Heartgard Plus Chew for Dogs, 51-100 lbs, (Brown Box)

By Heartgard
Rated 4.9105 out of 5 stars
Prescription Item
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Heartgard Plus Chew for Dogs, 51-100 lbs, (Brown Box), 6 Chews (6-mos. supply) slide 1 of 11
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Heartgard Plus Chew for Dogs, 51-100 lbs, (Brown Box), 6 Chews (6-mos. supply) slide 1 of 11

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$63.99Chewy Price
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Frequently Bought Together

Frequently Bought Together
Rated 4.9105 out of 5 stars
$63.99Chewy Price

Bundle Heartgard Plus with NexGard and Save 15% Off at Checkout With Code: HGNG15

Frequently Bought Together
Rated 4.7114 out of 5 stars
$125.99Chewy Price

Bundle Heartgard Plus with NexGard and Save 15% Off at Checkout With Code: HGNG15

Frequently Bought Together
Rated 4.6527 out of 5 stars
$125.99Chewy Price

Bundle Heartgard Plus with NexGard and Save 15% Off at Checkout With Code: HGNG15

Total Price: $0.00

About This Item

For use in animals only. Heartgard Plus Chew for Dogs, 51-100 lbs. is a heartworm preventative that kills heartworms and also helps treat and control roundworms and hookworms. It comes in a delicious once-a-month, real-beef chew that dogs love and is safe for puppies 6 weeks and older. Head back to the dog park, reassured that your dog is protected from nasty parasites with this heartworm preventative that's trusted over 2 billion times! Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

Play Video: Learn More About Heartgard From Our Team of Experts
Learn More About Heartgard From Our Team of Experts

Dosage Chart

Color on BoxWeight RangeStrengthDosageProduct Page
BlueUp to 25 lbs68 mcg Ivermectin & 57 mg PyrantelAdministered orally at monthly intervals✓-Click Here
Green26 to 50 lbs136 mcg Ivermectin & 114 mg PyrantelAdministered orally at monthly intervals✓-Click Here
Brown51 to 100 lbs272 mcg Ivermectin & 227 mg PyrantelAdministered orally at monthly intervals✓-Click Here

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About HEARTGARD Plus Soft Chews

Protection Dogs Love

HEARTGARD Plus (ivermectin/pyrantel) prevents the invisible and potentially deadly threat of heartworm disease. HEARTGARD Plus not only prevents heartworm disease, but it also treats and controls 3 species of hookworms and 2 species of roundworms. Plus, it comes as a real-beef chew with a taste dogs love.

Recommended by Vets

Whether for their patients or their own dogs, HEARTGARD Plus is recommended by vets. Safe for puppies as young as 6 weeks of age with no minimum weight requirement, HEARTGARD Plus delivers safe but powerful protection against heartworm disease. Trusted over 2 billion times, with HEARTGARD Plus, you can rest easy knowing your dog is protected.

Dogs Love Real-Beef Chews

Preventing heartworm disease never tasted so good! So, forget wrapping pills in sliced cheese, and put away the peanut butter. Giving real-beef HEARTGARD Plus chewables is easy because dogs love the taste, making monthly dosing an enjoyable experience.

All Dogs Are at Risk Year-Round

Inside or out, year-round, all dogs are at risk for heartworm disease no matter where you live in the US. When it comes to heartworm disease, treatment can be expensive, traumatic, and is not always effective. Instead, protect your dog every month with delicious HEARTGARD Plus.

Product Guide

HEARTGARD Plus offers protection for dogs in most sizes and weights. Choose the option best fitted for your pet.

Up to 25 lbs

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26 - 50 lbs

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51 - 100 lbs

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HEARTGARD Plus (ivermectin/pyrantel) is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian, or refer to the full prescribing information.


Data on file at Boehringer Ingelheim. HEARTGARD® Plus (ivermectin/pyrantel) Chewables [Freedom of Information Summary; NADA 140-971]. Duluth, GA: Boehringer Ingelheim Animal Health USA Inc. Prevent Heartworms in Dogs, Cats, and Ferrets Year-Round _FDA Consumer Updateshttps://www.fda.gov/consumers/consumer-updates/preventheartworms-dogs-cats-andferrets-yearround#:~:text=That’s%20one%20reason%20veterinarians%2often,giving%20medication%20during%20this%20season. Accessed 2/8/2021.


HEARTGARD Plus is a monthly, real-beef chewable that prevents heartworm disease and treats and controls hookworms and roundworms. As a vet-recommended heartworm disease prevention, HEARTGARD Plus is safe for all breeds and sizes of dogs, you can begin protecting your puppy as young as six weeks of age. The great taste makes monthly dosing a delight. Ask your veterinarian about preventing heartworm disease in your dog with HEARTGARD Plus.

ReviewsWrite a Review

Rated 4.9105 out of 5 stars
1185 Reviews
Would recommend to a friend

1185 Customer Reviews

Rated 5 out of 5 stars
By Dani on May 7, 2022

An essential medication

Many years ago when heartworm first started killing dogs on the East Coast (where I lived then), I lost a marvelous German Shepherd to this awful disease. That's why I've been a loyal customer for Heartgard since those early days. The "Plus" version is new to me, but I'm sure it's excellent too. And I appreciate the Chewy pharmacy people who have explained it to me. They're the best!

Rated 5 out of 5 stars
By ShadowsMommy on May 3, 2022

Only Heart worm meds we buy!

I’ve been giving these to my black lab since he was a puppy, (he is almost 4 now) he loves the taste of them and gets upset because I only give him 1 chew. He thinks they’re a treat! They work great and never had a problem with them. Definitely recommend.

Rated 5 out of 5 stars
By SkubaKat on Apr 5, 2022

Been using it for years! Highly recommend!

I've been buying this HW Med for years for our different dogs, and cats over the years since 1992. We bought it regularly from our local vets over the years. Then, we found it here. We keep buying this regularly because for us with regular scheduled use since 1992, none of our pets, dog or cats have come down with Heartworm, and fingers crossed they never do. NOTE: It must be given without fail on a regular schedule every 30 days. If you forget, you chance your pet getting Heartworm. We live in the Deep South were mosquitoes are a nuisance year long and we still give it regularly. Highly, highly recommend....Love the quick shipping Chewy provides, too! Thanks!

Rated 5 out of 5 stars
By Trumpy on May 14, 2022

Great people

My Mommy is pulse like to thank everyone at Chewy for taking such good care of me. She feels so much better knowing that I have my heart worm pills on time all the time!!!!!

Rated 5 out of 5 stars
By Kujo on Apr 11, 2022

My dog lives Heartguard

Some of the other heart worm treatments made our dog, Kujo, sick and it was so hard to pill her. With Heartguard she eats it without a struggle. Chewy makes it effortless. They contact the vet and we receive the meds in no time. Thank you Cheey!

Rated 5 out of 5 stars
By DDBFarm on Apr 3, 2022

Grateful in Riverview, FL

Running a small homestead isn't cheap and I greatly appreciate the discounts at Chewy for all my pet & livestock health. My veterinarian cooperates graciously with Chewy to make these savings easy for me. In regards to the Heartgard Plus, specifically, my vet assures me this product is safe for my dogs and they respond to them like treats.

Rated 5 out of 5 stars
By Skyefall on Apr 7, 2022

Heartgard does the job

Rx Are always filled promptly. Our vet is contacted as necessary and the prescription arrives within a day or two. Always pleased with Chewy’s service And heart guard keeps our pets well protected here in the south where mosquitoes run rampant

Rated 4 out of 5 stars
By Lokimrrogers on May 11, 2022

Good service

Timely delivery, and courteous staff .. very pleased with Chewy. Thanks for helping me with my dog's heartworm prevention. Very easy experience!

Rated 5 out of 5 stars
By Ward on Apr 24, 2022

In Stock With Chewy

So happy to see you continue to carry this particular name brand of heartworm medication. Our vet stopped carrying it and I was thrilled to see you have it in stock to order!

Rated 5 out of 5 stars
By Millie on Apr 29, 2022

Heart guard chews

Used it for my last dog and loved it, so it followed that I would use it for my new puppy, Finn. And Finn doesn't like anything but he ate the chew - no problem.