10 Best Puppy Milk Replacers 2026: According to Reviews | Chewy

The 10 Best Puppy Milk Replacers

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Best Puppy Milk Replacers
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How we created this puppy milk replacer list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best puppy milk replacer.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best puppy milk replacers.

Key puppy milk replacer considerations

Digestibility

Ease of Preparation

Nutritional Content

Palatability

1
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can
PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can

PetAg Esbilac Puppy Milk Replacer Powder for Puppies, 28-oz can

Rated 4.7 out of 5 stars
367
$61.37 Chewy Price
($2.20/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.7/5
Excellent

Ease of Preparation

4.6/5
Excellent

Nutritional Content

4.5/5
Great

Palatability

4.3/5
Great

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Puppy

Top Ingredients

Vegetable Oil (With Tocopherols And Ascorbyl Palmitate (Preservatives), Rosemary Extract), Casein, Dried Whey Protein Concentrate, Maltodextrins

Special Diet

High Fat
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2
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count
Four Paws Pet Nurser Bottles, 2-oz, 2 count

Four Paws Pet Nurser Bottles, 2-oz, 2 count

Rated 4.3 out of 5 stars
256
$6.49 Chewy Price
($1.63/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Digestibility

3.8/5
Good

Ease of Preparation

4.2/5
Great

Nutritional Content

4.3/5
Great

Palatability

4.3/5
Great

Is this puppy milk replacer right for my pet?

Breed Size

Extra Small Breeds, Small Breeds

Lifestage

Nursing

Health Feature

First Aid
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3
PetAg Esbilac 2nd Step Puppy Weaning Food, 14-oz can
PetAg Esbilac 2nd Step Puppy Weaning Food, 14-oz can
PetAg Esbilac 2nd Step Puppy Weaning Food, 14-oz can
PetAg Esbilac 2nd Step Puppy Weaning Food, 14-oz can
PetAg Esbilac 2nd Step Puppy Weaning Food, 14-oz can

PetAg Esbilac 2nd Step Puppy Weaning Food, 14-oz can

Rated 4.5 out of 5 stars
175
$16.49 Chewy Price
($1.18/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.8/5
Excellent

Ease of Preparation

4.6/5
Excellent

Nutritional Content

4.6/5
Excellent

Palatability

4.6/5
Excellent

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Puppy

Top Ingredients

Rice Flour, Dried Skimmed Milk, Dried Meat Solubles, Animal Fat (Preserved With Bha And Bht), Dried Whey Protein Concentrate

Special Diet

High-Protein
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4
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can
PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can

PetAg Goat's Milk Esbilac Puppy Milk Replacer Powder for Puppies, 12-oz can

Rated 4.6 out of 5 stars
251
$28.70 Chewy Price
($2.40/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.4/5
Great

Ease of Preparation

4.5/5
Great

Nutritional Content

4.3/5
Great

Palatability

4.5/5
Great

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Puppy

Top Ingredients

Vegetable Oil (With Tocopherols And Ascorbyl Palmitate (Preservatives), Rosemary Extract), Dried Whole Goat Milk Powder, Casein, Dried Whey Protein Concentrate

Special Diet

High Fat
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5
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can
PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can

PetAg PetLac Puppy Milk Replacement Powder for Puppies, 10.5-oz can

Rated 4.8 out of 5 stars
99
$17.84 Chewy Price
($1.70/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.7/5
Excellent

Ease of Preparation

4.6/5
Excellent

Nutritional Content

4.6/5
Excellent

Palatability

4.8/5
Excellent

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Puppy

Top Ingredients

Dried Skimmed Milk, Vegetable Oil (Preserved With Tocopherols), Soy Protein Isolate, Animal Fat (Preserved With Bha And Bht), Casein

Food Flavor

Unflavored
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6
PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz
PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz
PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz
PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz
PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz
PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz

PetAg Esbilac Puppy Milk Replacer Liquid Supplement, 16-fl oz

Rated 4.8 out of 5 stars
26
$14.02 Chewy Price
($0.88/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.6/5
Excellent

Ease of Preparation

4.7/5
Excellent

Nutritional Content

4.6/5
Excellent

Palatability

4.6/5
Excellent

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Puppy

Top Ingredients

Water, dried whole milk, casein, soybean oil (preserved with mixed tocopherols and ascorbyl palmitate), dicalcium phosphate

Packaging Type

Bottle
View Item Details
7
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag
Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag

Zesty Paws Milk Replacement Supplement Powder for Puppies & Senior Dogs, 12-oz bag

Rated 4.3 out of 5 stars
32
$34.97 Chewy Price
($2.92/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Digestibility

4.4/5
Great

Ease of Preparation

4.7/5
Excellent

Nutritional Content

4.5/5
Great

Palatability

4.1/5
Great

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Senior

Top Ingredients

Cream, Coconut Oil, Whey Protein Concentrate, Sodium Caseinate, Colostrum (Bovine)

Packaging Type

Bag
View Item Details
8
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar
Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar

Vets Preferred Advanced Milk Rx Dog Supplement, 12-oz jar

Rated 4.7 out of 5 stars
27
$27.97 Chewy Price
($2.34/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Digestibility

4.6/5
Excellent

Ease of Preparation

4.7/5
Excellent

Nutritional Content

4.6/5
Excellent

Palatability

4.4/5
Great

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Animal & Vegetable Fat (Preserved With Bha And Bht, Dried Whey Protein Concentrate, Dried Whey, Sodium Casinate, Dicalcium Phosphate

Special Diet

High-Protein
View Item Details
9
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz
Nutri-Vet Powder Milk Supplement for Dogs, 12-oz

Nutri-Vet Powder Milk Supplement for Dogs, 12-oz

Rated 4.8 out of 5 stars
23
$26.18 Chewy Price
($2.19/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.7/5
Excellent

Ease of Preparation

4.7/5
Excellent

Nutritional Content

4.3/5
Great

Palatability

4.7/5
Excellent

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Animal & Vegetable Fat (Preserved With Bha And Bht), Dried Whey Protein Concentrate, Dried Whey, Dried Whey Product, Dicalcium Phosphate

Packaging Type

Tub
View Item Details
10
PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can
PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can
PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can
PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can
PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can
PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can

PetAg Esbilac Healthy Aging Skin & Coat Supplement Dog Powder, 14-oz can

Rated 4 out of 5 stars
21
$13.13 Chewy Price
($0.94/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Digestibility

4.3/5
Great

Ease of Preparation

4.1/5
Great

Nutritional Content

4.1/5
Great

Palatability

4.3/5
Great

Is this puppy milk replacer right for my pet?

Breed Size

All Breeds

Lifestage

Senior

Top Ingredients

Rice flour, dried skimmed milk, dried meat solubles, animal fat (preserved with BHA and BHT), dried whey protein concentrate

Special Diet

High-Protein
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Frequently Asked Questions about Puppy Milk Replacers

Can newborn puppies eat puppy food?

Newborn puppies cannot usually eat puppy food, as their digestive systems are not fully developed. Newborn puppies should nurse from their mother or be bottle-fed a milk replacer formulated specifically to meet their nutritional needs. See your vet for an exam and detailed instructions on care before attempting to feed very young or orphaned puppies.

How long do puppies need to stay on milk replacer?

Puppies usually need to stay on milk replacer until at least 3 to 4 weeks of age to ensure adequate nutrition and easy digestion, but only if mother's milk is not available. The best food for the youngest puppies is always natural mother's milk, although puppy milk replacer is a nutritious substitute in its absence. After 4 to 6 weeks, you can start introducing them to wet puppy food and decrease the amount of milk replacer you're feeding gradually. Always talk to your vet for the best guidance on feeding and caring for nursing puppies.

What can you substitute for puppy milk?

You can substitute specially formulated puppy milk replacers for puppy milk if the mother is not around or able to feed the puppies. If you are caring for nursing puppies, be sure to seek detailed feeding advice from your vet to ensure you are providing adequate nutrition. You can find a wide variety of puppy milk replacers at Chewy to help your furry friends grow up healthy and thrive!