Treat those stubborn ear infections with the enzymatic power of the Zymox Plus Advanced Formula Otic Dog & Cat Ear Solution. Enzymes are naturally occurring proteins that are highly effective against bacterial, fungal and yeast ear infections, so it’s an excellent alternative to antibiotics. Working to destroy the offending organisms, this solution combines the increased potency of the proven antimicrobial LP3 Enzyme System with an additional four biofilm-reducing enzymes. These added enzymes actually penetrate the layer of slime often found in the ear, so ear infections don’t stand a chance. No cleaning of the ear is required so as not to disrupt the enzyme activity, and it’s even safe enough for nursing pets and sensitive exotics.
Naturally occurring enzymes are highly effective against bacterial, fungal and yeast ear infections. Great alternative to antibiotics and the non-toxic solution won’t irritate a pet’s sensitive or irritated skin. Safe enough for nursing/lactating pets and sensitive exotics.
Proven antimicrobial LP3 Enzyme System inhibits, splits and destroys the offending organisms while leaving healthy cells alone.
Four additional biofilm-reducing enzymes destroy the hard-to-penetrate biofilm slime layer that obscures the microbe.
Ideal for cases of repeated infections or infections that won’t resolve, and bacteria will never develop a resistance to the enzymes.
Made in the USA.
Important: Do not clean ears before or during use. Do not use in conjunction with topical ear products or cleaners. Do not allow water in or near ear during use. If condition persists or worsens, discontinue use and consult your veterinarian. Store at room temperature.
Warning: Do not use on punctured ear drums. Keep out of reach of children.
Shake well before use. Apply liberally to un-cleaned ear, filling ear canal. Gently massage and work into infected area. Wipe to remove excess. Allow animal to shake head. Use 1 time daily for 5 to 14 days. Safe for extended use on persistent cases.
Powerful Antimicrobial and Antifungal Care
ZYMOX empowers pet parents with patented formulations of natural enzymes to help treat chronic infections in dogs, cats and horses. Their products are also formulated to be safe to use on kittens, puppies and even senior dogs. These solutions pack a potent antiseptic punch that targets the source of infections—bacteria, fungi and yeasts—to provide therapeutic relief, care, protection and prevention, without any antibiotics or harsh chemicals.
Committed to Healthy Ears, Skin and Coat, and Smiles
To ensure overall health from snout to tail on all four-legged pals, Zymox has developed products that are specially formulated for all the areas that commonly need infection relief, like the ears, teeth and gums, and skin and coat. To keep furry ones happy, their products treat ear infections, skin allergies, hot spots, bad breath, gum disease and more.
Ear Care Solutions: Effective, non-toxic solutions with special enzymes and mild cleansers to keep ears clean and fresh, and combat microbes that can cause ear infections.
Oral Care Solutions: Brushless solutions with unique enzymes to dissolve plaque and prevent its buildup, boost natural "good bacteria," and protect against gum disease to keep kitty and doggy smiles healthy.
Skin and Coat Health: Topical sprays and shampoos for dogs, cats and horses that form a powerful protective barrier against minor skin inflammations from bacteria and fungi, while cleaning and conditioning the coat—with some formulas utilizing hydrocortisone.
100% Safe, Gentle and Easy
Because Zymox formulas are made with 100% naturally derived enzymes from dairy, they are safe for anytime use, both for immediate soothing relief and to prevent infections. The powerful enzymes work to eliminate problem single-celled organisms such as bacteria, fungi and yeast, while leaving healthy cells untouched. This means no irritations for your pal!
Enzyme-Based and Antibiotic-Free
Zymox products use a patented, gentle formulation that combines three potent, naturally occurring enzymes—lactoperoxidase, lysozyme and lactoferrin—that are sourced from milk products. These enzymes are proven to work together to eliminate the source of infection on your pet, without any toxins or antibiotics that can irritate or cause antibiotic resistance.
Zymox was founded in 1998 by Pamela Bosco, who sought to change the way that people treated and managed ear, oral and skin infections with a safer alternative to antibiotics. Enlisting the help of her brother—a scientist that developed the enzyme technology in Biotene—Bosco formulated a powerful enzyme-based solution to help treat infections in dogs, cats and horses with no toxins, chemicals or antibiotics. Committed to keeping all four-legged pals healthy, they offer USA-made and sourced products to treat, soothe and protect against bacterial and fungal infections gently and 100% naturally.
I bought this since it didn't have the hydrocortisone in it and thought I'd use one drop per day as a preventative in my Cockapoos ears. After a week of usage, he still got an ear infection. I will go back to using our other Zymox formula.
on Feb 8, 2021
My baby has had terrible issues with her ears this winter. After two expensive vet visits and 2 rounds of antibiotics, I decided to try on my own. I purchased this Zymox Plus. It had great reviews. It has really made her ears better. It has been 6 days and her ears are almost clear.
Review of product
on Feb 25, 2021
This product did not work for my dog. I will try other products for my dogs ears. He has alot of problems with yeast infections now that he is getting older.
It worked well for me
on Dec 11, 2020
Have a couple of my cats that have had ear issues for a while. I had tried several other remedies. The Zymox formula worked well.
on Oct 29, 2020
I absolutely love everything from chewy...but this product doesn't cut it. It's my fault I always order the red label and ordered the yellow to see how it works. My dog got 0 relief.
on Sep 8, 2020
I rarely write reviews but this works! Our poor elderly dog had what was diagnosed as an ear infection. Antibiotics, steroids, ear cleanser, nothing gave her relief. I saw this on Chewy and decided to try it. One treatment was it all it took to give her some relief. We continued it once a day for 7 days and ears are no longer bothering her.
Love these products!
on Aug 10, 2020
I have a lab & a dachshund who both have ear problems. The regular formula has worked well for us in the past but I decided to try the advanced formula this last time since the infection reoccurred a week after treatment. And boy did it make a difference! My dog didn’t have much visible ear discharge it was more redness, itching, & discomfort. On day 3 of the advanced formula i was surprised to see discharge! Never saw that kind of response from the other formula. I actually thought he had rubbed his ear on the ground at first but nope. It continued to loosen gunk from deep in his ears for several days. I did a 14 day treatment & we haven’t had an issue since!
on Oct 27, 2020
Day 5 slowly working his ear was bad alot of wax coming out I'd buy it again. Not itching or pulling so bad
on Sep 7, 2020
Order was received quickly - much appreciated since my dog has a regular need for protecting against ear infections. This works really well.
on Oct 14, 2020
Used this on my dogs that had gooky, smelly ears for a week. Cleaned them right up