Zymox Otic Dog & Cat Ear Infection Treatment without Hydrocortisone, 4-fl oz bottle

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About This Item

At a Glance

  • All Lifestages
  • All Breeds

Details

  • Great for dogs and cats of all ages.
  • The gentle, no-sting formula works to soothe ear infections, redness and inflammation.
  • Paw-fect for sensitive pets, this solution contains no antibiotics or hydrocortisone.
  • No pre-cleaning of painful ears required—simply fill the ear canal and let this antimicrobial solution get to work.
  • Helps clear ear secretions and promotes healthy ears.

Ingredients

Instructions

Learn More About Zymox From Our Team of Experts

About ZYMOX Enzymes for Healthy Ears and Skin

Antimicrobial and Antifungal Care

ZYMOX empowers pet parents with patented formulations of natural enzymes to help treat chronic infections in dogs, cats and horses. Their products are formulated to be safe to use on any age pet. ZYMOX packs a potent antimicrobial punch that targets the source of infections—bacteria and fungus(including yeast) to provide therapeutic relief, care, protection and prevention, without any antibiotics or harsh chemicals. Proudly made in the USA and endorsed by TICA (The International Cat Association).

Committed to Healthy Ears, Skin and Coat, and Smiles

To ensure overall health from snout to tail on all four-legged pals, Zymox has developed products that are specially formulated for all the areas that commonly need infection relief, like the ears, teeth and gums, and skin and coat.

Ear Care Solutions

Effective, non-toxic solutions with special enzymes and mild cleansers to keep ears clean and fresh, and combat microbes that can cause ear infections.

Oral Care Solutions

Brushless solutions with unique enzymes to dissolve plaque and prevent its buildup, boost natural "good bacteria," and protect against gum disease to keep kitty and doggy smiles healthy.

Skin and Coat Health

Topical sprays and shampoos for dogs, cats and horses that form a powerful protective barrier against minor skin inflammations from bacteria and fungi, while cleaning and conditioning the coat—with some formulas utilizing hydrocortisone.

100% Safe, Gentle and Easy

Because Zymox formulas are made with 100% naturally derived enzymes from dairy, they are safe for anytime use, both for immediate soothing relief and to prevent infections. The powerful enzymes work to eliminate problem single-celled organisms such as bacteria, fungi and yeast, while leaving healthy cells untouched. This means no irritations for your pal!

Enzyme-Based and Antibiotic-Free

Zymox products use a patented, gentle formulation that combines three potent, naturally occurring enzymes—lactoperoxidase, lysozyme and lactoferrin—that are sourced from milk products. These enzymes are proven to work together to eliminate the source of infection on your pet, without any toxins or antibiotics that can irritate or cause antibiotic resistance.

About ZYMOX

Zymox was founded in 1998 by Pamela Bosco, who sought to change the way that people treated and managed ear, oral and skin infections with a safer alternative to antibiotics. Enlisting the help of her brother—a scientist that developed the enzyme technology in Biotene—Bosco formulated a powerful enzyme-based solution to help treat infections in dogs, cats and horses with no toxins, chemicals or antibiotics. Committed to keeping all four-legged pals healthy, they offer USA-made and sourced products to treat, soothe and protect against bacterial and fungal infections gently and 100% naturally.
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Frequently bought together

Questions & Answers

16 Customer Questions

Can zymox be used for ear wax buildup

Answer by Chewy • Aug 02, 2021
The powerful enzymatic action of the patented LP3 Enzyme System naturally cleans, disinfects and removes ear exudate while destroying even the most resistant microbes.

Can this be used for other animals like rabbits ???

Answer by Chewy • May 30, 2019
ZYMOX® is formulated without antibiotics, harsh chemicals and is non-toxic. It is ideal for dogs, cats and can be used on furry pets and farm friends of all ages.

Do I need a prescription for this?

Answer by Chewy • Dec 17, 2018
This does not require a prescription.

Is this product considered a good treatment for inner ear infections in cats?

Answer by Chewy • Dec 03, 2023
This infection treatment is perfect for treating the inner ears.
Reviews
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4.5
Rated 4.5 out of 5 stars
424 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Durability

77% Positive

Ease of Use

86% Positive

Effectiveness

86% Positive

Safety

83% Positive

300 Customer Reviews

Rated 5 out of 5 stars
By Linda on Dec 27, 2025

Zymox is amazing!

The smell, nasty, dirty, black ear stuff, and itch were amazingly gone in a couple days. Been using it for a week now. What a difference.

The smell, nasty, dirty, black ear stuff, and itch were amazingly gone in a couple days. Been using it for a week now. What a difference.

Rated 5 out of 5 stars
By Kimberly on Sep 7, 2025

Been using this for years And have never had an ear issue

This is the holy grail for ear health. Thanks to a review a decade ago, I clean my dog’s ears weekly with this and she has long hair too and has never had an ear

This is the holy grail for ear health. Thanks to a review a decade ago, I clean my dog’s ears weekly with this and she has long hair too and has never had an ear issue. Never an infection or fungal issue.. if I miss a week, sometimes it starts to change but I just clean her ears with this and they’re back to perfect health within a few days

Rated 5 out of 5 stars
By Annette on Jul 27, 2025

Worked Great

Our Great Dane gets pretty frequent ear infections. We usually have to take her to the vet to get her ears packed but that cost can add up quickly. I was hoping

Our Great Dane gets pretty frequent ear infections. We usually have to take her to the vet to get her ears packed but that cost can add up quickly. I was hoping to try something we can do at home and see if it worked and after researching I tried this. I have to say it knocked out the infection and her ears look amazing, I plan on continuing to use this a preventative and the cost is great. I definitely recommend trying it

Rated 4 out of 5 stars
By Katherine on Sep 24, 2025

Works well to prevent ear infections

My vet recommended using this twice a week to prevent ear infections. As long as I use regularly, she no longer gets. It works great. Expensive but cheaper then

My vet recommended using this twice a week to prevent ear infections. As long as I use regularly, she no longer gets. It works great. Expensive but cheaper then I can get at vet

Rated 5 out of 5 stars
By Kitty on Nov 11, 2025

It worked

Captain did have to go to the doctor's ultimately - but this tool will help him stay yeast free!

Captain did have to go to the doctor's ultimately - but this tool will help him stay yeast free!

Rated 5 out of 5 stars
By Faith on Sep 6, 2025

It works

I have two dogs that constantly get yeast and bacterial ear infections. I use Zymox in their ears every Sunday and they have never had an ear infection again.

I have two dogs that constantly get yeast and bacterial ear infections. I use Zymox in their ears every Sunday and they have never had an ear infection again.

Rated 5 out of 5 stars
By Michelle on Oct 21, 2025

These were easy to use

When I used a cotton ball I had a difficult time getting it out. These wipes were easy and worked.

When I used a cotton ball I had a difficult time getting it out. These wipes were easy and worked.

Rated 5 out of 5 stars
By kathy on Oct 10, 2025

It works

Penny’s ear was really inflamed and this instantly calmed and healed. Followed directions.. very pleased!

Penny’s ear was really inflamed and this instantly calmed and healed. Followed directions.. very pleased!

Rated 4 out of 5 stars
By Kathy on Nov 2, 2025

Arrived promptly.

All the products were in good shape, but the delivery box was partially squashed!

All the products were in good shape, but the delivery box was partially squashed!

Rated 5 out of 5 stars
By Bill on Jul 1, 2025

It works!

I have two Scottish Terriers with a persistent yeast infection in one ear. It was manageable during cool weather but the summer temperatures aggravated it. After

I have two Scottish Terriers with a persistent yeast infection in one ear. It was manageable during cool weather but the summer temperatures aggravated it. After only 2 treatments ZYMOX cleared it up and it doesn't appear to be coming back. I wish I had found it sooner.