Douxo S3 CALM Soothing Itchy, Hydrated Skin Dog & Cat Mousse, 5.1-fl oz bottle

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At a Glance

  • Itch & Redness Remedy
  • All Lifestages
  • All Breeds
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$28.99 Chewy Price
($5.69 /fl oz)
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About This Item

Details

  • Mousse soothes allergic, itchy or irritated skin for dogs and cats.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.
  • Helps restore the balance of protective microbes.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

Ingredients

Instructions

Dermatological Treatment for Skin Issues

Developed with veterinary dermatologists, Douxo S3 offers expert solutions for pets with skin issues. The range includes shampoos, mousses, and pads—designed for daily use and to meet specific skin needs.

Made to Manage Common Skin Conditions

Douxo S3 is made to help manage common skin conditions like allergies, yeast or bacterial overgrowth, and seborrhea. Free from sulfates, parabens, colorants, and silicones, it’s pH-adjusted, soap-free, and hypoallergenic.

Featuring High-Performing Ingredients

 All Douxo S3 formulas contain Ophytrium, a natural-origin, triple-action ingredient that soothes, rebalances and strengthens the skin barrier. Other high-quality ingredients are selected to provide specific benefits in each formula. 

Easy Care for Pleasant Moments

Douxo S3 is designed to make every routine more pleasant for pets and people, with delightful textures and scents and ergonomic packaging. Co-developed with pet parents, it offers a complete skincare solution that’s easy and enjoyable to use.

About Douxo

Backed by 20+ years of expertise in veterinary dermatology, Douxo is designed to make grooming a better experience for both you and your pets.            

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Questions & Answers

11 Customer Questions

My dog has some open wounds from scratching so hard. Can you use this mousse on open wounds? I do not want it to burn.

Answer by Chewy • Jul 09, 2021
Douxo S3 CALM Soothing Itchy, Hydrated Skin Dog & Cat Mousse is for external use only.

Is it safe/non-toxic if a cat or dog licks it after it’s applied?

Answer by Chewy • Apr 06, 2021
This mousse is not toxic if a pet licks it after application. It is recommend to let the product dry as long as possible to increase its effectiveness.

Will this help itchy irritated red skin well it helps stop itching

Answer by Chewy • Oct 23, 2021
The mousse soothes allergic, itchy or irritated skin for dogs and cats. It will help calm the skin with natural ingredients like ophytrium, which helps strengthen the skin’s physical barrier.

Can this product go on dogs head or in between eyes or wrinkles?

Answer by Chewy • May 11, 2023
This product is suitable for all over use with care so that mouth and eyes are avoided.
Reviews
Write a Review
4.3
Rated 4.3 out of 5 stars
667 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Durability

67% Positive

Ease of Use

77% Positive

Effectiveness

75% Positive

Safety

75% Positive

234 Customer Reviews

Rated 2 out of 5 stars
By Jo on Jan 6, 2026

Bottle extremely leaky

I didn’t get a chance to use this product more than twice, because when I stored it in a drawer on its side, it ALL leaked out. I first noticed it leaking when it

I didn’t get a chance to use this product more than twice, because when I stored it in a drawer on its side, it ALL leaked out. I first noticed it leaking when it was just sitting upright in my counter, and figured it was just some seepage after using it. I may have gotten a defective bottle though because the entire contents fully came out over the course of a week or so into my medicine drawer. Fortunately it smells really nice!

Rated 1 out of 5 stars
By Sarah on Dec 13, 2025

overpowering scent gave me a headache

I tried this on my dog twice - both times, the scent bothered me so much that it gave me a headache just to apply it to my dog, so I gave up after that. If the

I tried this on my dog twice - both times, the scent bothered me so much that it gave me a headache just to apply it to my dog, so I gave up after that. If the scent was so overpowering to me, what must it have been like for my dog, whose sense of smell is hundreds of times better than mine?

Rated 5 out of 5 stars
By Joanne on Jan 15, 2026

Worked well

I used this on several spots of redness with little red bumps on her belly. By the next morning they were all gone. It’s nice to have a product that works!

I used this on several spots of redness with little red bumps on her belly. By the next morning they were all gone. It’s nice to have a product that works!

Rated 4 out of 5 stars
By Makayla on Jan 13, 2026

Vet recommended

As a professional groomer for a vet office, and the owner of an allergy riddled dog myself, Douxo products are extremely effective when used properly!

As a professional groomer for a vet office, and the owner of an allergy riddled dog myself, Douxo products are extremely effective when used properly!

Rated 3 out of 5 stars
By Marcia on Dec 28, 2025

Arrived leaking

I like the product but there was an issue with shipping . The bottle arrived leaking and considering how much it cost per ounce I felt like I waisted some money

I like the product but there was an issue with shipping . The bottle arrived leaking and considering how much it cost per ounce I felt like I waisted some money.

Rated 3 out of 5 stars
By Catherine on Nov 29, 2025

I liked the ease of applying the product.

However, after each of the two applications, Tigger continued to excessively bathe himself due to the dermatitis. I was concerned about his ingesting this product

However, after each of the two applications, Tigger continued to excessively bathe himself due to the dermatitis. I was concerned about his ingesting this product and reducing the effectiveness of the mousse due to his saliva.

Rated 5 out of 5 stars
By Dawna on Nov 27, 2025

My skin saver!!!

I love Douxo S3 soothing skin mousse because it instantly relieves my itchy skin. I use it with the Douxo S3 soothing shampoo. They make my hair look extra fluffy,

I love Douxo S3 soothing skin mousse because it instantly relieves my itchy skin. I use it with the Douxo S3 soothing shampoo. They make my hair look extra fluffy, shiny and feeling great!

Rated 4 out of 5 stars
By Melissa on Sep 17, 2025

Worked as advertised

My cat had several fleas bites on her neck. She was all scabby and raw. The Chewy on line vet advised that my cat was having an allergic reaction to fleas. Even

My cat had several fleas bites on her neck. She was all scabby and raw. The Chewy on line vet advised that my cat was having an allergic reaction to fleas. Even though flea meds were administered, my cat was still scratching and having a reaction. Applying this foam lotion helped. I applied 2pumps daily or every other day. Rubbed it in well. After a few days I already saw improvement in her skin. I continued to groom her with a flea comb to help remove crusty skin. Reason 4 stars. Dosing instructions on bottle are vague and confusing. Pumps by weight didn’t seem right. I probably under dosed to be safe. With consistent treatment product worked. Product is light. Dries quick. No smell. Not sticky. I recommend for cat skin irritations. My cat’s inflamed skin was pretty servere and this product helped.

Rated 4 out of 5 stars
By Kim on Dec 18, 2025

Chewy Vet recommended

I like the texture of the mousse foam texture over a spray. Seems to sooth the coat better and can be massaged into the skin nicely. Has a nice scent, as well

I like the texture of the mousse foam texture over a spray. Seems to sooth the coat better and can be massaged into the skin nicely. Has a nice scent, as well.

Rated 1 out of 5 stars
By Alisha on Oct 26, 2025

Stinks up your hands

I am not sure what they put in it. But it smelled musky. Like I washed it off my hands right after putting it on her. My hand smelled off for hours. At first I kept

I am not sure what they put in it. But it smelled musky. Like I washed it off my hands right after putting it on her. My hand smelled off for hours. At first I kept looking around the house for the thing that smelled moldy only to realize it was the residue from the cat foam