft/loaf type food and the dog is fine with that. I heard of another method. Put pill in a little marshmallow. I thought this would be my back up plan. Our side effects are non issue.

Rated 5 out of 5 stars
By bb625 on Apr 24, 2023

Must have!

This medication is great for dogs with liver and/or gallbladder issues. We have used it on several of the older rescue dogs and it has lowered liver values which improves appetite and quality of life. Must have for any dog with elevated liver enzymes!

Rated 4 out of 5 stars
By Anais on Jul 26, 2022

Causes stomach pain but works to lower ALT

Causes dog stomach pain, terror at night about 5-6 hours after ingestion. Licks the air, comes closer to me than usual to let me know he's hurting and scared. But it does keep the ALT lower over time. Must be given with food - so he eats lunch, 20 minutes later I give the pill, and within 30 minutes to an hour I feed him again to decrease pain and upset stomach. Moved it to noon instead of dinner meal so he sleeps better at night. Giving full meal before and a second meal right after seems to help.

Rated 3 out of 5 stars
By Tutset on Jun 20, 2022

Autoship dropped the ball

This last cycle I added the ursadiol into my regular autoship order and moved up the shipment date to immediately, but the pharmacy totally dropped the electronic request. Five (working) days later, I called to find out what is up, and they hadn’t even started working in it. And I had moved the ursadiol to the Chewy pharmacy because you guys are “so efficient”! Frustrating - between that and obtaining my vet’s confirmation on ursodiol, my pet was off the med for two weeks.

Rated 5 out of 5 stars
By Woofie on May 2, 2022

To all the people asking for a smaller dosage... stop.

Hi friends, first thank you to Chewy for having fair prices and fast delivery! 2nd to everyone asking for a smaller dosage please don't. Typically pet meds are sold by the pill. A 125mg pill would cost about the same as a 250mg for half the product, hence more expensive overall. Furthermore, vets would have to prescribe only the correct dosage. If the manufacturer does start making smaller dosages then prices will increase approximately 80% again for the same quantity of the product. I find it helpful to take kitchen shears and cut it half in the dog bowl that way no product is wasted. It takes all of 30 seconds.

Rated 3 out of 5 stars
By RileysMom on Feb 17, 2022

dosage splitting

My dog's prescription is for half of a 250mg table twice a day which apparently is a very common dosage for dogs. So why not have 125mg tablets, or at the very least, tablets that are scored for easier splitting? I have to cut them in half with a chef's knife. For the cost of these tablets, the manufacturer should definitely produce them scored for easier splitting. We love the convenience and quick response time of Chewy Pharmacy:-)

Rated 5 out of 5 stars
By Tangogirl1 on Dec 19, 2021

Quantity Available

Looks like the ability to select a specific quantity was removed to options: 1 tab; 30 tabs; 60 tabs. I split my tab in quarters and try to time the auto-ship with other items. 30 tabs would be 4 month supply, however, i would prefer to order along with my monthly order, which is not possible. Chewy, please consider going back to being able to order a specific quantity.

Rated 5 out of 5 stars
By CuppyArgos on Nov 15, 2021

Great price, and effective!

My pup was prescribed for her gallbladder and liver. It seems to be working. The vet’s price was 3x Chewy’s price. So I order here! Quick delivery, and easy pill to hide in food.

Rated 3 out of 5 stars
By Krista on May 22, 2021

change in brand?

This is the third time I’ve had this prescription filled by Chewy and I have to assume either they started giving out a different brand or the original brand making the medication changed the pill. Splitting them this time was a nightmare. I had to toss several pills because they didn’t split nearly well enough to just give it to her anyway. There is a coating type thing on the pill now that either flaked off or hung on(as seen in the picture). I have to assume the main reason for the problems with splitting were because the pill is more rounded now and wasn’t staying in the splitter very well at all or for whatever reason just became harder to split in general, plus it has some weird coating on the pill that wasn’t previously there(at least not like this). I love Chewy and I love their pharmacy and I really hope the next time I need this filled, this isn’t an issue. I’m not sure I’d get it filled again here if the same thing happens. I’d pay more for another place to make sure the dosage is split correctly by either myself or the pharmacy. Please either change the pill back to the previous brand or add the service of splitting pills for people.

Rated 5 out of 5 stars
By MyronnABQ on Sep 19, 2020

Competitive price, easy to portion

Your pet is likely prescribed less than 250mg of Ursodiol per dose. Unlike some other brands of Ursodiol, these pills are easy to cut and do not crumble during the process.