Prescription Topical Flea & Tick Treatment for Dogs

Keep biting pests off your dog with topical flea and tick medication. Chewy carries many types of prescription topical flea medicine, tick medicine, and non-prescription topical flea and tick products, too. Most topicals are designed to kill both fleas and ticks and to provide continuous protection over several weeks.

Before you buy prescription topical flea & tick medication online at Chewy, be sure to research your different flea control options and talk to your vet. The best flea & tick medication will be easy to administer, suited to your dog’s lifestyle, and effective for the climate you live in, and topicals can be a great choice. Your vet can advise you on whether a prescription topical product, an oral product or a non-prescription flea and tick treatment would be best for your dog. If you have a very young pup, you should talk to your veterinarian about prescription topical medicine for puppies and whether it might be a good choice for your furry friend.

If you choose a topical flea control medicine, using it is fairly easy: you simply apply the solution to the skin on the dog’s neck—choose a place where he can’t easily scratch or lick it off—and you’re done. Most prescription flea topicals for dogs offer long-lasting pest deterrence that can last for a month or more and they’re usually water-resistant, too.

Some pet parents like the convenience of oral flea and tick medication, especially the formulas that include heartworm medicine in one easy dose. Your vet can advise you on this and other prescription medications your pets may need. The Chewy pet pharmacy has most of the medicines your vet might prescribe for your pets, including flea & tick medication for cats, other prescription dog medicine, and medications for other types of pets as well. Shop our great selection of topical flea and tick medications and get everything you need to help your best friend live a healthy, pest-free life!

Frequently Asked Questions About Prescription Topical Flea & Tick Treatment for Dogs

How do I get dog topical flea and tick medication prescriptions online at Chewy Pharmacy?

Get dog topical flea and tick medication prescriptions online at Chewy Pharmacy by visiting your vet and talking about different flea and tick control options. Your vet can recommend a product and issue a prescription for the right type and dose. Then, go to and add the prescribed product to your cart. At checkout, add your dog’s info and vet contact information so Chewy can verify the prescription on your behalf. That’s all you need to do to order your prescription medications from Chewy!

What prescription dog topical flea and tick treatment is best?

The best prescription topical flea and tick treatment will vary by the age, health, lifestyle and habits of your pup, so talk to your vet about your choices. Popular brands include Advantage Multi, Revolution and Bravecto, but there are many others that may serve your situation well. You can read the customers reviews on our site to learn more about all the brands we carry.

What is the difference between over-the-counter and prescription dog topical flea and tick medication?

The difference between over-the-counter and prescription topical flea and tick medication is that you need a vet to prescribe the latter. The ingredients in prescription medications are more carefully controlled and regulated, and therefore, dosing may be more precise and possibly safer, too. Many prescription treatments are also more effective than over the counter products. Your vet can give you the most up-to-date information on what works well, what will be safest and which medication is right for your pup.

Where do I apply dog topical flea and tick medicine and what do I need to know?

Apply topical flea and tick medicine between the shoulder blades so your dog can’t lick or easily rub it off. Most topical medications provide protection for a month, not only killing fleas and ticks but repelling them, as well. Many are designed to break the flea lifecycle and prevent reinfestation by killing fleas at various stages of development. Some may also prevent flea and tick-borne diseases by killing pests before they can bite your dog. Read up on the different products available and consult with your vet about which options are right for you.

How do I set up Autoship for my prescription dog topical flea and tick medicine?

To set up Autoship for your prescription dog topical flea and tick medicine, select the Autoship option at checkout and choose a delivery frequency. Once you set up Autoship, you can change or cancel it any time you want. You must have a valid prescription or remaining refills on file for Autoship pharmacy deliveries to occur. If we do not have a prescription, or if your prescription is expiring soon, one of our team members will reach out to your vet to obtain all the necessary information. You never have to run out of your dog’s prescription topical flea and tick medicine again with Autoship from Chewy!