Tresaderm Topical Solution for Dogs & Cats, slide 1 of 1

Tresaderm Topical Solution for Dogs & Cats

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Size: 7.5-mL
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Tresaderm is an FDA-approved combination ear and skin medication prescribed to dogs and cats. This medication contains an antifungal, corticosteroid and a broad-spectrum antibiotic to treat inflammation, as well as bacterial and fungal infections of the ear and skin. Tresaderm contains an anti-fungal, a broad-spectrum antibiotic, and a corticosteroid. This triple action formulation is effective against common causes of fungal and bacterial skin infections, as well as ear infections of the external ear canal. It also acts as an anti-inflammatory for relief from the discomfort caused by these conditions. For pets suffering from otitis externa or skin irritation, it’s recommended to treat the affected area as soon as possible with Tresaderm to help prevent further inflammation. This topical solution comes in convenient drop form, making treatment easier for you and your pet. There are two bottle sizes available (7.5mL and 15mL).


TRESADERM (thiabendazole, dexamethasone, neomycin sulfate solution) is for topical use only in dogs and cats. On rare occasions, application of the product may result in erythema or discomfort in the treated area. Discomfort in the treated area can last from 24 hours to 48 hours

Possible Side Effects

On rare occasions dogs may be sensitive to neomycin.

Drug & Food Interactions

Interactions are possible with non-steroidal anti-inflammatory drugs (NSAIDs), other corticosteroids, or gentamicin. Other interactions may occur. Discuss all medications/supplements your pet is taking with your veterinarian prior to giving Tresaderm to make sure it can be given safely.


On rare occasions dogs may be sensitive to neomycin. In these animals, application of the drug will result in erythema of the treated area, which may last 24 to 48 hours. Please call your veterinarian and refer to prescribing information.

  1. Prescribing Information

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  • Item Number
  • Common Brand Name(s)
  • For Use With
    Dogs & Cats
  • Generic Name
    Dexamethasone, Neomycin Sulfate, Thiabendazole Solution
  • Administration Form
    Topical, Otic
  • Lifestage
    Puppy, Kitten, Adult, Senior
  • Product Form
  • Health Condition
    Ear Infections, Skin Infections, Fungal Infections
  • Drug Type
    Antibiotic, Antifungal, Anti-inflammatory, Steroid / Corticosteroid

Active Ingredients per mL: Thiabendazole (40 mg), Dexamethasone (1 mg), Neomycin (3.2 mg) (from neomycin sulfate).

Inactive Ingredients: Glycerin, Propylene Glycol, Purified Water, Hypophosphorous Acid, Calcium Hypophosphite; about 8.5% Ethyl Alcohol and about 0.5% Benzyl Alcohol.

Recommended Dosage

Prior to the administration of Dermatologic Solution TRESADERM, remove the ceruminous, purulent or foreign materials from the ear canal, as well as the crust which may be associated with dermatoses affecting other parts of the body. The design of the container nozzle safely allows partial insertion into the ear canal for ease of administration. The amount to apply and the frequency of treatment are dependent upon the severity and extent of the lesions. Five to 15 drops should be instilled in the ear twice daily. In treating dermatoses affecting other than the ear the surface of the lesions should be well moistened (2 to 4 drops per square inch) with Dermatologic Solution TRESADERM twice daily. The volume required will be dependent upon the size of the lesion.

Storage Instructions

Store in a refrigerator 36 - 46 F (2 - 8 C).


What are the benefits?

  • Available in a convenient drop form.
  • Broad-spectrum action that can help resolve bacterial and fungal infections plus relieve inflammation.
  • Can be used topically on the skin and in the ears.

What outcomes can be expected?

Tresaderm will kill susceptible organisms that cause infection when used as prescribed. You should notice your pet feeling better and his skin and ears should start to return to normal. Use beyond 7 days could delay wound healing. If your pets skin/ears are not improving after the medication is finished, contact your veterinarian.

How is it given?

  • Always follow your veterinarians prescribed instructions carefully while using this medication.
  • Clean and dry the affected area and trim any excess hair before starting topical treatment with Tresaderm.
  • Apply the prescribed amount of drops and gently massage into the affected area.
  • If you have any questions about how to use Tresaderm, contact your veterinarian. Incorrect use can result in recurring infection or damage to the ear(s).

How does it work?

Thiabendazole is an antifungal agent, dexamethasone is a corticosteroid and neomycin is a broad-spectrum antibiotic. These ingredients help to kill susceptible bacteria and fungi/yeast plus relieve associated inflammation.

What is the best number to call regarding any specific product questions?

For any specific product questions, please call Boehringer Ingelheim Animal Health’s customer service line number at 1-888-637-4251.

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