Prescription Heartworm Prevention Medicine for Dogs

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Heartgard Plus Chew for Dogs, 51-100 lbs, (Brown Box), 6 Chews (6-mos. supply)

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Rated 4.9186 out of 5 stars
1105Reviews
$59.99Chewy Price
$56.99Autoship Price

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Heartgard Plus Chew for Dogs, up to 25 lbs, (Blue Box), 6 Chews (6-mos. supply)

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Rated 4.9353 out of 5 stars
1020Reviews
$39.99Chewy Price
$40.00List Price
$37.99Autoship Price

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Heartgard Plus Chew for Dogs, 26-50 lbs, (Green Box), 6 Chews (6-mos. supply)

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Rated 4.9431 out of 5 stars
598Reviews
$49.99Chewy Price
$47.49Autoship Price

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Interceptor Plus Chew for Dogs, 50.1-100 lbs, (Blue Box), 6 Chews (6-mos. supply)

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Rated 4.6701 out of 5 stars
391Reviews
$58.75Chewy Price
$55.81Autoship Price

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Tri-Heart Plus Chewable Tablet for Dogs, up to 25 lbs, (Blue Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6906 out of 5 stars
223Reviews
$21.99Chewy Price
$29.30List Price

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Sentinel Tablet for Dogs, 26-50 lbs, (Yellow Box), 6 Tablets (6-mos. supply)

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Rated 4.5614 out of 5 stars
114Reviews
$59.99Chewy Price

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Interceptor Plus Chew for Dogs, 25.1-50 lbs, (Yellow Box), 6 Chews (6-mos. supply)

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Rated 4.6853 out of 5 stars
197Reviews
$48.35Chewy Price
$45.93Autoship Price

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Tri-Heart Plus Chewable Tablet for Dogs, 51-100 lbs, (Brown Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.7811 out of 5 stars
265Reviews
$37.99Chewy Price
$51.10List Price

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Interceptor Plus Chew for Dogs, 8.1-25 lbs, (Green Box), 6 Chews (6-mos. supply)

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Rated 4.722 out of 5 stars
241Reviews
$42.11Chewy Price
$40.00Autoship Price

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Trifexis Chewable Tablet for Dogs, 60.1-120 lbs, (Brown Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6126 out of 5 stars
222Reviews
$127.49Chewy Price
$121.12Autoship Price

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Sentinel Tablet for Dogs, 51-100 lbs, (White Box), 6 Tablets (6-mos. supply)

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Rated 4.6778 out of 5 stars
180Reviews
$72.49Chewy Price

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Tri-Heart Plus Chewable Tablet for Dogs, 26-50 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.694 out of 5 stars
134Reviews
$28.99Chewy Price
$39.30List Price

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Simparica Trio Chewable Tablet for Dogs, 11.1-22.0 lbs, (Caramel Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5567 out of 5 stars
97Reviews
$150.97Chewy Price
$143.42Autoship Price

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Sentinel Tablet for Dogs, 11-25 lbs, (Green Box), 6 Tablets (6-mos. supply)

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Rated 4.4038 out of 5 stars
156Reviews
$50.49Chewy Price

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Simparica Trio Chewable Tablet for Dogs, 22.1-44.0 lbs, (Teal Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5357 out of 5 stars
84Reviews
$163.53Chewy Price
$155.35Autoship Price

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Sentinel Spectrum Chew for Dogs, 50.1-100 lbs, (Blue Box), 6 Chews (6-mos. supply)

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Rated 4.2202 out of 5 stars
109Reviews
$77.49Chewy Price

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Trifexis Chewable Tablet for Dogs, 10.1-20 lbs, (Orange Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6087 out of 5 stars
276Reviews
$119.99Chewy Price
$113.99Autoship Price

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Interceptor Chewable Tablet for Dogs, 51-100 lbs, & Cats, 12.1-25 lbs, (White Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.75 out of 5 stars
40Reviews
$60.31Chewy Price
$57.29Autoship Price

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Advantage Multi Topical Solution for Dogs, 55.1-88 lbs, (Blue Box), 6 Doses (6-mos. supply)

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Rated 4.7143 out of 5 stars
63Reviews
$115.99Chewy Price
$127.74List Price
$110.19Autoship Price

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Interceptor Plus Chew for Dogs, 2-8 lbs, (Orange Box), 6 Chews (6-mos. supply)

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Rated 4.4 out of 5 stars
50Reviews
$41.07Chewy Price
$39.02Autoship Price

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Sentinel Spectrum Chew for Dogs, 8.1-25 lbs, (Green Box), 6 Chews (6-mos. supply)

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Rated 4.5784 out of 5 stars
102Reviews
$52.99Chewy Price

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Trifexis Chewable Tablet for Dogs, 40.1-60 lbs, (Blue Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5398 out of 5 stars
176Reviews
$125.49Chewy Price
$119.22Autoship Price

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Iverhart Plus Chewable Tablet for Dogs, 1-25 lbs, (Blue Box), 6 Chewable Tablets (6-mos. supply)
Rated 4.7241 out of 5 stars
29Reviews
$25.86Chewy Price
$24.57Autoship Price

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Simparica Trio Chewable Tablet for Dogs, 5.6-11.0 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.6984 out of 5 stars
63Reviews
$148.34Chewy Price
$140.92Autoship Price

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Sentinel Tablet for Dogs, 2-10 lbs, (Brown Box), 6 Tablets (6-mos. supply)

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Rated 4.7812 out of 5 stars
64Reviews
$47.99Chewy Price
$49.00List Price

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Revolution Topical Solution for Dogs, 20.1-40 lbs, (Red Box), 6 Doses (6-mos. supply)

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Rated 4.7812 out of 5 stars
64Reviews
$137.99Chewy Price
$131.09Autoship Price

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Iverhart Plus Chewable Tablet for Dogs, 51-100 lbs, (Brown Box), 6 Chewable Tablets (6-mos. supply)
Rated 4.8182 out of 5 stars
22Reviews
$44.93Chewy Price
$42.68Autoship Price

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Trifexis Chewable Tablet for Dogs, 20.1-40 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5879 out of 5 stars
182Reviews
$122.99Chewy Price
$116.84Autoship Price

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Sentinel Spectrum Chew for Dogs, 25.1-50 lbs, (Yellow Box), 6 Chews (6-mos. supply)

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Rated 4.6038 out of 5 stars
53Reviews
$64.49Chewy Price

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Advantage Multi Topical Solution for Dogs, 9.1-20 lbs, (Teal Box), 6 Doses (6-mos. supply)

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Rated 4.7119 out of 5 stars
59Reviews
$115.99Chewy Price
$127.74List Price
$110.19Autoship Price

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Interceptor Chewable Tablet for Dogs, 11-25 lbs, & Cats, 1.5-6 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)
Rated 4.6667 out of 5 stars
27Reviews
$42.63Chewy Price
$40.50Autoship Price

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Trifexis Chewable Tablet for Dogs, 5-10 lbs, (Magenta Box), 6 Chewable Tablets (6-mos. supply)

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Rated 4.5833 out of 5 stars
96Reviews
$113.99Chewy Price
$108.29Autoship Price

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Iverhart Plus Chewable Tablet for Dogs, 26-50 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)
Rated 4.6316 out of 5 stars
19Reviews
$34.65Chewy Price
$32.92Autoship Price

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Milbehart Flavored Tablets for Dogs, 51-100 lbs, & Cats, 12-25 lbs, (Gray Box), 6 Flavored Tablets (6-mos. supply)
$45.28Chewy Price
$43.02Autoship Price

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Advantage Multi Topical Solution for Dogs, 3-9 lbs, (Green Box), 6 Doses (6-mos. supply)

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Rated 4.4615 out of 5 stars
26Reviews
$115.99Chewy Price
$127.74List Price
$110.19Autoship Price

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Iverhart Max Chew for Dogs, 50.1-100 lbs, (Brown Box), 6 Chews (6-mos. supply)
Rated 3.4286 out of 5 stars
28Reviews
$51.39Chewy Price
$48.82Autoship Price

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Try Iverhart MAX or Senergy for Heartworm protection today!


Prescription Heartworm Prevention Medicine for Dogs

Protect your dog against the scourge of heartworms with preventative heartworm medicine. Chewy carries many types of heartworm medication for dogs, including heartworm pills, topical heartworm medications, and combination products that kill other parasites too.

Your vet is the person to ask about the best heartworm prevention for dogs. Your vet should be up to date on all the latest products available and can advise you on which ones may be best for your pup. For owners of younger dogs, it is important to ask about heartworm medicine for puppies, as younger pups need protection as well. Heartworm medication is available only by prescription, and your vet will need to perform a heartworm test before prescribing any preventatives. If your dog tests positive for heartworms, he will need to undergo heartworm treatment to eliminate the dangerous parasites.

Once your dog has tested negative for heartworms or completed heartworm treatment, he can begin the heartworm preventative regimen recommended and prescribed by his vet. You should have the option of choosing between oral heartworm medications in pill, chewable tablet or soft chew form or a heartworm preventative medicine applied as a topical. Most heartworm medicines provide protection for up to a month, and some are available as combo treatments that protect against roundworms, hookworms, tapeworms and more.

You can also choose combination products that combine heartworm medicine with prescription flea & tick medication in one easy dose for convenience. There are many options for heartworm protection and choosing the right one is important. The Chewy pet pharmacy has many medications needed to keep your pets healthy and safe, including prescription dog medicine for a variety of ailments, flea & tick medication for cats and medications for your other pets too. Shop our wide selection of heartworm medicine so you can protect your best friend 24/7.

Frequently Asked Questions about Prescription Heartworm Prevention Medicine for Dogs

How do I get dog heartworm medicine prescriptions online at Chewy Pharmacy?

Get dog heartworm medicine prescriptions online at Chewy Pharmacy by visiting your vet and talking about the different options. Your vet can perform a heartworm test, recommend a product and issue a prescription for the right preventative and dose. Then, go to Chewy.com and add the prescribed product to your cart. At checkout, you can add your dog’s info and vet contact information so Chewy can verify the prescription. That’s all you need to do to order your heartworm medications from Chewy!

What prescription dog heartworm medicine is best?

The best prescription heartworm medicine will provide year-round protection in an easy-to-administer formula. Your vet can advise you on the different options available and issue a prescription you can use to order your medicine online. Discuss whether you want just heartworm prevention or a combination product that includes dewormers, flea and tick protection, or all three in one dose. Popular brands include Heartgard, Tri-Heart Plus, Sentinel, Revolution and Interceptor Plus.

Why is dog heartworm medicine only available with a prescription?

Dog heartworm medicine is only available with a prescription because your dog needs a heartworm test to ensure he isn’t already infected first. Giving a heartworm preventative to a dog who is already infected can be dangerous or even deadly. A vet can also determine the right dosage for your pet and suggest the right products for your dog’s lifestyle, health and age.

Do dogs need heartworm medicine in the winter?

Dogs need heartworm medicine in the winter, spring, fall and summer because the danger of failing to protect them is too great. Although there are fewer mosquitos around during winter in most climates, there is still the risk of a bite and heartworm contraction. Protect your best friend year-round from heartworms for safety and peace of mind.

How do I set up Autoship for my prescription dog heartworm medicine?

Set up Autoship for your prescription dog heartworm medicine by selecting the Autoship option and choosing a delivery frequency at checkout. Once you set up Autoship, you can change or cancel it any time you want. You must have a valid prescription or remaining refills on file for Autoship pharmacy deliveries to occur. If we do not have a prescription, or if your prescription is expiring soon, one of our team members will reach out to your vet to obtain all the necessary information. You can always have your dog’s heartworm medicine on hand with Autoship from Chewy!