Revolution Plus Topical Solution for Cats, 11.1-22 lbs, (Green Box), 6 Doses (6-mos. supply)

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$161.82 Autoship Price
(-5%)
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$170.34 Chewy Price
($28.39 /ea)
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Medications ship separately. Delivery times may vary.

About This Item

Details

Help protect your four-legged friend from pesky critters with this 6-in-1 broad spectrum monthly Topical Solution for Cats by Revolution Plus. Simply apply the quick-drying, small-volume prescription to help: kill fleas before they lay eggs, kill ticks for a full month, prevent heartworm disease and treat and control roundworms, hookworms and ear mites. This topical medication is suitable for cats and kittens eight weeks of age or older, weighing between 11.1 and 22 pounds.We directly source prescription medications from manufacturers and wholesale distributors registered with the FDA and licensed by applicable state boards. Guaranteed genuine, and where applicable, backed by the manufacturer. One and three count orders of manufacturer-sealed blister packs will arrive in a resealable plastic bag. Please note, due to a manufacturer prompted packaging change, your medication may arrive in new packaging.

Ingredients

Instructions

FAQ

Learn More About Revolution Plus From Our Team of Experts

Veterinarians’ #1 Trusted Choice in Feline Parasite Protection[1]

The Revolution (selamectin) brand has over 25 years of proven protection. Revolution Plus (selamectin and sarolaner topical solution) is the most prescribed medicine for feline parasite defense. It’s available as an easy-to-administer monthly topical solution.

Pest Protection for Indoor & Outdoor Cats

No matter their lifestyle, Revolution Plus protects your cat from the most common parasites:

  • Fleas
  • Tapeworms*
  • 4 Types of Ticks
  • Ear Mites
  • Roundworms
  • Hookworms
  • Heartworm Disease

*Prevents flea tapeworm (Dipylidium caninum) by killing fleas.

Because Every Cat Needs Parasite Protection

It's approved for cats and kittens as young as 8 weeks old, weighing 2.8 lbs or more, and is the only prescription combination preventative that protects against 4 types of ticks.

Protect Your Cat & Earn Rewards From Zoetis

Your 6-or 12-count Revolution Plus purchase may be eligible for Petcare Rewards points. Redeem your points for Rewards toward future vet care and more! Learn More at zoetispetcare.com/rewards

About Zoetis, the Makers of Revolution Plus

At Zoetis, we’ve helped pets live their best lives for over 70 years. Zoetis offers a comprehensive range of products to support your pet’s health—from pest prevention and pain management to allergic itch relief and more. Know that we’ll always be here for you and your pet, no matter what.

Shop Zoetis

IMPORTANT SAFETY INFORMATION

The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Revolution Plus contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information at RevolutionPlusPI.com.

References:

  1. ZMR: Kynetec PetTrak Veterinary Channel Review. Q4 2024. Data on file. Zoetis Inc.

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4.8
Rated 4.8 out of 5 stars
5701 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

91% Positive

Effectiveness

92% Positive

Ingredients

88% Positive

Long-Term Benefits

91% Positive

1854 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Christy on Jan 24, 2026

Comprehensive protection

I live in Florida, where the mosquitoes never sleep and the fleas don’t either. That means my kitties need to be protected against everything. This is the only thing

I live in Florida, where the mosquitoes never sleep and the fleas don’t either. That means my kitties need to be protected against everything. This is the only thing that works for my two cats. They are indoor outdoor, but they never leave the backyard still, there’s a lot of critters back there, and this has prevented them from catching worms and fleas year-round. I wish it were a little less expensive., but I love that chewy offers it in single doses so that I can buy it every month and it’s the same price as if I bought three of them in a package

Rated 1 out of 5 stars
By YIBO on Jan 17, 2026

Caused sore spot at the site of application

I’ve used Revolution many times but this time it caused my cat to develop a sore spot at the site of application. The sore spot doesn’t seem to go away even after

I’ve used Revolution many times but this time it caused my cat to develop a sore spot at the site of application. The sore spot doesn’t seem to go away even after 3 weeks so I had to go to the vet to seek treatment for my cat. I attached a picture of my cat’s sore spot on his neck. I don’t think I’ll ever use Revolution for flea and tick prevention anymore.

Rated 5 out of 5 stars
By Alaina on Dec 13, 2025

Easy to apply and incredibly effective!

Finally! Vet pharma came out with an effective all in one product to treat and protect our fur babes! We live on an acreage and I'm fairly certain there's an orange

Finally! Vet pharma came out with an effective all in one product to treat and protect our fur babes! We live on an acreage and I'm fairly certain there's an orange cat distribution center close by, bc we've had a couple strays. With my overwhelming love for animals, I can't let them go without. One particular stray I ended up naming Edgar (Meowin Poe) had a severe case of ear mites and ticks were at an all time high. After months of warming up to this guy and finally earning his trust, my vet prescribed him Revolution Plus and it's been a game changer! It's a very small bottle, but packs a big punch! It's easy to open and the cap has a point to break the seal before applying. Behind one of Edgars ears, he had scratched raw and bloody and over a half dollar in size. In the first month of using it, the smaller scab on the other ear cleared up and hair grew back. The larger one had almost healed to half its size! I was able to take him to get neutered and had his ears flushed. Trying to clean the gunk out, was almost impossible with him. After 2.5 months of use, he is down to a dime size spot, with minimal scratching and all his hair has grown back. He's had no signs of ticks or fleas! I highly recommend this product to anyone who has fur babes that go outside, or in stray cases those who weren't given a choice but still deserve to be cared and looked after.

Rated 5 out of 5 stars
By Karen on Jan 20, 2026

Easy to apply

This is so simple to use every month. No prep required other than removing my cat's collar for a couple of days. No signs os skin irritation, and it has done a great

This is so simple to use every month. No prep required other than removing my cat's collar for a couple of days. No signs os skin irritation, and it has done a great job ant keeping fleas away. My vet recommended it highly, and I can see why.

Rated 5 out of 5 stars
By Leola on Jan 23, 2026

willing to send replacement for lost order

Even with no fault of Chewy. Now that the 899 home has delivered box, because it was in an unknown environment for almost 2 weeks, I do not plan to use the original

Even with no fault of Chewy. Now that the 899 home has delivered box, because it was in an unknown environment for almost 2 weeks, I do not plan to use the original order. Do you want it back or do I just discard?

Rated 5 out of 5 stars
By Carmen on Jan 26, 2026

Good coverage

Revolution plus offers good protection. The vial has a small amount and that makes it easier to apply. It works very well and offers good protection. I only need

Revolution plus offers good protection. The vial has a small amount and that makes it easier to apply. It works very well and offers good protection. I only need to apply it once every 6 months.

Rated 5 out of 5 stars
By Mariana on Jan 26, 2026

Vet approved!

Since we’ve had our cat, this is the only medication that he has been on. It’s easy to administer, and while he’s not a big fan of doing it, it’s kept him very healthy

Since we’ve had our cat, this is the only medication that he has been on. It’s easy to administer, and while he’s not a big fan of doing it, it’s kept him very healthy in the last 3 years!

Rated 5 out of 5 stars
By Vanessa on Dec 23, 2025

No irritation

Wow! I love this product. Other products usually leave a greasy spot where I apply it, but this one didn’t thank goodness. My cat was suffering from ear mites so

Wow! I love this product. Other products usually leave a greasy spot where I apply it, but this one didn’t thank goodness. My cat was suffering from ear mites so I got her treated and used this right after. Everything seems to be working fine by keeping fleas and the ear mites away.

Rated 3 out of 5 stars
By JUDITH on Nov 24, 2025

REvolution

I didn't care the way it came packaged outside of a box that I'm used to, with all the regulated information on it. It came as 6 different applications each in a

I didn't care the way it came packaged outside of a box that I'm used to, with all the regulated information on it. It came as 6 different applications each in a small Ziplock type bag. One, what a waste of plastic I think you could have fit all 6 in one small plastic bag. And again, not sure why they didn't come in the original box?? It looks like they were "left overs"

Rated 3 out of 5 stars
By Polly on Jan 17, 2026

The price

It is getting too expensive. To many animals suffer because their loved ones can afford this. I may have to consider a more cost effective but perhaps less effective

It is getting too expensive. To many animals suffer because their loved ones can afford this. I may have to consider a more cost effective but perhaps less effective alternative