Tresaderm Topical Solution for Dogs & Cats, slide 1 of 1

Tresaderm Topical Solution for Dogs & Cats

Prescription Item

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    $20.99 FREE Shipping over $49

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Size: 7.5-mL
  • Click to select 15-mL In stock

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This item is specially packaged to remain refrigerated during transit.

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Tresaderm is a combination ear and skin medication prescribed to dogs and cats. This medication contains an antifungal, corticosteroid and a broad-spectrum antibiotic to treat inflammation, as well as bacterial and fungal infections of the ear and skin. This topical solution comes in convenient drop form, making treatment easier for you and your pet.


Tresaderm is applied directly on the skin or in the ears in order to kill susceptible bacteria, fungus, and yeast. It also helps relieve local inflammation associated with the infection.

Possible Side Effects

Skin irritation and redness at the affected area is possible. If Tresaderm is used on an open wound, it can cause minimal pain for up to 15 minutes. If ingested or used chronically, side effects from the dexamethasone may be noted including increased drinking/urination, vomiting, immune suppression, and weight gain. These side effects can resolve when the dosage is decreased.

Some pets may have an allergic reaction to the ingredients in Tresaderm although this is not common.

Drug & Food Interactions

Interactions are possible with non-steroidal anti-inflammatory drugs (NSAIDs), other corticosteroids, or gentamicin. Other interactions may occur. Discuss all medications/supplements your pet is taking with your veterinarian prior to giving Tresaderm to make sure it can be given safely.


Pets with an allergy to any of ingredients shouldn't use Tresaderm. In dogs birth defects have been reported with the use of corticosteroids. This medication shouldn't be ingested; it's for topical use only. Avoid contact with eyes.


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  1. Package Insert

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  • Item Number
  • Common Brand Name(s)
  • For Use With
    Dogs & Cats
  • Generic Name
    Dexamethasone, Neomycin Sulfate, Thiabendazole Solution
  • Administration Form
    Topical, Otic
  • Brand
    Merial, Boehringer Ingelheim
  • Product Form
  • Health Condition
    Ear Infections, Skin Infections, Fungal Infections
  • Drug Type
    Antibiotic, Antifungal, Anti-inflammatory, Steroid / Corticosteroid

Active Ingredients per mL: Thiabendazole (40 mg), Dexamethasone (1 mg), Neomycin (3.2 mg) (from neomycin sulfate).

Inactive Ingredients: Glycerin, Propylene Glycol, Purified Water, Hypophosphorous Acid, Calcium Hypophosphite; about 8.5% Ethyl Alcohol and about 0.5% Benzyl Alcohol.

Recommended Dosage

Always follow the instructions and guidance provided by your veterinarian. Trim any excess fur, clean and dry the affected area before you apply Tresaderm. If you miss a dose, you can give it as soon as you remember, but never double dose. Always ask your veterinarian if you have questions about how to best use this medication.

Storage Instructions

Store in refrigerator at temperatures between 36° - 46°F.


What are the benefits?

  • Available in a convenient drop form.
  • Broad-spectrum action that can help resolve bacterial and fungal infections plus relieve inflammation.
  • Can be used topically on the skin and in the ears.

What outcomes can be expected?

Tresaderm will kill susceptible organisms that cause infection when used as prescribed. You should notice your pet feeling better and his skin and ears should start to return to normal. Use beyond 7 days could delay wound healing. If your pets skin/ears are not improving after the medication is finished, contact your veterinarian.

How is it given?

  • Always follow your veterinarians prescribed instructions carefully while using this medication.
  • Clean and dry the affected area and trim any excess hair before starting topical treatment with Tresaderm.
  • Apply the prescribed amount of drops and gently massage into the affected area.
  • If you have any questions about how to use Tresaderm, contact your veterinarian. Incorrect use can result in recurring infection or damage to the ear(s).

How does it work?

Thiabendazole is an antifungal agent, dexamethasone is a corticosteroid and neomycin is a broad-spectrum antibiotic. These ingredients help to kill susceptible bacteria and fungi/yeast plus relieve associated inflammation.

Rating: 4.8 of 5 stars 31 Reviews 31 Reviews 4.9 out of 5 Stars

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Rating: 4.8 of 5 stars 4.9 / 5

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31 Reviews

Showing 1-10 of 31 Reviews

  • 5 out of 5 stars

    Chewy To The Rescue!!

    By on

    My poodle (Quita) is prone to ear infections, and with the stay-at-home order, it made it difficult to get her into the vet. Chewy To The Rescue!! I ordered the medication my wonderful vet had previously prescribed, and Chewy jumped into action. It was delivered SO FAST! The medicine arrived in a cooler with two ice packs--amazing! My sweet Quita was on the mend in no time!

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  • 5 out of 5 stars

    Works for my boy!

    By on

    First of all, Thank you Chewy for delivering this to our home when we couldn't get to the Vets office because of Lockdown restrictions! When we adopted our boy he had ear infections and Tresaderm was the only thing that worked. He started with another and Chewy delivered well packed with ice packs and in a cooler, again THANK YOU!!!!!

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  • 5 out of 5 stars

    Review of service, as well as product

    By on

    Tresaderm is Tresaderm: an effective option for my dog's frequent ear infections. However, it has to be refrigerated and requires special shipping considerations. As always, Chewy rose to the occasion: they shipped it on time, kept it refrigerated, and went above and beyond to make sure it got to us efficiently and intact. Thank you so much!

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  • 5 out of 5 stars

    Excellent Pkg from Chewy

    By on Top 1000 Contributor

    I previously got this med from the vet. This is my 1st time order this med from Chewy and I have to say, I'm very impressed the way this med packed and shipped in cool gel packs inside foam box. Thanks so much for the great service. :)

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  • 2 out of 5 stars

    Not happy with prescription service

    By on

    Took a long time for the pharmacy to get ahold of my vet. Many emails back and forth to get this done. Package on bottle and all paperwork with this didn’t tell amount to give.

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  • 5 out of 5 stars

    Got it for my dog's chronic ear infection

    By on

    My dog's vet prescribed these drops for my dog's chronic ear infection and I have you say that I am beyond impressed how well Chewy packaged and shipped the medication, and it was $10 less than at the vets'. These otic drops have to be refrigerated and I was concerned that it would spoil in the travel but Chewy packed it in a cooler with frozen packs and it reached my home in two days nice and cold. The drops are use to treat yeast in the ears and they work.

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  • 5 out of 5 stars

    Effective ear medication

    By on

    tresaderm is a good med to treat ear infections, when used diligently and when following doctor’s instructions, it works very well.

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  • 5 out of 5 stars

    Finally gone!

    By on

    After trying 3 different ear treatments for my dog’s ear infection, this finally knocked it out in 3 days. Worked so well and didn’t need a ton of product to do the job.

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  • 5 out of 5 stars

    Miracle worker!

    By on

    Used to treat a clowder of 15 rescue cats and it worked wonders while it lasted. My only wish is that it was available in a larger quantity sized bottle. One 15 ml bottle only lasted barely 2 days.

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  • 5 out of 5 stars

    Tiny bottle

    By on

    In an enormous box. I should have checked the size. It did the job.

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