Frontline Plus Flea & Tick Spot Treatment for Small Dogs, 5-22 lbs, 3 Doses (3-mos. supply)

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About This Item

Details

  • Promotes fast-acting, long-lasting and waterproof protection from fleas and ticks.
  • Each treatment helps protect against fleas and ticks for 30 days.
  • Works to kill adult fleas, flea eggs, flea larvae, chewing lice and ticks.
  • It also helps aid in the control of sarcoptic mange infestations.
  • Formulated with two active ingredients to help disrupt the flea life cycle and prevent new infestations.

Ingredients

Instructions

Size

FAQ

Learn More About Frontline Plus From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 90 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

Fast-Acting, Long-Lasting Protection

Frontline Plus is formulated with two active ingredients that kill fleas and ticks and prevent new flea infestations from developing. It’s waterproof 24 hours after application, lasts for a full 30 days, and comes in formulas for cats or dogs.

Easy One-Spot Topical Application

Frontline Plus is a spot-on solution that’s available without a prescription. 1 dose = 30 days of protection.

Protects Your Pet

  • Starts killing fleas and ticks fast and protects against reinfestation.
  • Waterproof for a full 30 days starting 24 hours after application.
  • Monthly dosing keeps your dog protected for every season.

How to Apply

Follow these simple steps for application:

  1. Hold upright with foil side toward you and snap applicator tip.
  2. Part hair and apply on shoulder blades, completely emptying the pipette.
  3. Leave the solution to spread through your pet's coat.

About Frontline Plus

To ensure your dog stays protected from fleas and ticks all year round, treat them monthly with Frontline Plus. This simple, easy, one-spot topical solution helps keep your pet free from infestations, providing you with peace of mind.

Shop Frontline Plus

Questions & Answers

33 Customer Questions


What is the difference between Frontline Gold and Frontline Plus? Does one handle tick resistance better?


Does frontline plus expire

Answer by ChewySep 19, 2019
This product doesn't expire. It will be usable until each individual dosage is opened.

Is this safe for dogs under 5lbs?

Answer by ChewyDec 31, 2023
Frontline Plus for Small Dogs & Puppies is for 5-22 pounds. For smaller dogs, consult with a veterinarian to determine the best method of protection.

Does it continue to work after bathing dog or do you need to reapply?

Answer by ChewyApr 03, 2018
This treatment provides waterproof effectiveness so that it won't wash off from swimming or baths.

4.4
Rated 4.4 out of 5 stars
6338 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

82% Positive

Effectiveness

81% Positive

Ingredients

80% Positive

Long-Term Benefits

82% Positive

2529 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 1 out of 5 stars
By Faustin on Dec 30, 2025

Buyer Beware

This is my first product review EVER. Recently switched my Cavalier from K9 Advantix ll to this and within a month she had fleas for the first time ever. I even

This is my first product review EVER. Recently switched my Cavalier from K9 Advantix ll to this and within a month she had fleas for the first time ever. I even reapplied it and it did nothing, ended up having to take her to the vet for a prescription of NexGard which cleared it up within 24 hours. Sorry but this product was an absolute flop for us.


Rated 1 out of 5 stars
By Cindy on Dec 31, 2025

Delivery of the item stinks

The delivery people said it was delivered to our door we went looking for it checked all three doors and did not see it my husband went looking for it and found

The delivery people said it was delivered to our door we went looking for it checked all three doors and did not see it my husband went looking for it and found it in the middle of the yard If we didn’t go looking for it, it could’ve froze and I’m not sure how it would be after freezing


Rated 2 out of 5 stars
By Judy on Dec 10, 2025

Delivery issues, negative

The product was left in snow at a neighbor's house by TedEx and wasn't found for a week. My mail carrier saw it and brought it to me. I'm not sure if the flea/tick

The product was left in snow at a neighbor's house by TedEx and wasn't found for a week. My mail carrier saw it and brought it to me. I'm not sure if the flea/tick treatment is useable after being frozen that long. Please advise if you think it is still okay to use.


Rated 1 out of 5 stars
By Amy on Nov 9, 2025

Became ineffective to fleas

My dog has been in frontline since he was a puppy. Just within the last month or so, he has started getting fleas, even while taking frontline monthly. Flea baths

My dog has been in frontline since he was a puppy. Just within the last month or so, he has started getting fleas, even while taking frontline monthly. Flea baths didn’t work either. Had to go to the vet for a Rx flea medicine. I was told at the vet clinic Frontline is increasingly becoming ineffective on fleas, they seem to have built up a resistance. Do not buy, you will be wasting your money and have a miserable dog with fleas.


Rated 5 out of 5 stars
By Nona on Dec 10, 2025

Excellent Flea and tick protection

I went to Frontline because my other flea and tick was making my dogs itch. They have skin allergies. Frontline is perfect. No more itch and you only put it on

I went to Frontline because my other flea and tick was making my dogs itch. They have skin allergies. Frontline is perfect. No more itch and you only put it on one spot on their back rather than several spots down their spine. Very happy with this product.


Rated 5 out of 5 stars
By Deborah on Dec 13, 2025

Fast Shipping & Peace of Mind

Found a tick on my small dog recently. Wasn't expecting that given the cold temperatures. I was so happy that Chewy could deliver this topical treatment so quickly

Found a tick on my small dog recently. Wasn't expecting that given the cold temperatures. I was so happy that Chewy could deliver this topical treatment so quickly. Gave me such peace of mind knowing he's protected moving forward!


Rated 1 out of 5 stars
By Lagina on Oct 10, 2025

Doesn’t Work

I applied the first dose two weeks ago, and the fleas came back with a vengeance. I usually use Bravecto, which works much better, but I switched to Frontline because

I applied the first dose two weeks ago, and the fleas came back with a vengeance. I usually use Bravecto, which works much better, but I switched to Frontline because my dog has liver issues and IBD, and I didn’t want to take any risks. Unfortunately, this product just doesn’t work. I’ve had to use flea shampoo and flea spray in the meantime which he hates lol until I can get Bravecto again hoping it works and doesn’t upset his stomach, because at least that actually gets the job done. It’s frustrating that I have to wait another two weeks to reapply this one. To be honest, very disappointed.


Rated 5 out of 5 stars
By Lina on Nov 2, 2025

Long time user of this product

I have used FRONTLINE for about 30+ years on all my small dogs and the product seems to work as it should every time. Thus, once my dog has the product put on him/her,

I have used FRONTLINE for about 30+ years on all my small dogs and the product seems to work as it should every time. Thus, once my dog has the product put on him/her, then I've never seen any of my dogs ever get ticks or fleas once the FRONTLINE product is used ----as according to the instructions.


Rated 5 out of 5 stars
By Sheryl on Nov 16, 2025

Easy application

My pup stays nice and still when I apply this to his back (between shoulders). He doesn’t mind this and he hated the oral treat that was so much more expensive

My pup stays nice and still when I apply this to his back (between shoulders). He doesn’t mind this and he hated the oral treat that was so much more expensive. Better and cheaper to use this topical. No fleas and no ticks either!


Rated 4 out of 5 stars
By Eric on Jan 9, 2026

Tick and flea control for my big pup Harrigan.

Works well keeping the fleas away. Does not work controlling ticks. Seresto was purchased for tick control. That works well!

Works well keeping the fleas away. Does not work controlling ticks. Seresto was purchased for tick control. That works well!