Zymox Plus Advanced Formula 1% Hydrocortisone Otic Dog & Cat Ear Infection Solution, 1.25-oz bottle

By Zymox
Rated 4.8328 out of 5 stars
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About This Item

  • Naturally occurring enzymes are highly effective against bacterial, fungal and yeast ear infections, plus the anti-inflammatory power of hydrocortisone. While this formula isn’t designed to treat dog and cat ear mites, it could help relieve symptoms and protect against secondary infections from yeast, bacteria, and fungus.
  • Proven antimicrobial LP3 Enzyme System inhibits, splits and destroys the offending organisms while leaving healthy cells alone.
  • Four additional biofilm-reducing enzymes destroy the hard-to-penetrate biofilm slime layer that obscures the microbe.
  • Ideal for cases of repeated infections or infections that won’t resolve, and bacteria will never develop a resistance to the enzymes. Great alternative to antibiotics and the non-toxic solution won’t irritate a pet’s sensitive or irritated skin and is great for dogs and cats.
  • Made in the USA.
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Top IngredientsActive Ingredient: Hydrocortisone 1.0%., Inactive Ingredients: Benzyl Alcohol, Bet-Glucanase...Benzyl Alcohol, Beta-Glucanase, Cellulase...Active Ingredients: Hydrocortisone 1%., Inactive Ingredients: Benzyl Alcohol, Dextrose...Natural Enzymes, Lysozyme, Lactoferrin, Lactoperoxidase.
Health FeatureEar CareEar CareEar CareEar CareEar Care
LifestageAdultAdultAdultAdultAdult
Breed SizeSmall Breeds, Medium Breeds, Large Breeds

Questions & Answers

39 Customer Questions


What is the difference from the pluse and the regular version?
Answer by ChewyJun 23, 2017
The Zymox Plus Advanced Formula includes the same LP3 Enzyme System that's in the original Zymox Otic Pet Ear Treatment with Hydrocortisone, plus four additional biofilm-reducing enzymes that help penetrate the layer of slime often found in the ears that protect some microbes.

Will this take care of a ear yeast infection quickly and numb the ear? My yorkie has a reaccuring ear infection and her ear is swollen and crusty. She shakes her head and scratches.
Answer by ChewyJul 15, 2017
This product contains naturally occurring enzymes that are highly effective against bacterial, fungal and yeast ear infections, plus the anti-inflammatory power of hydrocortisone. We do encourage pet parents to consult with the veterinarian first to make sure there isn't an underlying medical issue.

Do I need a vet prescription?
Answer by ChewyOct 02, 2017
This product doesn't require a prescription.

What is the difference between this one and the zymax inflammation relief with 0.5% hydrocortisone? Is This one exactly the same except double strength?
Answer by ChewyJul 15, 2017
This formula has a higher percentage of Hydrocortisone, and it has a few differences in its inactive ingredients.


ReviewsWrite a Review

4.8
Rated 4.8328 out of 5 stars
658 Reviews
98%
Would recommend to a friend
1
1.6717
2%
2
1.2158
1%
3
1.0638
1%
4
4.2553
4%
5
91.7933
92%

658 Customer Reviews



Rated 5 out of 5 stars
By Kimm on Sep 30, 2022

Love this product

I waited till I finished the bottle before I would write this review. My Riley keeps getting ear infections- fungal infection which is a hard kind to get under control. When she got another infection in less than four months. I called the vet- who informed me that it would be over a week before they would see us I decided to try this product. So glad I did. My dogs ears look so much better. I am happy when my baby is feeling better


Rated 1 out of 5 stars
By Eileen on Sep 10, 2022

don't waste your money

I used this for my cat's ears and it did NOTHING. I wish I had learned about using coconut oil sooner, my poor cats' ears were itching so badly, he was bleeding from scratching so much. In 2 days, a little organic coconut oil on a q-tip swabbed inside the ear cleared up everything. It's safe, cheaper and more effective than this stuff. I feel guilty I dragged out the poor kitty's suffering and discomfort by not researching about coconut oil sooner.


Rated 4 out of 5 stars
By Johnny on Aug 21, 2022

Watered down version of the previous formula...

It still works, but it takes more applications, over about a full week, to show any meaningful results. They changed the instructions to allow it to be used EVERY DAY instead of a couple times a week. I don't know if it's just a weaker formula, or if they would like to sell us $40 bottles of this medicine more often, probably the latter. My beagle gets yeast infections in his ears couple times a year, so this medicine is a lifesaver. But it definitely seems to take more applications now, as I said. Something to keep in mind.


Rated 5 out of 5 stars
By Rottweilergrandma on Aug 22, 2022

Ear relief

After using Zymox plus in my Rottweilers ear, there was no more shaking her head, ear droop, or using her nails to get to her ears. It all went away within 1/2-hour or so. I love this for my dogs ears. Have already recommended it to my daughter for her dogs. I used it once and didn’t follow up daily as the directions state, - and the problem came back about a week later. Therefore follow the directions and use daily until the problem is completely gone.


Rated 5 out of 5 stars
By Jamie on Aug 4, 2022

Cleared my Dog’s Ear Infection

I noticed my Lucy’s ear was smelly, red, very swollen and full of a lot of brown gunk. I called our vet’s office and the soonest appointment they had was 2 weeks out. I remembered I had ordered this Zymox ear product months earlier to have on hand for my other dog that has allergies. In an effort to ease poor Lucy’s discomfort I used this in her uncleaned ear once a day for a little over a week. I stopped using it a few days before her appointment so that they could swab her ear and test it. When it finally came time for her appointment the veterinarian said whatever I had used at home had completely cleared up whatever had been going on with her ear as there was no evidence of any kind of infection. This product definitely works and I highly recommend it!


Rated 5 out of 5 stars
By adraper2323 on Sep 16, 2022

Worked well!

I bought this because my dog got an ear infection after he was just at the vet a few days before. I didn’t want to take him back, so I decided to try something else. I wasn’t sure if it would work, but it did! His ear is completely cleared up now after the 7-day treatment.


Rated 5 out of 5 stars
By Willow on Jul 22, 2022

Amazing product!!

My dog has super bad allergies in the summer and I didn’t wanna keep taking her to the vet for more ear infection medicine. I got her this because her entire ear was red and swollen and smelly and she would scratch it so much she would bleed. after like 25 minutes of the first time applying the swelling went down and the redness was so much better. It was gone in like 4 days. I give it to her regularly still just to keep it maintained and it’s honestly amazing and it completely stopped her itching her ear! Lifesaver for sure


Rated 5 out of 5 stars
By MNTBONE on Jul 2, 2022

Worked wonders!

My groomer recommended this product for one of my pups who shakes her head until she has hematomas, scratches continuously. She has been on allergy meds. I am thinking it has been ear issues?? SERIOUSLY! 3 days treatment and she was 100%. I will keep this on hand always! NOTE: Put directly into uncleared ear canal and massage 1 x daily. I did one day after symptoms ceased then cleaned thoroughly. She has been free of symptoms since treatment.


Rated 5 out of 5 stars
By Scrappydoo on Jul 31, 2022

Highly recommended by our veterinarian

This product was recommended for our black lab, Shadeaux's ears. Her ears were dirty and smelly and causing her a lot of grief. He recommended that we use it every day for a week, but after two days, she was already feeling so much better.


Rated 3 out of 5 stars
By Packageproblems on Aug 13, 2022

1.25 oz mess

The product seems to work well enough. However, the bottles got even cheaper. First use the nose shot off with a gentle squeeze, filling my dog's ear and making a $30+ mess.