Hill's Prescription Diet Gastrointestinal Biome Stress Digestive/Fiber Care with Chicken Dry Cat Food, 4-lb bag

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About This Item

Details

  • Specially crafted by Hill’s nutritionists and vets to support your pet’s digestive health.
  • Promotes regular, healthy stool.
  • Contains ActiveBiome+ ingredient technology to help activate beneficial gut bacteria and support a healthy GI microbiome balance.
  • Features a proprietary blend of prebiotic fibers to promote regular bowel movements and help balance digestion.
  • Contains generous levels of omega-3 fatty acids, DHA and EPA.

Ingredient Information

Feeding Instructions

FAQ

Learn More About Hill's Prescription Diet From Our Team of Experts

Digestive Care Nutrition

Hill’s offers a variety of digestive care foods that help promote a healthy gut microbiome, with easy-to-digest ingredients that are gentle on tummies.

Signs of Distress or Digestive Upset

A pet experiencing stress or digestive upset may exhibit an upset stomach, loose stool, constipation, flatulence and/or weight loss.

What Can Affect a Pet’s Digestion?

There are several factors that can play a role in digestive upset, including dietary indiscretion, infection, gut inflammation and stress.

Recommended by Veterinarians

Hill’s is a leader in cutting-edge food science and research, trusted and recommended widely by vets.

About Hill’s Pet Nutrition

In 1948, Hill’s changed the pet nutrition world by launching the first veterinarian-prepared food for a pet’s specific health needs. Seven decades and thousands of innovations later, they are still leading the charge in science-led nutrition.

Shop Hill's Prescription Diet

Questions & Answers

21 Customer Questions


Is this a hydrolyzed protein food?

Answer by ColeCJan 18, 2026
This food is not made with any hydrolyzed proteins, for a full list of ingredients you can check the "Ingredient Information" tab under the food's description.

what is biome in the food?

Answer by ChewyNov 21, 2019
Hill's ActivBiome Technology is a mixture of active fibers that may help improve regularity.

How many calories this cat food?

Answer by ChewyFeb 24, 2025
This recipe contains 421 calories per cup.

What is the phosphorus content on a dry matter basis?

Answer by ChewyMar 02, 2023
This formula contains a phosphorus content of 0.66% on an as-fed basis and 0.7% on a dry matter basis.

4.7
Rated 4.7 out of 5 stars
2781 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Digestibility

87% Positive

Ingredient Quality

88% Positive

Nutritional Content

87% Positive

Palatability

82% Positive

1143 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Patricia on Jan 20, 2026

Resolved diarrhea in less than 24 hours

I adopted a 2 year old cat and she had diarrhea since day 1, even though I was feeding her the same food from the shelter. I tried other foods, adding psyllium

I adopted a 2 year old cat and she had diarrhea since day 1, even though I was feeding her the same food from the shelter. I tried other foods, adding psyllium and probiotics and nothing helped. The vet did a thorough exam and diagnosed that her intestines were inflamed and recommended Hills Prescription GI Biome. I was skeptical because I’m not a fan of the so-called “prescription” foods. Anyway, the vet gave me a sample and since my cat already had severe diarrhea I didn’t bother with a slow transition and fed her that evening with Hills. I was surprised how much my very picky cat liked the food. The bigger shock came the next day when she had her first normal poop. This food works.


Rated 5 out of 5 stars
By Linda on Nov 18, 2025

5 Month Old Rescue Kittens Love This Food

I rescued 5 month old kittens. They were vomiting and had loose stools. Tested negative for disease and worms. It was their food! Their vet prescribed this kibble

I rescued 5 month old kittens. They were vomiting and had loose stools. Tested negative for disease and worms. It was their food! Their vet prescribed this kibble and the Hill's wet food. The kittens loved the kibble but not the wet food. No more loose stools or vomiting! If it wasn't so expensive I would continue to feed them this food. I kept them on it for two months and gradually switched to the nonprescription Hill's Sensitive Stomach and Skin kibble. I also switched them to another brand of limited ingredient wet food. That's another review.


Rated 5 out of 5 stars
By Amanda on Dec 5, 2025

Instant stool results

Amazing. I purchased high end food for my kitten with no luck. He had loose stools and blood present. Parasites from a cattery was the cause. Ronidazole isn’t available,

Amazing. I purchased high end food for my kitten with no luck. He had loose stools and blood present. Parasites from a cattery was the cause. Ronidazole isn’t available, so diet and probiotics are just about the only remedy to help. GI Biome worked so well and in less than 24 hours the stools improved. Thank god. What a mess to deal with.


Rated 1 out of 5 stars
By Tamara on Nov 13, 2025

It shipped and it shouldn't have

My cat hasn't had a valid prescription in some time because we changed her food type and no longer use chewy. Suddenly I am charged allot of money for food that

My cat hasn't had a valid prescription in some time because we changed her food type and no longer use chewy. Suddenly I am charged allot of money for food that didn't have a valid prescription and shouldn't have been shipped. Now to get a return I am sent a FedEx label and with my work schedule I can't get it dropped off during they opening hours! So I am out a ton of money. Never again chewy. I heard good things about your service but shipping something that shouldn't be shipped and I can't get a refund!


Rated 1 out of 5 stars
By Sandra on Nov 28, 2025

Had such high hopes.

My veterinarian recommended this product for my cat. Unfortunately, after completing the entire bag, there was no change in my cat’s gastrointestinal issues. I know

My veterinarian recommended this product for my cat. Unfortunately, after completing the entire bag, there was no change in my cat’s gastrointestinal issues. I know that Hill’s Biome is an excellent product, and that’s why I was so excited to try it. No discouragement whatsoever, we will continue to push forward and find the proper solution for his issues.


Rated 5 out of 5 stars
By Mona on Nov 25, 2025

Cats Love the Taste

I was surprised when my 2 cats loved this prescription food. I've had several cats over the years who have had different presciption foods prescribed. They hated

I was surprised when my 2 cats loved this prescription food. I've had several cats over the years who have had different presciption foods prescribed. They hated them all so I was prepared for my current cats to refuse to eat this one. I bought the smallest bag so I could test it out. Since they liked it so much, I'm now wishing I had gotten a bigger bag.


Rated 5 out of 5 stars
By Gabrielle on Jan 12, 2026

Smooth Ordering

This food is as prescribed by our vet. She really likes it. This requires a prescription but this was a very smooth process and took a couple of days for our vet

This food is as prescribed by our vet. She really likes it. This requires a prescription but this was a very smooth process and took a couple of days for our vet to authorize


Rated 5 out of 5 stars
By Gina on Jan 14, 2026

Healthy

Ever since I have left Biome Kitty Food in their bowl - 24/7 - the 4 only eat it when they are hungry between wet food meals. Their potty habits have been perf

Ever since I have left Biome Kitty Food in their bowl - 24/7 - the 4 only eat it when they are hungry between wet food meals. Their potty habits have been perfect.


Rated 5 out of 5 stars
By Allegra on Jan 16, 2026

Great food for kitties with upset stomachs!

My cat has had some issues with GI upset and this food made him feel a lot better. He is more regular and has less diarrhea. Would recommend! Worth the price.

My cat has had some issues with GI upset and this food made him feel a lot better. He is more regular and has less diarrhea. Would recommend! Worth the price.


Rated 5 out of 5 stars
By Lynda on Nov 6, 2025

You would think it was catnip.... they enjoyed it

I bought this for our one boy, Red Adair. Like most households the cats do not keep to their bowls - it is like a FREE For ALL :-) So far so good. Red Adair enjoys

I bought this for our one boy, Red Adair. Like most households the cats do not keep to their bowls - it is like a FREE For ALL :-) So far so good. Red Adair enjoys the food, but I do not only feed him dry food. These boys have a wet food diet. The Biome Dry Food is in place of "Treats" - our boy Red Adair has dietary issues and needs this more than his treats. So yes I am tricking him. But all the cats LOVE this food.