Prescription Flea & Tick Medicine for Dogs

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NexGard Chew for Dogs, 24.1-60 lbs, (Purple Box), 3 Chews (3-mos. supply)

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Rated 4.6507 out of 5 stars
753Reviews
$62.99Chewy Price
$64.00List Price
$59.84Autoship Price

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NexGard Chew for Dogs, 60.1-121 lbs, (Red Box), 3 Chews (3-mos. supply)

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Rated 4.7239 out of 5 stars
757Reviews
$62.99Chewy Price
$66.00List Price
$59.84Autoship Price

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NexGard Chew for Dogs, 10.1-24 lbs, (Blue Box), 3 Chews (3-mos. supply)

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Rated 4.7641 out of 5 stars
674Reviews
$62.99Chewy Price
$59.84Autoship Price

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Bravecto Chew for Dogs, 44-88 lbs, (Blue Box), 1 Chew (12-wks. supply)

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Rated 4.5603 out of 5 stars
605Reviews
$59.99Chewy Price

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Bravecto Chew for Dogs, 9.9-22 lbs, (Orange Box), 1 Chew (12-wks. supply)

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Rated 4.7547 out of 5 stars
322Reviews
$58.49Chewy Price

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Simparica Trio Chewable Tablet for Dogs, 22.1-44.0 lbs, (Teal Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5357 out of 5 stars
84Reviews
$163.53Chewy Price
$155.35Autoship Price

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Simparica Chewable Tablet for Dogs, 44.1-88 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6028 out of 5 stars
287Reviews
$110.98Chewy Price
$105.43Autoship Price

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NexGard Chew for Dogs, 4-10 lbs, (Orange Box), 3 Chews (3-mos. supply)

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Rated 4.6814 out of 5 stars
204Reviews
$62.99Chewy Price
$59.84Autoship Price

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Bravecto Chew for Dogs, 22-44 lbs, (Green Box), 1 Chew (12-wks. supply)

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Rated 4.5357 out of 5 stars
252Reviews
$59.49Chewy Price

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Trifexis Chewable Tablet for Dogs, 60.1-120 lbs, (Brown Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6126 out of 5 stars
222Reviews
$127.49Chewy Price
$121.12Autoship Price

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Credelio Chewable Tablet for Dogs, 50.1-100 lbs, (Blue Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6721 out of 5 stars
61Reviews
$113.80Chewy Price
$108.11Autoship Price

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Sentinel Tablet for Dogs, 11-25 lbs, (Green Box), 6 Tablets (6-mos. supply)

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Rated 4.4038 out of 5 stars
156Reviews
$50.49Chewy Price

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Bravecto Chew for Dogs, 88-123 lbs, (Pink Box), 1 Chew (12-wks. supply)

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Rated 4.5828 out of 5 stars
151Reviews
$60.49Chewy Price

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Simparica Chewable Tablet for Dogs, 11.1-22 lbs, (Orange Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6815 out of 5 stars
157Reviews
$99.67Chewy Price
$94.69Autoship Price

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Simparica Trio Chewable Tablet for Dogs, 5.6-11.0 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6984 out of 5 stars
63Reviews
$148.34Chewy Price
$140.92Autoship Price

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Credelio Chewable Tablet for Dogs, 12.1-25 lbs, (Orange Box), 1 Chewable Tablet (1-mo. supply)

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Rated 4.2034 out of 5 stars
59Reviews
$20.59Chewy Price
$19.56Autoship Price

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Trifexis Chewable Tablet for Dogs, 10.1-20 lbs, (Orange Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6087 out of 5 stars
276Reviews
$119.99Chewy Price
$113.99Autoship Price

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Bravecto Chew for Dogs, 4.4-9.9 lbs, (Yellow Box), 1 Chew (12-wks. supply)

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Rated 4.6848 out of 5 stars
92Reviews
$56.99Chewy Price

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Credelio Chewable Tablet for Dogs, 25.1-50 lbs, (Green Box), 1 Chewable Tablet (1-mo. supply)

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Rated 4.22 out of 5 stars
50Reviews
$22.65Chewy Price
$21.52Autoship Price

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Simparica Chewable Tablet for Dogs, 22.1-44 lbs, (Mint Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.7311 out of 5 stars
119Reviews
$107.88Chewy Price
$102.49Autoship Price

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Revolution Topical Solution for Dogs, 20.1-40 lbs, (Red Box), 6 Doses (6-mos. supply)

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Rated 4.7812 out of 5 stars
64Reviews
$137.99Chewy Price
$131.09Autoship Price

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Sentinel Tablet for Dogs, 26-50 lbs, (Yellow Box), 6 Tablets (6-mos. supply)

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Rated 4.5652 out of 5 stars
115Reviews
$59.99Chewy Price

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Trifexis Chewable Tablet for Dogs, 40.1-60 lbs, (Blue Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5398 out of 5 stars
176Reviews
$125.49Chewy Price
$119.22Autoship Price

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Sentinel Tablet for Dogs, 51-100 lbs, (White Box), 6 Tablets (6-mos. supply)

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Rated 4.6778 out of 5 stars
180Reviews
$72.49Chewy Price

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Simparica Chewable Tablet for Dogs, 88.1-132 lbs, (Brown Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.4082 out of 5 stars
49Reviews
$112.53Chewy Price
$106.90Autoship Price

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Advantage Multi Topical Solution for Dogs, 55.1-88 lbs, (Blue Box), 6 Doses (6-mos. supply)

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Rated 4.7143 out of 5 stars
63Reviews
$115.99Chewy Price
$127.74List Price
$110.19Autoship Price

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Credelio Chewable Tablet for Dogs, 6.1-12 lbs, (Pink Box), 1 Chewable Tablet (1-mo. supply)

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Rated 4.5588 out of 5 stars
34Reviews
$20.59Chewy Price
$19.56Autoship Price

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Trifexis Chewable Tablet for Dogs, 20.1-40 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5879 out of 5 stars
182Reviews
$122.99Chewy Price
$116.84Autoship Price

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Bravecto 1-Month Chew for Dogs, 44-88 lbs, (Blue Box), 1 Chew (1-mo. supply)
Rated 3.5 out of 5 stars
4Reviews
$20.49Chewy Price

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Simparica Chewable Tablet for Dogs, 5.6-11 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6765 out of 5 stars
68Reviews
$97.73Chewy Price
$92.84Autoship Price

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Bravecto Topical Solution for Dogs, 9.9-22 lbs, (Orange Box), 1 Dose (12-wks. supply)

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Rated 4.069 out of 5 stars
29Reviews
$51.49Chewy Price

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Senergy Topical Solution for Dogs, 40.1-85 lbs, (Teal Box), 3 Doses (3-mos. supply)
Rated 5 out of 5 stars
2Reviews
$46.13Chewy Price
$43.82Autoship Price

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Bravecto 1-Month Chew for Dogs, 22-44 lbs, (Green Box), 1 Chew (1-mo. supply)
Rated 5 out of 5 stars
3Reviews
$19.99Chewy Price

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Sentinel Spectrum Chew for Dogs, 8.1-25 lbs, (Green Box), 6 Chews (6-mos. supply)

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Rated 4.5784 out of 5 stars
102Reviews
$52.99Chewy Price

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Trifexis Chewable Tablet for Dogs, 5-10 lbs, (Magenta Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5833 out of 5 stars
96Reviews
$113.99Chewy Price
$108.29Autoship Price

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Bravecto 1-Month Chew for Dogs, 9.9-22 lbs, (Orange Box), 1 Chew (1-mo. supply)
$19.49Chewy Price

FREE shipping over $49

  • Prescription Item

Prescription Flea & Tick Medicine for Dogs

Keep biting pests from plaguing your pup with a prescription flea and tick medication. Chewy carries several types of prescription flea and tick treatment, including topical and oral flea & tick medication, as well as combination medications that prevent heartworms and kill common parasites, too.

Before you buy prescription flea & tick medication online, be sure to research all your options. The best flea and tick medicine will be easy to administer, suited to your dog’s lifestyle and effective for the climate you live in. Your vet can advise you on whether you need prescription flea and tick pills, a prescription topical product, or a non-prescription flea and tick treatment. If you have a younger dog, you should talk to your veterinarian about prescription flea & tick medicine for puppies and whether it would be a good choice for your furry friend.

Prescription flea and tick topical treatments are easy to apply and can provide continuous protection that lasts a month or more. Many are also water-resistant, so they won’t interfere with regular bathing and grooming. Several prescription flea pills can offer long-lasting pest deterrence that’s water-friendly, too. Other flea control options include flea shampoos that let you wash annoying pests away, dog flea and tick sprays that kill on contact and yard treatment sprays that get to fleas before they can jump on your pup.

You can also choose combination products that combine heartworm medicine with prescription oral flea and tick medication in one dose. The Chewy pet pharmacy has many of the medications your vet might prescribe for your pets, including flea & tick medication for cats and other prescription dog medicine for a variety of ailments. Shop our great selection of prescription flea and tick medications and get everything you need to help your best friend live an itch-free life!

Frequently Asked Questions about Prescription Flea & Tick Medicine for Dogs

How do I get dog flea and tick medication prescriptions online at Chewy Pharmacy?

Get dog flea and tick medication prescriptions online at Chewy Pharmacy by visiting your vet and talking about flea and tick control options. Your vet can then write you a prescription for the product and dose what’s appropriate for your pup. Then, go online and add the prescribed product to your cart. At checkout, you can add your dog’s info and vet contact information so Chewy can verify the prescription on your behalf. That’s all you need to do to order your prescription medications from Chewy!

What prescription dog flea and tick treatment is best?

The best prescription flea and tick treatment will vary by the age, health, lifestyle and habits of your dog and can best be determined by your vet. Popular brands include Comfortis, Advantage Multi, Simparica Trio, Revolution and Credelio, but there are many others that may uniquely suit your situation. Many come as once-a-month topicals or chewable tablet doses for easy use. Check out some of the great reviews on our site to learn more about which ones might be best for your bestie!

What is the difference between over-the-counter and prescription dog flea and tick medication?

The difference between over-the-counter and prescription flea and tick medication is that you need a vet to prescribe the latter. The ingredients in prescription medications are more carefully controlled and regulated, and therefore, dosing may be more precise and possibly safer. Many prescription treatments are more effective than over the counter products, as well. Your vet can give you the most up-to-date information on what works well, what’s safest and what’s right for your pup.

How do dog flea treatments work?

Dog flea treatments work in different ways depending on which product you use. Prescription oral and topical flea treatments usually work by depositing chemicals into the sebaceous glands of your dog. These chemicals then spread out over the body as your dog’s coat lubricates itself, neutralizing fleas and ticks by acting on their central nervous system. This prevents them from feeding on your pup and causing irritation, itch, parasites and disease.

How do I set up Autoship for my prescription dog medicine?

To set up Autoship for your prescription dog medicine, select the Autoship option at checkout and choose how often you want it delivered. Once you set up Autoship, you can cancel or change your deliveries any time you want. You must have a valid prescription or remaining refills on file for Autoship pharmacy deliveries to occur. If we do not have a prescription, or if your prescription is expiring soon, one of our team members will reach out to your vet to obtain all the necessary information. You’ll always have your prescription dog medicines on hand when you choose Autoship from Chewy!