Sentinel Flavor Tablets for Dogs, 26-50 lbs, 6 treatments

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Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Sentinel is a monthly oral preventive prescription that guards against heartworms, adult roundworms, adult hookworms, whipworms, and prevents the development of flea eggs. It protects your dog against heartworm disease and intestinal worms, all in a palatable, flavored tablet.


Sentinel Flavor Tabs are formuled for dogs and puppies, four weeks of age and older, and two pounds body weightnor greater. T It is also formulated to help prevent and control flea populations, and for the treatment and control of adult roundworm, hookworm and whipworm infections. Concurrent use of an adulticide product may be necessary for adequate control of adult fleas.

Possible Side Effects

The following adverse reactions have been reported in dogs alter giving milbemycin oxime or lufenuron: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation, and weakness.

Drug & Food Interactions

Talk to your veterinarian about any other drugs your dog is taking before starting this medication.


Do not use in puppies less than four weeks of age and less than two pounds of body weight. The temporary use of an adulticide product may be necessary to kill these adult fleas. Not for use in humans. Keep this and all drugs out of the reach of children.

  1. Prescribing Information

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  • Item Number
  • Dosage Measure

    Use according to your veterinarian's instructions.

  • Generic Name

    Milbemycin Oxime, Lufenuron

  • Common Brand Name(s)


  • For Use With


  • Brand


  • Breed Size

    Medium Breeds

  • Product Form


  • Health Condition

    Heartworms, Roundworms, Hookworms, Whipworms, Fleas

  • Drug Type



Milbemycin Oxime, Lufenuron

Recommended Dosage

Sentinel Flavor Tabs are given orally, once a month, at the recommended minimum dosage ofn0.23 mg/lb (0.5 mg/kg) milbemycin oxime and 4.55 mg/lb (10mg/kg) lufenuron.nDogs over 100 lbs are provided the appropriate combination of tablets.n

Storage Instructions

Store in a dry place at controlled room temperature between 59° - 77°F.

SENTINEL SPECTRUM should be administered orally, once every month, at the minimum dosage. To ensure adequate absorption, always administer SENTINEL SPECTRUM to dogs immediately after or in conjunction with a normal meal. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.

Heartworm Prevention: SENTINEL SPECTRUM should be administered at monthly intervals beginning within 1 month of the dog’s first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog’s last seasonal exposure. SENTINEL SPECTRUM may be administered year-round without interruption. When switching from another heartworm preventative product to SENTINEL SPECTRUM, the first dose of SENTINEL SPECTRUM should be given within a month of the last dose of the former product.

Flea Treatment and Prevention: Treatment with SENTINEL SPECTRUM may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with SENTINEL SPECTRUM should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product, as necessary.

Intestinal Nematode and Cestode Treatment and Control: Dogs may be exposed to and can become infected with roundworms, whipworms, hookworms, and tapeworms throughout the year, regardless of season or climate. Clients should be advised of appropriate measures to prevent reinfection of their dog with intestinal parasites. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.


How are Sentinel Spectrum and Sentinel Flavor Tabs different from other heartworm medications?

Not all heartworm medicines provide the same spectrum of parasite protection. Sentinel Flavor Tabs are chewable tablets that protect dogs against fleas, heartworms, roundworms, hookworms, and whipworms. Sentinel Spectrum is a soft, beef and bacon flavored chew that adds tapeworm protection to offer the broadest coverage available.

My dog weighs more than 100 pounds. Are Sentinel Specturm or Sentinel Flavor Tabs a good option for him?

Yes. Talk to your veterinarian about the appropriate dose for your pet.

My dog is a toy breed. Are Sentinel Specturm or Sentinel Flavor Tabs okay for his small size?

Yes. Both Sentinel Specturm and Sentinel Flavor Tabs offer a size that can be given to small dogs. Sentinel Spectrum has a size available for dogs weighing from 2–8 lbs and Sentinel Flavor Tabs has a size available for dogs weighing from 2–10 lbs.

I see a few fleas on my dog. Is the medication working?

You may see an occasional “hitchhiker” adult flea that your dog has picked up at the dog park or in the yard or other infested environments where 95% of the flea population lives in the form of eggs, maggot-like larvae, and pupae. Sentinel Specturm and Sentinel Flavor Tabs put an end to fleas before they become adults. You may need an adulticide, such as Effitix Topical Solution for Dogs, to treat occasional adult fleas.

Can I give either Sentinel Spectrum or Sentinel Flavor Tabs to my cat?

No, both Sentinel Spectrum and Sentinel Flavor Tabs are only approved for use in dogs.

Customer Reviews
15 Reviews 15 Reviews 4.7 out of 5 Stars

93% Recommend

93% of reviewersrecommend this product

4.7 / 5

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  • Great product!

    By on

    I've been giving this to my dog for...oh at least 5 yrs if not more and it works great! This product really protects against heartworms and kills fleas before they hatch. The tab is very tasty to my dog and she loves it.

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  • Great Product & Great Price!

    By on

    I always treat my Beagle with Sentinel every month for heartworm protection. I feel that this is a great product at a great price-Vet recommended.

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  • Doesn’t seem to work

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    i started giving my puppy sentinel about 2 weeks ago but she’s picked up some fleas and is constantly scratching. I started giving her sentinel before she had fleas and given the fact that she now has fleas leads me to believe it’s not working. I’ve used similar products in the past and have not had this issue. I’m definitely going to seek a refund and switch to another brand.

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  • HW Protection

    By on

    I really enjoyed getting these and knowing that our 10 furbabies will again be protected for another month from heartworms. Every month 1 box of yellow and one box of white. Thanks for the excellent service.

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  • great product

    By on

    Protection for my dog and she will eat it and not other products.

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  • Recommend this product

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    The process to get prescription med for my dog was easy.

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  • Sentinel Flavor Tabs

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    I have used Sentinel for quite a long time now and Goldie has always been negative for heart worms. I recommend this product.

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  • Easy chewing

    By on

    Sentinel is our dogs favorite, she thinks it’s a treat and it takes care of heart worm and fleas! Good product!

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  • Great product

    By on

    Great product. Great price. Does what it advertises.

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    By on

    Love the ease, speed and price of working with Chewy

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