Frontline Plus Flea & Tick Spot Treatment for Medium Dogs, 23-44 lbs
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Powerful Prescription Protection
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About FRONTLINE Plus for Dogs


#1 Name in Flea and Tick Protection*
FRONTLINE Plus is proven flea and tick protection that has been trusted by pet parents for over 20 years.** Just one dose of FRONTLINE Plus provides fast-acting protection that lasts for a full 30 days.
Break the Flea Life Cycle
FRONTLINE Plus contains fipronil, which kills adult fleas, as well as (S)-methoprene, which kills flea eggs and larvae. Together, these active ingredients break the flea life cycle, prevent future infestations, and provide continuous protection for a full month.
Protect Your Dog Here, There and Everywhere
Fleas and ticks can be found at the park, the lake and in your own backyard. That’s why it’s important to keep your dog protected month after month.

The #1 Name
FRONTLINE is the #1 name in flea and tick protection.*

Long-Lasting Protection
One dose of FRONTLINE Plus for Cats lasts a full 30 days.

Fast-Acting Formula
Once applied to your cat, this powerful formula kills fleas, ticks and chewing lice on contact.

Waterproof
FRONTLINE Plus is waterproof 24 hours after application.

Trusted Protection
FRONTLINE Plus has been trusted by pet parents for over 20 years.**

Effective for Puppies
FRONTLINE Plus for Dogs can be used on puppies as young as 8 weeks and weighing at least 5 lbs.

For Dogs Big and Small
Choose from four formulas—Small 5-22 lbs., Medium 23-44 lbs., Large 45-88 lbs., and Extra-Large 89-132 lbs.

Formulation Available for Cats
Protect your cats with FRONTLINE Plus for Cats!
Pests Can Be a Year-Round Threat
Flea infestations usually begin 6-8 weeks before you ever notice a flea on your dog, and once your home is infested, it can take up to 90 days to eliminate all stages of the flea life cycle. Protecting your dog with FRONTLINE Plus monthly, year-round can help prevent reinfestations.

Protect Year-Round with Autoship
Sign up for Autoship today and save on FRONTLINE Plus. You’ll get a discount on every order of FRONTLINE Plus, and you can rest easy knowing that you’ll never run out of proven flea and tick protection.

The Mission
Boehringer Ingelheim, the maker of FRONTLINE Plus, is committed to enhancing the well-being of pets and supporting the animal health community through science and innovation. No animal should have to suffer a preventable disease, which is why Boehringer Ingelheim develops products like FRONTLINE Plus.
About FRONTLINE Plus
FRONTLINE Plus is the #1 name in flea and tick protection.* It’s formulated with two active ingredients that kill fleas and ticks and prevent new flea infestations from developing. FRONTLINE Plus is waterproof 24 hours after application, lasts for a full 30 days and has formulations available for dogs and cats. With FRONTLINE Plus, you can take your pet everywhere.

* Data on file at Boehringer Ingelheim
** Data on file at Boehringer Ingelheim
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Customer Rating | |||||
Price | $88.99Chewy Price | $88.99Chewy Price | $71.99Chewy Price | $82.67Chewy Price | $74.37Chewy Price |
Autoship | $84.54Chewy Price | $84.54Chewy Price | $68.39Chewy Price | $78.54Chewy Price | $70.65Chewy Price |
Top Ingredients | Active Ingredients : Fipronil 9.8% , (S)-methoprene 8.8%. | Active Ingredients : Fipronil 9.8% , (S)-methoprene 8.8%. | Active Ingredients : Fipronil 9.8% , (S)-methoprene 8.8%. | Active Ingredients : Fipronil 9.8% , (S)-methoprene 8.8%. | Active Ingredients : Fipronil , (S)-methoprene , Pyriproxyfen. |
Lifestage | Adult, Senior, Puppy | Puppy, Adult, Senior | Adult, Puppy, Senior | Adult | Adult, Puppy, Senior |
Breed Size | Small Breeds, Medium Breeds | Extra Small & Toy Breeds, Small Breeds | Medium Breeds, Large Breeds | Large Breeds | Medium Breeds |