Advantage II Flea Treatment for Dogs, 21-55 lbs, 6 Doses (6-mos. supply)
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About Advantage II for Dogs


Get the Advantage Over Fleas
Advantage II topical flea treatment and prevention for dogs kills fleas on your dog within 12 hours, and it continues to protect for 30 days. It’s easier to use than hard-to-swallow pills—simply apply the convenient drops once a month. Best of all, Advantage II is available without a prescription.
How Advantage II for Dogs Works
The active ingredients in Advantage II for Dogs (imidacloprid and pyriproxyfen) spread over the skin and hair coat. Fleas are killed through contact, so they don’t have to bite your dog to die. Do not use on cats.
Flea Treatment and Prevention
Advantage II doesn't just treat fleas––it breaks the flea lifecycle to prevent reinfestation.

Reliable Flea Protection
These flea drops kill adult fleas, flea larvae, flea eggs, and chewing lice.

Same-Day Effectiveness
Advantage II kills fleas on dogs within 12 hours, and it continues to prevent reinfestations for four weeks.

No Prescription Needed
You don’t have to go to the vet to get quality flea protection for your dog—simply buy and apply.

Fragrance-Free
This flea topical formula is fragrance-free and waterproof 24 hours after application.
Frequently Asked Questions
Can I Use Advantage II on My Dog?
Advantage II is for dogs 7 weeks of age and older. The product comes in four sizes: Small Dog (3-10 lbs.), Medium Dog (11-20 lbs.), Large Dog (21-55 lbs.), and Extra Large Dog (over 55 lbs.). Choose the right size based on your dog’s weight. Not for use on cats.

How Do I Apply Advantage II?
Break the seal on the tube, then part the hair on your dog’s back between the shoulder blades to show the skin. Squeeze the tube to expel the entire contents directly onto the skin. The number of application spots will depend on the weight of your dog—see product label for detailed instructions.
The Advantage Family
Get the Advantage over fleas with complete flea protection for your pet, home, and yard. The Advantage family of products has everything you need for a complete flea treatment and prevention plan, including monthly topical treatments, pet shampoos and sprays, household sprays for carpets and crevices, and even a yard and premise spray. Just be sure to get the right product for each need and use only as directed.

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